Journals / Türk Nöroloji Dergisi / 2021 / Cilt: 27 - Sayı: 4

Determination of Ketosis with Breath Acetone Measurement Sensor on Ketogenic Diet: A Prospective Controlled Study

Ketojenik Diyette Nefes Aseton Ölçüm Sensörüyle Ketozisin Belirlenmesi: Prospektif Kontrollü Bir Çalışma

Pages
407–412
Publication Date
2022-11-05
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusion: The breath acetone measurement method can be used practically and reliably for ketone monitoring in individuals undergoing ketogenic diet therapy.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: Ketogenic diet may be effective in the treatment of neurological diseases such as epilepsy.
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Key Findings & Data:Materials and Methods: A total of 18 adults, which included 10 adults in the treatment group and 8 adults in the control group, were enrolled in the study.
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Conclusion & Impact:Conclusion: The breath acetone measurement method can be used practically and reliably for ketone monitoring in individuals undergoing ketogenic diet therapy.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: Ketogenic diet may be effective in the treatment of neurological diseases such as epilepsy. Breath acetone measurement can be a practical method in the tracking of ketogenic diet treatment. This study aimed to determine the correlation between breath acetone levels and urinary ketone levels of adult individuals undergoing ketogenic diet therapy. Materials and Methods: A total of 18 adults, which included 10 adults in the treatment group and 8 adults in the control group, were enrolled in the study. Ketogenic diet therapy was applied to the intervention group for 1 week. For 1 week, breath acetone measurements of both the treatment group and control group were taken every day at the same time on fasting. In all participants, urine ketones were measured at the same time every day. Results: Breath acetone and urine ketone values on days 3-5 were significantly higher in the treatment group than that in the control group. Positive correlations were found between breath acetone levels and urine ketone levels in the treatment group in all 7 days. Conclusion: The breath acetone measurement method can be used practically and reliably for ketone monitoring in individuals undergoing ketogenic diet therapy.

Özet

Amaç: Epilepsi gibi nörolojik hastalıkların tedavisinde ketojenik diyetin etkili olabileceği düşünülmektedir. Ketojenik diyet tedavisinin takibinde nefes aseton ölçümü pratik bir yöntem olarak ön plana çıkmaktadır. Bu çalışmada, ketojenik diyet tedavisi alan yetişkin bireylerin nefes aseton düzeyleri ile idrar keton düzeyleri arasındaki ilişkinin belirlenmesi amaçlanmıştır. Gereç ve Yöntem: Çalışmaya tedavi grubunda 10 yetişkin ve kontrol grubunda 8 yetişkin olmak üzere toplam 18 yetişkin dahil edilmiştir. Müdahale grubuna bir hafta süreyle ketojenik diyet tedavisi uygulanmıştır. Bir hafta boyunca, hem müdahale grubu hem de kontrol grubunun nefes aseton ölçümleri her gün aynı saatte aç karnına alınmış ve tüm katılımcıların idrar keton ölçümleri her gün aynı saatte yapılmıştır. Bulgular: Müdahale grubunda 3., 4. ve 5. günlerde nefes aseton ve idrar keton değerleri kontrol grubuna göre anlamlı olarak yüksek bulunmuştur. Müdahale grubundaki nefes aseton seviyeleri ile idrar keton seviyeleri arasındaki ilişki incelendiğinde 7 günün tamamında pozitif korelasyonlar belirlenmiştir. Sonuç: Ketojenik diyet tedavisi gören bireylerin keton takibinde nefes aseton ölçüm yönteminin pratik ve güvenilir olarak kullanılabileceği tespit edilmiştir.

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Cite This Article

GARİPOĞLU, G., KOÇ, B. M., ÖZLÜ, T. (2022). Determination of Ketosis with Breath Acetone Measurement Sensor on Ketogenic Diet: A Prospective Controlled Study. Türk Nöroloji Dergisi, Cilt: 27 - Sayı: 4, 407–412. https://ajindex.com/articles/636543

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