Journals / Türk Kardiyoloji Derneği Arşivi / 2006 / Cilt: 34 - Sayı: 1

Evaluation of collateral circulation with clinical, electrocardiographic, and angiographic parameters in patients with acute myocardial infarction

Akut miyokard infarktüslü hastalarda kollateral dolaşımın klinik, elektrokardiyografik ve anjiyografik parametrelerle değerlendirilmesi

Pages
22–28
Publication Date
2022-11-05
DOI
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In multiple regression analysis, only RCA occlusion was found to be an independent predictor for CC (r=0.377, p

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Objective & Hypothesis:Objectives: We investigated the presence of collateral circulation (CC) during early period of acute myocardial infarction (AMI) and evaluated its relationship with clinical, electrocardiographic, and angiographic parameters.Study design: In 79 patients (63 men, 16 women; mean age 57 years) who presented within the first six hours of AMI, coronary angiography was performed before primary angioplasty to determine the infarct-related artery (IRA), the number of arteries with significant stenosis (≥50%), localization of stenosis (proximal, middle, or distal), and the presence of CC.
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Key Findings & Data:Collateral circulation to the IRA was graded according to the Rentrop scoring system.Results: Collateral circulation to the IRA was detected in 31 patients (39.2%).
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Conclusion & Impact:In multiple regression analysis, only RCA occlusion was found to be an independent predictor for CC (r=0.377, p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objectives: We investigated the presence of collateral circulation (CC) during early period of acute myocardial infarction (AMI) and evaluated its relationship with clinical, electrocardiographic, and angiographic parameters.Study design: In 79 patients (63 men, 16 women; mean age 57 years) who presented within the first six hours of AMI, coronary angiography was performed before primary angioplasty to determine the infarct-related artery (IRA), the number of arteries with significant stenosis (≥50%), localization of stenosis (proximal, middle, or distal), and the presence of CC. The presence of Q waves and reciprocal ST-segment changes were evaluated on initial electrocardiograms. Collateral circulation to the IRA was graded according to the Rentrop scoring system.Results: Collateral circulation to the IRA was detected in 31 patients (39.2%). Infarct-related artery was the left anterior descending (LAD) coronary artery in 43 patients (54.4%), circumflex (Cx) artery in 11 patients (13.9%), and the right coronary artery (RCA) in 25 patients (31.7%). On initial electrocardiograms, Q wave was absent in 34 patients (43%) and reciprocal ST-segment depression was present in 53 patients (67.1%). Collateral circulation was more common in RCA occlusions than those involving the LAD and Cx arteries (60%, 32.6%, and 18.2%, respectively; p=0.012). The presence of CC was significantly correlated with hypertension (r=0.226, p=0.045) and RCA occlusion (r=0.309, p=0.006). In multiple regression analysis, only RCA occlusion was found to be an independent predictor for CC (r=0.377, p

Özet

Amaç: Akut miyokard infarktüslü (AMİ) hastalarda erken dönem kollateral dolaşım (KD) varlığı araştırıldı ve bunun klinik, elektrokardiyografik ve anjiyografik parametrelerle ilişkisi değerlendirildi.Çalışma planı: Çalışmaya, ilk altı saat içinde başvuran AMİ’li 79 hasta (63 erkek, 16 kadın; ort. yaş 57) alındı. Primer anjiyoplasti öncesinde koroner anjiyografi ile infarktla ilişkili damar, anlamlı darlık (≥%50 darlık) saptanan damar sayısı, sorumlu damarda lezyonun yeri (proksimal, orta ve distal) ve KD varlığı kaydedildi. İnfarktla ilişkili damara KD’nin derecesi Rentrop sınıflamasına göre değerlendirildi. İlk altı saat içinde çekilen EKG’lerde Q dalgası varlığı ve resiprokal ST segment değişiklikleri belirlendi.Bulgular: Otuz bir hastada (%39.2) infarktla ilişkili damara KD görüldü. Sorumlu lezyon 43 hastada (%54.4) sol ön inen (LAD) koroner arter, 11’inde (%13.9) sirkumfleks (Cx) arter, 25’inde (%31.7) sağ koroner arterde (RCA) idi. İlk altı saat içindeki EKG’de, 34 hastada (%43) Q dalgası görülmedi; resiprokal ST segment çökmesine ise 53 hastada (%67.1) rastlandı. Kollateral dolaşım RCA tıkanmalarında, LAD ve Cx tıkanmalarına göre daha fazla görüldü (sırasıyla %60, %32.6 ve %18.2, p=0.012). Kollateral dolaşım varlığı ile hipertansiyon (r=0.226, p=0.045) ve RCA tıkanması (r=0.309, p=0.006) arasında anlamlı ilişki bulundu. Çokdeğişkenli regresyon analizinde, sadece RCA tıkanmasının KD varlığını öngörmede bağımsız belirleyici olduğu görüldü (r=0.377, p

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Cite This Article

ÖZDOĞRU, İ., SEYFELİ, E., SAĞLAM, H., ARINÇ, H., ERGİN, A., ÇİÇEK, Y., ABACI, A., YALÇIN, F. (2022). Evaluation of collateral circulation with clinical, electrocardiographic, and angiographic parameters in patients with acute myocardial infarction. Türk Kardiyoloji Derneği Arşivi, Cilt: 34 - Sayı: 1, 22–28. https://ajindex.com/articles/633718

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References (15)

  1. Leppo JA, O’Brien J, Rothendler JA, Getchell JD, Lee VW. Dipyridamole thallium-201 scintigraphy in the prediction of future cardiac events after acute myocardial infarction. N Engl J Med 1984;310:1014-8
  2. Moss AJ, Benhorin J. Prognosis and management after a first myocardial infarction. N Engl J Med 1990;322: 743-53
  3. Habib GB, Heibig J, Forman SA, Brown BG, Roberts R, Terrin ML, et al. Influence of coronary collateral vessels on myocardial infarct size in humans. Results of phase I thrombolysis in myocardial infarction (TIMI) trial. The TIMI Investigators. Circulation 1991; 83:739-46
  4. Hirai T, Fujita M, Nakajima H, Asanoi H, Yamanishi K, Ohno A, et al. Importance of collateral circulation for prevention of left ventricular aneurysm formation in acute myocardial infarction. Circulation 1989;79: 791-6
  5. Hansen JF. Coronary collateral circulation: clinical significance and influence on survival in patients with coronary artery occlusion. Am Heart J 1989; 117:290-5
  6. Meininger CJ, Schelling ME, Granger HJ. Adenosine and hypoxia stimulate proliferation and migration of endothelial cells. Am J Physiol 1988;255(3 Pt 2): H554-62
  7. Schaper W. Angiogenesis in the adult heart. Basic Res Cardiol 1991;86 Suppl 2:51-6
  8. Abaci A, Oguzhan A, Kahraman S, Eryol NK, Unal S, Arinc H, et al. Effect of diabetes mellitus on formation of coronary collateral vessels. Circulation 1999;99: 2239-42
  9. Kurotobi T, Sato H, Kinjo K, Nakatani D, Mizuno H, Shimizu M, et al. Reduced collateral circulation to the infarct-related artery in elderly patients with acute myocardial infarction. J Am Coll Cardiol 2004; 44:28-34
  10. Waltenberger J. Impaired collateral vessel development in diabetes: potential cellular mechanisms and therapeutic implications. Cardiovasc Res 2001;49: 554-60
  11. Sasayama S, Fujita M. Recent insights into coronary collateral circulation. Circulation 1992;85:1197-204
  12. Mason MJ, Walker SK, Patel DJ, Paul VE, Ilsley CD. Influence of clinical and angiographic factors on development of collateral channels. Coron Artery Dis 2000;11:573-8
  13. Rentrop KP, Cohen M, Blanke H, Phillips RA. Changes in collateral channel filling immediately after controlled coronary artery occlusion by an angioplasty balloon in human subjects. J Am Coll Cardiol 1985; 5:587-92
  14. Elayda MA, Mathur VS, Hall RJ, Massumi GA, Garcia E, de Castro CM. Collateral circulation in coronary artery disease. Am J Cardiol 1985;55:58-60
  15. Cohen MV. The functional value of coronary c