Journals / Türk Nöroloji Dergisi / 2019 / Cilt: 25 - Sayı: 2

The Contribution of Neuroimaging to Diagnosis in Idiopathic Intracranial Hypertension

İdiyopatik İntrakraniyal Hipertansiyonda Nöro-Görüntülemenin Tanıya Katkısı

Pages
58–62
Publication Date
2022-11-05
DOI
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When MRI and MRV examinations were evaluated in terms of the presence of additional evidence supporting diagnosis, there was fair agreement for MRI (κ=0.333, p=0.021), and substantial agreement for MRV (κ=0.735, p

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: Due to difficulties in diagnosis, the presence of patients with idiopathic intracranial hypertension (IIH) without papilledema has led to the addition of neuro-radiologic features, which are indicative of increased intracranial pressure, to new diagnostic criteria.
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Key Findings & Data:In this study, it was aimed to investigate the inter-rater agreement regarding the evaluation of neuroimaging findings of patients diagnosed as having definite IIH and to detect their possible contribution to diagnosis.
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Conclusion & Impact:When MRI and MRV examinations were evaluated in terms of the presence of additional evidence supporting diagnosis, there was fair agreement for MRI (κ=0.333, p=0.021), and substantial agreement for MRV (κ=0.735, p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: Due to difficulties in diagnosis, the presence of patients with idiopathic intracranial hypertension (IIH) without papilledema has led to the addition of neuro-radiologic features, which are indicative of increased intracranial pressure, to new diagnostic criteria. In this study, it was aimed to investigate the inter-rater agreement regarding the evaluation of neuroimaging findings of patients diagnosed as having definite IIH and to detect their possible contribution to diagnosis. Materials and Methods: Forty-one consecutive patients with definite IIH who had both brain magnetic resonance imaging (MRI) and MR-venography (MRV) examinations were included in the study. Images were evaluated by two experienced neurologists, who were blinded to the clinical presentation of the cases, in terms of empty sella, flattened posterior globe/sclera, tortuosity of optic nerve, transverse sinus stenosis/hypoplasia, and additionally non-specific white matter lesions using a standardized form. The results were evaluated using kappa (κ) analysis in terms of inter-rater agreement. Results: The mean body mass index and cerebral spinal fluid opening pressure of the patients (38 female, 3 male) were 29.2±5.48 kg and 371±149.4 mmH2O, respectively. Six patients did not have papilledema. When MRI and MRV examinations were evaluated in terms of the presence of additional evidence supporting diagnosis, there was fair agreement for MRI (κ=0.333, p=0.021), and substantial agreement for MRV (κ=0.735, p

Özet

Amaç: Tanısında zorluklar yaşanabilen papilödemsiz idiyopatik intrakraniyal hipertansiyon (İİH) olgularının varlığı, yeni tanı ölçütlerinde kafa içi basınçartışına işaret eden nöro-radyolojik özelliklerin eklenmesine neden olmuştur. Bu çalışmada kesin İİH tanısı konmuş hastaların nöro-görüntüleme bulgularınınaraştırmacılar arasındaki tutarlılığının ve tanıya olan olası katkısının incelenmesi hedeflenmiştir.Gereç ve Yöntem: Kesin İİH tanısıyla takipli, kraniyal manyetik rezonans görüntüleme (MRG) ve MR-venografi (MRV) incelemelerinin her ikisine ulaşılabilenardışık 41 hasta çalışmaya dahil edildi. Görüntülemeler boş sella, glob posteriorunda düzleşme, optik sinir kıvrımlanması, transvers sinüs stenozu/hipoplazisi veek olarak non-spesifik ak madde lezyonları yönünden, olguların klinik verilerine kör, alanında tecrübeli iki ayrı nörolog tarafından standart bir formla incelendi.Sonuçlar araştırmacılar arası uyum bakımından kappa (κ) analizi kullanılarak değerlendirildi.Bulgular: Hastaların (38 kadın, 3 erkek) ortalama vücut kitle indeksi 29,2±5,48; beyin omurilik sıvısı açılış basıncı 371±149,4 mmH2O idi. Altı hastadapapilödem saptanmadı. MRG ve MRV incelemeleri tanıyı destekleyen ek bir bulgu olup olmamasına göre değerlendirildiğinde, araştırmacılar arasında MRGaçısından zayıf (κ=0,333, p=0,021), MRV açısından iyi düzeyde (κ=0,735, p

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Cite This Article

EKİZOĞLU, E., SAMANCI, Y., SAMANCI, B., BAYKAN, B., YEŞİLOT, N., ÇOBAN, O., ŞAHİN, E. (2022). The Contribution of Neuroimaging to Diagnosis in Idiopathic Intracranial Hypertension. Türk Nöroloji Dergisi, Cilt: 25 - Sayı: 2, 58–62. https://ajindex.com/articles/636742

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