Journals / Türk Nefroloji Diyaliz ve Transplantasyon Dergisi / 2017 / Cilt: 26 - Sayı: 3

Association Between Vascular Access Type and Visceral and Peripheral Body Fat, Nutritional and Inflammatory Parameters in Incident Hemodialysis Patients

Hemodiyaliz Hastalarında Damar Ulaşım Yolu Tipi ile Visseral ve Periferal Yağ Dokusu, Nütrisyonel ve İnflamatuvar Parametrelerin İlişkisi

Pages
261–270
Publication Date
2022-11-05
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Further prospective studies are needed to illuminate therelationship between vascular access type, nutritional parameters and body composition in HD patients.

📌 3 Key Takeaways

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Objective & Hypothesis:OBJECTIVE: Central venous catheters (CVCs) are preferred when a patent arteriovenous fistula(AVF) cannot be created.
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Key Findings & Data:CVCs have been shown to be associated with increased inflammation andmortality.
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Conclusion & Impact:Further prospective studies are needed to illuminate therelationship between vascular access type, nutritional parameters and body composition in HD patients.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

OBJECTIVE: Central venous catheters (CVCs) are preferred when a patent arteriovenous fistula(AVF) cannot be created. CVCs have been shown to be associated with increased inflammation andmortality. In the present study, we aimed to investigate a probable association between the vascularaccess type and BMI, total body fat, truncal fat, muscle mass, visceral (periaortic) fat, and themalnutrition inflammation atherosclerosis and calcification score (MIAC) in hemodialysis patients.MATERIAL and METHODS: A total of 119 patients were involved. Ninety patients had patentAVF and 29 patients were undergoing hemodialysis via permanent jugular catheter. Two-dimensionalechocardiography was performed to detect valvular calcification. Computed tomography was performedin all patients to detect the amount of thoracic periaortic fat tissue (T-PAFT). Biochemical analyses wereperformed using c8000 Architect. MIAC scores were calculated using valvular calcification, albumin,and CRP. Total body fat and truncal fat were detected using the bio impedance analysis method. Aorticcalcification score (AoCS) was calculated using routine chest x-rays.RESULTS: MIAC and AoCS was higher in patients with CVC (p=0.02 and 0.032). T-PAFT was higherin patients with AVF (1631.5±645 vs 1112.2±606.8; p=0.035). CRP was higher in patients with CVC(p=0.04). Hemodialysis vintage, calcium and albumin were lower in patients with CVC (p=0.01).Truncal fat (%), cholesterol and 25-OH vitamin D levels were lower in patients with CVC (p=0.04,p=0.02, p=0.03). T-PAFT was a significant predictor of vascular access type in favour of AVF (t=-2.17;p=0.04).CONCLUSION: The present study revealed that HD patients with CVC had increased inflammationand decreased nutrition, visceral and truncal fat. Further prospective studies are needed to illuminate therelationship between vascular access type, nutritional parameters and body composition in HD patients.

Özet

AMAÇ: Santral venöz kateterler (SVK) başarılı bir arteriovenöz fistül (AVF) oluşturulamadığıdurumlarda tercih edilirler. SVK'ler artmış inflamasyon ve mortaliteyle birliktedir. Bu çalışmada,hemodiyaliz hastalarında damar ulaşım yolu tipi ile vücut kitle indeksi (VKİ), toplam vücut yağı,gövdesel yağ, kas kitlesi, visseral (periaortik) yağ, malnutrisyon, inflamasyon ateroskleroz, kalsifikasyonskoru (MIAC) arasındaki muhtemel ilişki araştırılmıştır.GEREÇ ve YÖNTEMLER: 119 hasta çalışmaya alındı. 90 hastada AVF, 29 hasta kalıcı jugulerkateter mevcuttu. Valvüler kalsifikasyon iki boyutlu ekokardiyografi ile torasik periaortik yağ dokusu(T-PAFT) bilgisayarlı tomografi ile saptandı. Biyokimyasal analizler c8000 Architect cihazıyla çalışıldı.MIAC skoru, valvüler kalsifikasyon skoru, albumin ve CRP değerleri ile hesaplandı. Toplam vücutyağı ve trunkal yağ biyoimpedans analiz yöntemi ile çalışıldı. Aortik kalsifikasyon skoru (AoCS) rutinakciğer grafisinden hesaplandı. BULGULAR: MIAC ve AoCS, SVK olan hastalarda daha yüksekti (p=0,02 ve 0,032). T-PAFT, AVF grubunda daha yüksekti (1631,5±645'ekarşı 1112,2±606,8; p=0,035). CRP, SVK olan hastalarda daha yüksekti (p=0,04). Hemodiyaliz süresi, kalsiyum ve albumin SVK olan grupta dahadüşüktü (p=0,01). Gövde yağ oranı (%), kolesterol ve 25-OH vitamin D düzeyi SVK olan grupta daha düşüktü (p=0.04, p=0.02, p=0.03). T-PAFTmiktarı AVF lehine damar ulaşım yolunun anlamlı bir belirleyicisi idi (t=-2,17; p=0,04).SONUÇ: Çalışmada SVK'i olan hemodiyaliz hastalarının artmış inflamasyon, azalmış nütrisyon, visseral ve gövdesel yağ oranına sahip olduğugözlenmiştir.

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Cite This Article

GENÇTOY, G., HABERAL, C., SABA, T., BİRTAY, T. (2022). Association Between Vascular Access Type and Visceral and Peripheral Body Fat, Nutritional and Inflammatory Parameters in Incident Hemodialysis Patients. Türk Nefroloji Diyaliz ve Transplantasyon Dergisi, Cilt: 26 - Sayı: 3, 261–270. https://ajindex.com/articles/636103

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