Journals / Türk Nöroloji Dergisi / 2018 / Cilt: 24 - Sayı: 4

Association Between Mitral Valve Prolapse, Migraine, and White Matter Hyperintensities on Magnetic Resonance Imaging

Mitral Kapak Prolapsusu, Migren ve Manyetik Rezonans Görüntülemede Beyaz Cevher Hiperintensiteleri Arasındaki İlişki

Pages
323–329
Publication Date
2022-11-05
DOI
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⚡ TL;DR(Too Long; Didn't Read)

All patients, both those with migraine and controls were screened with echocardiography to assess for MVP and with brain magnetic resonance imaging to evaluate the presence of any WMHs.Results: The prevalence of MVP was found to be higher in the migraine group (p

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: Migraine is linked with an elevation in vascular risk factors, ischemic stroke, and a variety of constitutional brain lesions.
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Key Findings & Data:In this study, an association between mitral valve prolapse (MVP), migraine, and the presence of brain white matter hyperintensities (WMHs) were evaluated among adult subjects with migraine headache devoid of any traditional vascular risk factors.Materials and Methods: Four hundred subjects (200 subjects with migraine headache, 200 healthy controls; age range 18-50 years) were incorporated in the retrospective study.
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Conclusion & Impact:All patients, both those with migraine and controls were screened with echocardiography to assess for MVP and with brain magnetic resonance imaging to evaluate the presence of any WMHs.Results: The prevalence of MVP was found to be higher in the migraine group (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: Migraine is linked with an elevation in vascular risk factors, ischemic stroke, and a variety of constitutional brain lesions. However, the pathogenesis of this relationship is still inexplicit. The link between cardiac diseases and comorbid migraine-ischemic stroke might be a vascular disease involving both heart and brain. In this study, an association between mitral valve prolapse (MVP), migraine, and the presence of brain white matter hyperintensities (WMHs) were evaluated among adult subjects with migraine headache devoid of any traditional vascular risk factors.Materials and Methods: Four hundred subjects (200 subjects with migraine headache, 200 healthy controls; age range 18-50 years) were incorporated in the retrospective study. Existence of a headache compatible with migraine was diagnosed according to the International Headache Society-2 criteria. The participants were devoid of any known comorbid diseases, vascular risk factors or inflammatory diseases. All patients, both those with migraine and controls were screened with echocardiography to assess for MVP and with brain magnetic resonance imaging to evaluate the presence of any WMHs.Results: The prevalence of MVP was found to be higher in the migraine group (p

Özet

Amaç: Migren, iskemik inme ve bazı yapısal beyin lezyonları gelişimi gibi vasküler risk faktörlerinde artış ile ilişkilendirilmektedir. Bununla birlikte bu ilişkinin patogenezi halen netleşmemiştir. Kardiyak hastalıklar ve iskemik inme ile komorbidite gösterebilen migrenin bunlarla bağlantısı, hem kalp hem de beyni etkileyen vasküler bir hastalık olması şeklinde açıklanabilir. Bu çalışmada, geleneksel vasküler risk faktörleri olmayan genç-erişkin migren hastalarında mitral kapak prolapsusu (MVP) ile migren ve beyaz cevher hiperintensitesi (BCH) arasındaki ilişki incelendi. Gereç ve Yöntem: Bu retrospektif çalışmaya 400 olgu alındı (200 migren ve 200 sağlıklı kontrol; yaş aralığı 18-50 yaş). Migren tanısı Uluslararası Baş Ağrısı Toplumu-2 kriterlerine göre kondu. Katılımcıların bilinen vasküler risk faktörleri, enflamatuvar veya eşlikçi başka hastalıkları yoktu. Migrenli kişiler ve sağlıklı kontrollere transtorasik ekokardiyografi yapılarak MVP varlığı; beyin manyetik rezonans görüntüleme yapılarak BCH olup olmadığı tarandı. Bulgular: Migrenli kişilerde MVP prevelansı, kontrollere göre anlamlı yüksek (p

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Cite This Article

AVCI, A. Y., AKINCI, S., LAKADAMYALI, H., TOPRAK, M. K. (2022). Association Between Mitral Valve Prolapse, Migraine, and White Matter Hyperintensities on Magnetic Resonance Imaging. Türk Nöroloji Dergisi, Cilt: 24 - Sayı: 4, 323–329. https://ajindex.com/articles/636805

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References (10)

  1. Ertas M, Baykan B, Kocasoy OE, et al. One-year prevalence and the impact of migraine and tension-type headache in Turkey: A nationwide home-based study in adults. J Headache Pain 2012;13:147-157.
  2. Lipton RB, Bigal ME, Damond M, Freitag F, Reed ML, Stewart WF; AMPP Advisory Group. Migraine prevalence, disease burden, and the need for preventive therapy. Neurology 2007;68:343-349.
  3. Adelborg K, Szepligeti SK, Holland-Bill L, et al. Migraine and risk of cardiovascular diseases: Danish population based matchedcohort study. BMJ 2018;360:k96. Spector JT, Kahn SR, Jones MR, Jayakumar M, Dalal D, Nazarian S. Migraine headache and ischemic stroke risk: an updated meta-analysis. Am J Med 2010;123:612-624. Tietjen GE. Migraine and ischaemic heart disease and stroke: Potential mechanisms and treatment implications. Cephalalgia 2007;27:981-987.
  4. Kurth T, Ridker PM, Buring JE. Migraine and biomarkers of cardiovascular disease in women. Cephalalgia 2007;28:49-56. Schwedt T. The migraine association with cardiac anomalies, cardiovascular disease and stroke. Neurol Clin 2009;27:513-523.
  5. Delling FN, Vasan RS. Epidemiology and pathophysiology of mitral valve prolapse: New insight into disease progression, genetics, and molecular basis. Circulation 2014:;27:2158-2170.
  6. Zuppiroli A, Rinaldi M, Kramer-Fox R, Favilli S, Roman MJ, Devereux RB. Natural history of mitral valve prolapse. Am J Cardiol 1995;75:1028- 1032. Heck AF. Neurologic aspects of mitral valve prolapse. Angiology 1989;40:743-751.
  7. Freed LA, Levy D, Levine RA, et al. Prevalence and clinical outcome of mitral valve prolapse. New Engl J Med 1999;341:1-7.
  8. Swartz RH, Kern RZ. Migraine is associated with magnetic resonance imaging white matter abnormalities: a meta-analysis. Arch Neurol 2004;61:1366-1368.
  9. Kurth T, Mohammed S, Maillard P, et al. Headache, migraine, and structural brain lesions and function: Population based epidemiology of vascular aging- MRI study. BMJ 2011;342:c7357. Kruit MC, Buchem MA, Launer LJ, Terwindt GM, Ferrari MD. Migraine is associated with an increased risk of deep white matter lesions, subclinical posterior circulation infarcts and brain iron accumulation: The populationbased MRI CAMERA study. Cephalalgia 2010;30:129-136.
  10. Ferrari MD, Klever RR, Terwindt GM, Ayata C, van den Maagdenberg AM. Migraine pathophysiology: lessons from mouse models and human genetics. Lancet Neurol 2015;14:65-80. Edvinsson L. CGRP receptor antagonists and antibodies against CGRP and its receptor inmigraine treatment. Br