Journals / Türk Kardiyoloji Derneği Arşivi / 2003 / Cilt: 31 - Sayı: 5

Yavaş koroner akım diffüz aterosklerozun bir bulgusu olabilir: FFR ve IVUS çalışması

Slow coronary flow may be a sign of diffuse atherosclerosis: Contribution of FFR and IVUS

Pages
270–278
Publication Date
2022-11-05
DOI
—
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

In patients with SCF, a strong negative correlation was seen between TIMI frame count and FFR (r=0.551, p

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Objective & Hypothesis:Slow coronary flow (SCF) is a phenomenon characterized by delayed opacification of coronary arteries in the absence of epicardial occlusive disease, in which many etiological factors such as microvascular and endothelial dysfunction, and small vessel disease have been implicated.
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Key Findings & Data:The study population consisted of 19 [8 (42.1%) male, 11 (57.9%) female; age=55.9±9.4 years] patients with SCF.
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Conclusion & Impact:In patients with SCF, a strong negative correlation was seen between TIMI frame count and FFR (r=0.551, p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Slow coronary flow (SCF) is a phenomenon characterized by delayed opacification of coronary arteries in the absence of epicardial occlusive disease, in which many etiological factors such as microvascular and endothelial dysfunction, and small vessel disease have been implicated. We aimed to investigate the epicardial resistance in relation to SCF by using fractional flow reserve (FFR) and intravascular ultrasound (IVUS). Both have been combined to disclose the related epicardial flow resistance and the arterial anatomy. The study population consisted of 19 [8 (42.1%) male, 11 (57.9%) female; age=55.9±9.4 years] patients with SCF. As compared to expected normal values (1.0), FFR values (0.83±0.13) were significantly lower (p=0.0001). In patients with SCF, a strong negative correlation was seen between TIMI frame count and FFR (r=0.551, p

Özet

Yavaş koroner akım, epikardiyal koroner arterlerin tıkayıcı hastalığının yokluğunda koroner arterlerin opak madde ile geç dolması ile karakterize bir fenomendir. Bu fenomen etiyolojikli küçük damar hastalığı ve endotelyal disfonksiyon gibi bir çok etiyolojik faktörler suçlanmıştır. Bizim çalışmamızın amacı, fraksiyonel akım rezervi (FFR) ve intravasküler ultrason (IVUS) kullanarak, yavaş koroner akım ile epikardiyal rezistans arasındaki ilişkiyi araştırmaktı. Çalışmaya toplam 19 yavaş koroner akım saptanan hasta alındı (8 erkek %42.1 ve 11 kadın %57.9). Yaş ortalamaları 55.9±9.4 yıl idi. Bu hastaların FFR değerleri (0.83±0.13) beklenen normal değerlerle (1.0) karşılaştırıldığı zaman oldukça düşük olduğu tespit edildi (p= 0,0001) Yavaş koroner akımlı hastalarda TIMI frame count ve FFR arasında güçlü negatif korelasyon bulundu. (r=-0.551. p

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Cite This Article

DÖVEN, O., ÇAMSARI, A., ÇİÇEK, D., AKKUŞ, N., CİN, V. G., PAKDEMİR, H., PARMAKSIZ, H. T., KATIRCIBAŞI, M. T., ÖZCAN, İ. T. (2022). Yavaş koroner akım diffüz aterosklerozun bir bulgusu olabilir: FFR ve IVUS çalışması. Türk Kardiyoloji Derneği Arşivi, Cilt: 31 - Sayı: 5, 270–278. https://ajindex.com/articles/633871

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References (14)

  1. Tambe AA, Dermany MA, Zimmerman HA, Mascarenhas E. Angina pectoris and slow flow velocity of dye in coronary arteries. A new angiographic finding. Am Heart J 1972
  2. 71 2. Wilson RF, White CW. Intracoronary papaverine: An ideal vasodilator for studies of the coronary circulation in conscious humans. Circulation 1986
  3. 51 3. Vrints C, Herman AG. Role of the endothelium in the regulation of coronary artery tone. Acta Cardioi 1991
  4. 418 4. Mossed M, Yaram R, Gotsman MS, Hasın Y. Hİstologic evidence for small vessel coronary artery disease in patients with angina pectoris and patent large coronary arteries. Circulation 1986
  5. 72 5. Mangieri E, Macchiarelli G, Ciavolella M, et al. Slow coronary flow: clinical and histopathological features in patients with otherwise normal epicardial coronary arteries. Cathel Cardiovasc Diagn 1996
  6. 81 6. Kemp HG Jr, Vokonas PS, Colin PF, Gorlin R. The anginal syndrome associated with normal coronary artcriograms. Report of a six year experience. Am J Med 1973
  7. 42 7. James TN. Small arteries of the heart. Circulation 1977
  8. 14 8. Ralclİffe HL, Redfıeld E. Atherosclerotic stenosis of the extramural and intramural coronary arteries of man. Related lesions. Virchows Arch A Patho Anat 1972
  9. l-10 9. McPherson DD, Hiratzka LF, Lamberth WC, et al. Delineation of the extent of coronary atherosclerosis by high-frequency epicardial echocardiography. N Engl J Med l9875
  10. 9 10. Glagov S, Weisenberg E, Zarins CK, Stankunavicius R, Kol etti s GJ. Compensatory enlargement of human atherosclerotic coronary arteries. N Engl J Med 1987
  11. 5 11. Nissen SE, Gurley JC, Grines CL, et al. Intravascular ultrasound assessment of lumen size-and wall morphology in normal subjects and patients with coronary artery disease. Circulation 1991:84:1087-99 12. Mintz GS, Painter JA, Pichard AD, et al. Atherosclerosis in angiographically "normal" coronary artery reference segments: an intravascular ultrasound study with clinical correlations. J Am Coll Cardioi 1995
  12. 85 13. Tuzcu EM, Kapadia SR, Tutar E, et al. High prevalence of coronary atherosclerosis in asymptomatic teenagers and young adults: evidence from intravascular ultrasound. Circulation 2001
  13. 10 14. Shaw JA, Kingwell BA, Walton AS, et al. Determinants of coronary artery compliance İn subjects with and without angiographic coronary artery disease. J Am Coll Cardioi 2002
  14. 43 15. De flruyne B, Hersbach F, Pijls NHJ, et al. Abnormal