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Journals / Türk Klinik Biyokimya Dergisi / 2019 / Cilt: 17 - Sayı: 2

The Current Median Values of First Trimester Screening Test Parameters for Kayseri Region

İlk Trimester Tarama Testi Parametrelerinin Kayseri Bölgesi İçin Güncel Medyan Değerleri

Nahide Ekici GÜNAY
Pages
70–78
Publication Date
2022-11-05
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Results: Median values for ß-hCG on week 12 and for PAPP-A on week 11 or 12 in the screening tests were significantly lower than current median values (p

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Objective & Hypothesis:Aim: To determine the current median values for hormone parameters used in first trimester screening test for Kayseri province and to compare the median values with those in the software used for reporting of screening test and those detected for other regions found with similar studies.
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Key Findings & Data:Material and Methods: The data from first trimester screening tests of 1108 pregnant women admitted in 2018 were used in the study.
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Conclusion & Impact:Results: Median values for ß-hCG on week 12 and for PAPP-A on week 11 or 12 in the screening tests were significantly lower than current median values (p
🔬Design:Research Article
📍Scope:2018 Verileri
⚙️Variables:Domain Parameters

Abstract

Aim: To determine the current median values for hormone parameters used in first trimester screening test for Kayseri province and to compare the median values with those in the software used for reporting of screening test and those detected for other regions found with similar studies. Material and Methods: The data from first trimester screening tests of 1108 pregnant women admitted in 2018 were used in the study. Free β-hCG (free, beta human chorionic gonadotropin) and PAPP-A (Pregnancy-associated plasma protein A) levels were recorded together with demographic characteristics for pregnant women. We compared MoM values calculated based on weekly median values in the software and newly calculated MoM values. Results: Median values for ß-hCG on week 12 and for PAPP-A on week 11 or 12 in the screening tests were significantly lower than current median values (p

Özet

Amaç: Kayseri bölgesi için, ilk trimester tarama testinde kullanılan hormon parametrelerinin güncel medyan değerlerini hesaplamak, bu medyanları tarama testi raporlarında kullanılan yazılım programında kullanılan medyanlar ve benzer çalışmalarla bulunan diğer bölgelerin medyanları ile karşılaştırmak amaçlanmıştır. Gereç ve Yöntem: 2018 yılında başvuran 1108 gebenin prenatal ikili tarama testi ölçümleri kullanıldı. Gebelerin demografik verileri ile birlikte sβ-hCG (serbest beta-human koryonik gonadotropin) ve PAPP-A (gebelikle ilişkili plazma protein A) düzeyleri kaydedildi. Rapor vermede kullanılan programa girilmiş olan haftalık medyan değerlerine göre hesaplanan medyanların katları (MoM) ile yeni hesaplanan medyanlara göre bulunan MoM değerleri karşılaştırıldı. Bulgular: Tarama testlerinde kullanılan free β-HCG’nin 12. gebelik haftası ile PAPP-A’nın 11 ve 12.hafta medyan değerleri, güncel medyanlardan anlamlı olarak farklı ve düşük olarak bulundu (sırasıyla p

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Cite This Article

GÜNAY, N. E. (2022). The Current Median Values of First Trimester Screening Test Parameters for Kayseri Region. Türk Klinik Biyokimya Dergisi, Cilt: 17 - Sayı: 2, 70–78. https://ajindex.com/articles/634359

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References (13)

  1. de Graaf G, Vis JC, Haveman M, van Hove G, de Graaf EAB, Tijssen JGP, et al. Assessment of prevalence of persons with Down syndrome: a theory based demographic model. J Appl Res Intellect Disabil. 2011; 24:247–62
  2. Parker SE, Mai CT, Canfield MA, Rickard R, Wang Y, Meyer RE,et al. Updated National Birth Prevalence estimates for selected birth defects in the United States, 2004-2006. Birth Defects Res A Clin Mol Teratol. 2010;88(12):1008-16
  3. Acikbas I, Tomatir AG, Akdag B, Koksal A. Retrospective analysis of live birth prevalence of children with Down syndrome in Denizli, Turkey. Genet Mol Res. 2012 Dec 19;11(4):4640-5
  4. Cuckle H. Prenatal Screening Using Maternal Markers. J Clin Med. 2014;3(2):504-20
  5. Akolekar, R, Beta, J, Piccirelli, G, Ogilvie C, and D’Antonio F. Procedure-Related Risk of Miscarriage Following Amniocentesis and Chorionic Villus Sampling: A Systematic Review and MetaAnalysis. Ultrasound in Obstetrics and Gynecology. 2015. 45(1):16-26
  6. Yaron Y, Heifetz S, Ochshorn Y, Lehavi O, Orrurtreger A. Decreased first trimester PAPP-A is a predictor of adverse pregnancy outcome. Prenat Diagn 2002;22: 778-782 7. James DK, Steer PJ, Weiner CP, Gonik B. High risk pregnancy. Saunders, Philadelphia, 1995. p. 614-5
  7. XC Goetzinger KR, Singla A, Gerkowicz S, Dicke JM, Gray DL, Odibo AO. Predicting the risk of preeclampsia between 11 and 13 weeks' gestation by combining maternal characteristics and serum analytes, PAPP-A and free β-hCG. Prenat Diagn 2010;30: 1138-42
  8. Kirkegaard I, Uldbjerg N, Petersen OB, Tørring N, Henriksen TB. PAPP-A, free β-hCG, and early fetal growth identify two pathways leading to preterm delivery. Prenat Diagn 2010;30: 956-63
  9. Fetal Medicine -Basic Science and Clinical Practice 2nd Edition. Charles Rodeck, Martin Whittle. London: Churchill Livingstone, 2008
  10. Noreen, AN, Bin Sharif, Akhtar H, Quratulain AI. Determination of Medians of Biochemical Maternal Serum Markers. Pak Armed Forces Med J 2018; 68 (2): 185-90
  11. Şanlı DB, Kartkaya K. Determination of the median levels of first trimester screening test parameters in our region. Perinatal Journal 2012;20(1):6-11
  12. Polat N, Yazıcı G Polat Y, Ünlü A. The Median Free - hCG and PAPP-A Levels in Mersin Area and Their Association with Pregnancy Complications. Turk Klinik Biyokimya Derg 2005; 3(3): 117-23
  13. Ayyıldız H, Kalaycı M, Yılmaz M, Bozkurt M, Kaya M. İkili tarama testi parametrelerinin bölgesel medyan değerlerinin belirlenmesi. Nobel Med 2018; 1