Journals / Türk Mikrobiyoloji Cemiyeti Dergisi / 2007 / Cilt: 37 - Sayı: 1

The role of some lactic acid bacteria used as probiotic on cholesterol assimilation and bile salt deconjugation

Probiyotik olarak kullanılan bazı laktik asit bakterilerinin kolesterol asimilasyonu ve safra tuzları dekonjugasyonundaki rolleri

Pages
62–68
Publication Date
2022-11-05
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The first one is the reduction of absorption of cholesterol from the intestinal tract and the other one is bile salt deconjugation by the bacteria.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Cardiovascular disease is the most important cause of death in the western countries and it is strongly associated with hypercholesterolemia.
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Key Findings & Data:Decreasing serum cholesterol is, therefore, very important to prevent cardiovascular disease.
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Conclusion & Impact:The first one is the reduction of absorption of cholesterol from the intestinal tract and the other one is bile salt deconjugation by the bacteria.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Cardiovascular disease is the most important cause of death in the western countries and it is strongly associated with hypercholesterolemia. Decreasing serum cholesterol is, therefore, very important to prevent cardiovascular disease. One of the beneficial health effects related to probiotics is their ability to reduce serum cholesterol. The mechanism of action of probiotics on cholesterol reduction is unclear, although a number of possible mechanisms have been proposed. Two main mechanisms have been proposed. The first one is the reduction of absorption of cholesterol from the intestinal tract and the other one is bile salt deconjugation by the bacteria.

Özet

Yüksek kolesterol ile bağlantılı olan kalp-damar hastalıkları, batılı ülkelerdeki en önemli ölüm nedenlerinden biridir. Bu sebeple, serum kolesterol seviyelerinin düşürülmesi, özellikle kalp-damar hastalıklarının önlenmesi bakımından büyük önem taşımaktadır. Probiyotiklerin sağlığa faydalı etkilerinden biri de serum kolesterolünü azaltma kabiliyetleridir. Probiyotiklerin kolesterol konsantrasyonunu azaltabilmelerini sağlayan mekanizma tam olarak belirlenememekle birlikte, bu konuda çeşitli mekanizmalar öne sürülmüştür. Öne sürülen iki temel mekanizma, bakteriler tarafından, diyetle alınan kolesterolün bağırsaklardan emiliminin azaltılması ve safra tuzlarının dekonjugasyonudur.

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Cite This Article

ASLIM, B., TOK, E. (2022). The role of some lactic acid bacteria used as probiotic on cholesterol assimilation and bile salt deconjugation. Türk Mikrobiyoloji Cemiyeti Dergisi, Cilt: 37 - Sayı: 1, 62–68. https://ajindex.com/articles/636022

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