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Journals / Türk Klinik Biyokimya Dergisi / 2013 / Cilt: 11 - Sayı: 1

NGAL As a Potential Diagnostic Biomarker

Potansiyel Tanısal Bir Biyobelirteç Olarak Nötrofil Jelatinaz İlişkili Lipokalin

Emel ALTEKİN
Yasin KENESARI
Pages
37–41
Publication Date
2022-11-05
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The current status of one of the most promising novel biomarkers, namely neutrophil gelatinase-associated lipocalin (NGAL), is presented in this review.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Neutrophil gelatinase-associated lipocalin (NGAL), is a small, robust protein expressed by neutrophils and various epithelia, including the renal proximal tubules.
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Key Findings & Data:While initially proposed as a marker for infections and certain adenocarcinomas, it is now apparent that its early and dramatic rise in urine after renal injury may make it a useful marker of such injury.
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Conclusion & Impact:The current status of one of the most promising novel biomarkers, namely neutrophil gelatinase-associated lipocalin (NGAL), is presented in this review.
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Neutrophil gelatinase-associated lipocalin (NGAL), is a small, robust protein expressed by neutrophils and various epithelia, including the renal proximal tubules. While initially proposed as a marker for infections and certain adenocarcinomas, it is now apparent that its early and dramatic rise in urine after renal injury may make it a useful marker of such injury. The current status of one of the most promising novel biomarkers, namely neutrophil gelatinase-associated lipocalin (NGAL), is presented in this review.

Özet

Nötrofil jelatinaz ilişkili lipokalin (NGAL), nötrofiller ve böbrek proksimal tübüllerini de içeren çeşitli epitellerden sentez edilen küçük, stabil bir proteindir. Başlangıçta enfeksiyon ve bazı adenokanser türleri için tanısal amaçlı kullanımı ileri sürülürken, böbrek hasarı sonrası idrarda dramatik yükselişi NGALi günümüzde böbrek hasarı için kullanışlı bir biyobelirteç yapmıştır. Bu derlemede yeni bir biyobelirteç olarak NGAL ele alınacaktır.

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Cite This Article

ALTEKİN, E., KENESARI, Y. (2022). NGAL As a Potential Diagnostic Biomarker. Türk Klinik Biyokimya Dergisi, Cilt: 11 - Sayı: 1, 37–41. https://ajindex.com/articles/634468

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References (14)

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