Journals / Türk Kardiyoloji Derneği Arşivi / 2004 / Cilt: 32 - Sayı: 4

Correlation between heart rate variability indices and QT durations in heart failure

Kalp yetersizliğinde kalp hızı değişkenliği parametreleri ile QT sürelerinin eşitliği

Pages
232–238
Publication Date
2022-11-05
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

In the reduced SDNN group (SDNN

📌 3 Key Takeaways

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Objective & Hypothesis:Reduced heart rate variability (HRV) is consistently observed and is acceptedto be due to autonomic dysfunction in patients with heart failure.
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Key Findings & Data:Thirty-nine patients with heartfailure were enrolled in the study in order to monitor 24-hour Holterrecordings.
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Conclusion & Impact:In the reduced SDNN group (SDNN
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Reduced heart rate variability (HRV) is consistently observed and is acceptedto be due to autonomic dysfunction in patients with heart failure. The durationof QT interval and QT dispersion (QTd) is also known to be influenced byautonomic nervous system. The aim of this study is to evaluate the correlationbetween QT interval and QTd with HRV indices. Thirty-nine patients with heartfailure were enrolled in the study in order to monitor 24-hour Holterrecordings. The HRV indices and QT interval dynamicity were analyzed in the samerecordings. QTd measurements were evaluated manually in the 12-leadelectrocardiograms. The low-frequency (LF) and high frequency (HF) power wereexpressed in normalized units(nu). Corrected QT (QTc) intervals were found tobe correlated with HF(nu) (r=0.36, p=0.02), however was negatively correlatedwith LF/HF ratio (r =-0.43, p=0.005) and SDNN (r=-0.37, p=0.01). There was nocorrelation between LF(nu) and QTc intervals. In patients with prolonged QTcinterval (QTc ?440 msn); HF(nu) was significantly higher (16±10 to 9±5, p=0.01) and LF/HF ratio was significantly lower (1.7±0.6 to 3.1±1.6, p= 0.008) compared with patients without prolonged QTc interval. There was no significantdifference in the LF(nu) values between patients with prolonged and normal QTcinterval. In the reduced SDNN group (SDNN

Özet

Kalp yetersizliği olan hastalarda kalp hızı değişkenliğinin (KHD) genellikleazaldığı saptanır ve otonomik disfonksiyonun göstergesi olarak yorumlanır. QTinterval süresi ve QT dispersiyonunun (QTd) otonom sinir sisteminden etkilendiğibilinmektedir. Bu çalışmada, kalp yetersizliği olan olguların, KHD değerleriile QT intervali ve QTd karşılaştırarak aralarındaki ilişki değerlendirildi.Kalp yetersizliği olan 39 olgu çalışmaya alınarak 24-saatlik Holtermonitorizasyonu yapıldı. Hastaların KHD parametreleri ve QT dinamisitesi aynı Holter kayıtlarında değerlendirildi.QT dispersiyonu ise 12-derivasyonluelektrokardiyogramlarda manuel olarak hesaplandı. Çalışmada, düşük frekansın(LF) ve yüksek frekansın (HF) normalize edilmiş (nu) değerleri kullanıldı.Düzeltilmiş QT (QTc); KHD’nin HF(nu) komponenti ile pozitif korelasyongösterirken (r=0.36, p=0.02), LF/HF oranı ve SDNN ile negatif korelasyongösterdi (r=-0.43, p=0.005, r=-0.33, p=0.03). LF(nu) komponenti ile QTcarasında anlamlı korelasyon saptanmadı (r=0.10, p=0.51). Uzamış QTc intervaliolan hastaların (QTc ?440 msn); HF(nu) değerlerinde anlamlı artma (16±10’a 9±5, p=0.01), LF/HF oranlarında anlamlı azalma saptandı (1.7±0.6’ya 3.1±1.6, p=0.008).Uzamış veya normal QTc intervali olan hastaların LF(nu) değerlerinde anlamlıfark görülmedi. Azalmış SDNN grubunda (SDNN

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Cite This Article

TEKİNER, F., EKİCİBAŞI, E., FAZLIOĞLU, M., GEMİCİ, K., CORDAN, J., ÇİÇEK, D. (2022). Correlation between heart rate variability indices and QT durations in heart failure. Türk Kardiyoloji Derneği Arşivi, Cilt: 32 - Sayı: 4, 232–238. https://ajindex.com/articles/633804

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