Journals / Türk Nefroloji Diyaliz ve Transplantasyon Dergisi / 2015 / Cilt: 24 - Sayı: 3

Kadaverik Böbrek Transplant Alıcısında Geriye Dönüşümsüz Tek Taraflı Jinekomasti

Irreversible Unilateral Gynecomastia in a Cadaveric Kidney Transplant Recipient Kadaverik Böbrek Transplant Alıcısında Geriye Dönüşümsüz

Pages
332–336
Publication Date
2022-11-05
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

However, GM may persist after the discontinuation of CsA.

📌 3 Key Takeaways

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Objective & Hypothesis:Gynecomastia (GM) is a benign condition characterized by enlargement of the male breast, which is attributed to proliferation of the glandular tissue and local fat deposition.
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Key Findings & Data:We present here a case with unilateral GM that gradually developed after cadaveric renal transplantation A 37-year-old man who underwent renal transplantation in 2010 was admitted to our center with complaints of unilateral right-sided GM.
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Conclusion & Impact:However, GM may persist after the discontinuation of CsA.
🔬Design:Research Article
📍Scope:2010 Verileri
⚙️Variables:Domain Parameters

Abstract

Gynecomastia (GM) is a benign condition characterized by enlargement of the male breast, which is attributed to proliferation of the glandular tissue and local fat deposition. We present here a case with unilateral GM that gradually developed after cadaveric renal transplantation A 37-year-old man who underwent renal transplantation in 2010 was admitted to our center with complaints of unilateral right-sided GM. There was no nipple discharge, pain or redness in the affected breast. His graft was functioning well. His medications consisted of Cyclosporine (CsA) at a dose of 200 mg/d, mycophenolic acid at a dose of 2000 mg/d, prednisolone at a dose of 5 mg/d, doxazosin 8 mg/d, and metoprolol 50 mg/d. CsA-induced GM was considered, and CsA was switched to sirolimus. After two months, GM regression was not observed. Fine needle aspiration of a right breast mass revealed a benign condition. Estrogen and progesterone receptor was strongly positive on microscopic examination of the tissue.GM is a rare condition that is generally caused by CsA treatment. However, GM may persist after the discontinuation of CsA.

Özet

Jinekomasti, bölgesel yağ birikimi ve glanduler dokunun proliferasyonunu ile olan, erkek memesinin büyümesi ile karakterize benign bir durumdur. Biz burada, kadaverik böbrek transplantasyonu sonrası gelişen tek taraflı jinekomasti olgusunu sunduk 2010 yılında böbrek transplantasyonu olan 37 yaşında bir erkek hasta, merkezimize tek-sağ taraflı jinekomasti bulgusu ile kabul edildi. Etkilenen memede ağrı, kızarıklık, akıntı yoktu. Greft fonksiyonu iyiydi. İlaçları siklosporin 200 mg/gün, mikofenolik asit 2000 mg/gün, prednizolon 5 mg/gün, doksazosin 8 mg/gün, metoprolol 50 mg/gün idi. Siklosporine bağlı jinekomasti düşünüldü ve siklosporin sirolimus ile değiştirildi. 2 ay sonra jinekomastide gerileme gözlenmedi. Sağ memeden yapılan ince iğne aspirasyon biopsisi benign sonuç geldi. Dokuların mikroskobik tetkikinde; östrojen ve progesteron reseptörleri güçlü pozitif geldi Kalsinörin tedavisi ile meydana gelen jinekomasti nadir bir durumdur. Fakat jinekomasti kalsinörin kesildikten sonra kalıcı olabilir

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Cite This Article

TURGUTALP, K., KIYKIM, A., KARA, T., DEMİR, S., KÖŞECİ, T., BARDAK, S., POLAT, A., ÇİÇEK, N., ÇINAR, Ü. (2022). Kadaverik Böbrek Transplant Alıcısında Geriye Dönüşümsüz Tek Taraflı Jinekomasti. Türk Nefroloji Diyaliz ve Transplantasyon Dergisi, Cilt: 24 - Sayı: 3, 332–336. https://ajindex.com/articles/636248

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