Journals / Türk Klinik Biyokimya Dergisi / 2013 / Cilt: 11 - Sayı: 3

Inflammation Biomarkers in Patients with Acute Myocardial Infarction

Akut Miyokard İnfarktüslü Hastalarda İnşamasyon Belirteçleri

Pages
93–97
Publication Date
2022-11-05
DOI
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⚡ TL;DR(Too Long; Didn't Read)

Cardiac tests were performed immediately at admission. hsCRP and procalcitonin concentrations of AMI patients were measured at the time of admission and at 48 hours after the admission with chemiluminescence immunassay.Results: HsCRP concentrations of 34 male patients aged 58.6±11.3 (mean±SD) were 4.1±3.8 and 43.5±34.5 mg/dl respectively at admission and 48th hour, procalcitonin concentrations were 0.29±1.4 ve 0.93±3.2 ng/mL respectively at admission and 48 hours after admission. 0 and 48th hour concentrations of both hsCRP and procalcitonin were significantly different (p

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: In recent years hsCRP and procalcitonin has started to be used in diagnosis and assessment of the prognosis of cardiovascular diseases.
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Key Findings & Data:Materials and Methods: 34 male patients admitted to emergency department for angina pectoris and diagnosed with AMI were included in the study.
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Conclusion & Impact:Cardiac tests were performed immediately at admission. hsCRP and procalcitonin concentrations of AMI patients were measured at the time of admission and at 48 hours after the admission with chemiluminescence immunassay.Results: HsCRP concentrations of 34 male patients aged 58.6±11.3 (mean±SD) were 4.1±3.8 and 43.5±34.5 mg/dl respectively at admission and 48th hour, procalcitonin concentrations were 0.29±1.4 ve 0.93±3.2 ng/mL respectively at admission and 48 hours after admission. 0 and 48th hour concentrations of both hsCRP and procalcitonin were significantly different (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: In recent years hsCRP and procalcitonin has started to be used in diagnosis and assessment of the prognosis of cardiovascular diseases. In this study we aimed to evaluate the prognostic significance of alterations in C-reactive protein (CRP) and procalcitonin levels, in male patients with acute myocardial infarction (AMI). Materials and Methods: 34 male patients admitted to emergency department for angina pectoris and diagnosed with AMI were included in the study. Patients with obesity smoking and chronic diseases were excluded. Cardiac tests were performed immediately at admission. hsCRP and procalcitonin concentrations of AMI patients were measured at the time of admission and at 48 hours after the admission with chemiluminescence immunassay.Results: HsCRP concentrations of 34 male patients aged 58.6±11.3 (mean±SD) were 4.1±3.8 and 43.5±34.5 mg/dl respectively at admission and 48th hour, procalcitonin concentrations were 0.29±1.4 ve 0.93±3.2 ng/mL respectively at admission and 48 hours after admission. 0 and 48th hour concentrations of both hsCRP and procalcitonin were significantly different (p

Özet

Amaç: Son yıllarda kardiyovasküler hastalıkların teşhisinde ve prognoz izleminde prokalsitonin ve yüksek duyarlılıklı C Reaktif Protein (hsCRP) kullanılmaya başlanmıştır. Çalışmadaki amacımız akut miyokard infarktüs (AMI) tanısı alan erkek hastaların prognozunda hsCRP ve prokalsitonin düzeylerindeki değişimin önemini araştırmaktır. Gereç ve Yöntem: Hastanemiz acil servisine göğüs ağrısıyla başvuran, AMI tanısı alan 34 erkek hasta çalışmaya dahil edildi. Sigara içen, obez ve kronik hastalığı olanlar çalışma dışı bırakıldı. Hastaların başvuru anında kardiyak, biyokimyasal testleri çalışıldı. AMI tanısı alan hastalarda hsCRP ve prokalsitonin düzeyleri gelişlerinde ve yatışlarının 48. saatinde kemiluminesans immunometrik yöntemle ölçüldü. Bulgular: 58.6+11.3 olan 34 erkek hastaların 0. ve 48.saat hsCRP düzeyleri 4.1±3.8 ve 43.5±34.5 mg/dL, 0. ve 48.saat prokalsitonin düzeyleri 0.29±1.4 ve 0.93±3.2 ng/ml bulundu. Her iki parametrenin 0. saat ve 48. saat düzeyleri arasında anlamlı farklılık saptandı (p

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Cite This Article

ÜSTÜNER, F., KARADEMİRCİ, İ., DOĞAN, N., AYDOĞDU, A. Ç., HANCI, T., MALTAŞ, Ş. (2022). Inflammation Biomarkers in Patients with Acute Myocardial Infarction. Türk Klinik Biyokimya Dergisi, Cilt: 11 - Sayı: 3, 93–97. https://ajindex.com/articles/634462

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