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Journals / Epilepsi / 2016 / Cilt: 22 - Sayı: 0

Immunotherapy Responsive Epilepsies: General Clinical Features, Commonly Detected Antibodies and Treatment Studies

İmmünoterapiye Yanıtlı Epilepsiler: Genel Klinik Özellikler, Sık Saptanan Antikorlar ve Tedavi Çalışmaları

ESME EKİZOĞLU TURGUT
Betül BAYKAN
Journal
Epilepsi
Pages
37–45
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In this paper, epileptic pictures with a known autoimmune aspect as well as those pictures with recent increased awareness due to the discovery of neuronal auto-antibodies responding to immunotherapies and their management options are summarized.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:The role of immunity and inflammation in epilepsy has long been considered and in recent years, discovery of some antibodies against to various neuronal antigens especially in cases refractory to conventional anti-epileptic drugs raised the concept of “autoimmune epilepsy”.
📊
Key Findings & Data:Immunotherapy may lead to significant benefits in cases with suspicion of autoimmune etiology.
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Conclusion & Impact:In this paper, epileptic pictures with a known autoimmune aspect as well as those pictures with recent increased awareness due to the discovery of neuronal auto-antibodies responding to immunotherapies and their management options are summarized.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

The role of immunity and inflammation in epilepsy has long been considered and in recent years, discovery of some antibodies against to various neuronal antigens especially in cases refractory to conventional anti-epileptic drugs raised the concept of “autoimmune epilepsy”. Immunotherapy may lead to significant benefits in cases with suspicion of autoimmune etiology. In this paper, epileptic pictures with a known autoimmune aspect as well as those pictures with recent increased awareness due to the discovery of neuronal auto-antibodies responding to immunotherapies and their management options are summarized.

Özet

Epilepside immünite ve enflamasyonun rolü üzerinde uzun zamandır durulmakta olup, son yıllarda özellikle geleneksel antiepileptik ilaçlara dirençli olgularda birtakım nöronal antijenlere karşı gelişen antikorların saptanması ile “otoimmün epilepsi” kavramı doğmuştur. Otoimmün etiyolojiden şüphelenilen olgularda immün tedavinin başarılı olduğu görülmüştür. Bu yazıda otoimmün boyutu bilinen epilepsi tablolarının yanısıra, son yıllarda önemi artan immüntedaviye yanıtlı nöronal otoantikorlarla ilişkili tablolar ve tedavi seçenekleri özetlenmiştir.

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Cite This Article

TURGUT, E. E., BAYKAN, B. (2016). Immunotherapy Responsive Epilepsies: General Clinical Features, Commonly Detected Antibodies and Treatment Studies. Epilepsi, Cilt: 22 - Sayı: 0, 37–45. https://ajindex.com/articles/159954

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