Journals / Türk Kardiyoloji Derneği Arşivi / 2015 / Cilt: 43 - Sayı: 1

Sol ventrikül geometrisi diyabetli hastalarda koroner akım rezervini etkiler

Left ventricle geometry affects coronary flow reserve in diabetic patients

Pages
49–57
Publication Date
2022-11-05
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Results: Compared with controls, CFR was decreased in dia- betic patients (p

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objectives: The aim of this study was to investigate the asso- ciation between coronary flow reserve (CFR) and left ventricle (LV) geometric patterns in patients with newly-diagnosed dia- betes mellitus (DM).
📊
Key Findings & Data:Study design: We studied 116 patients with newly-diagnosed DM and 31 healthy control subjects.
💡
Conclusion & Impact:Results: Compared with controls, CFR was decreased in dia- betic patients (p
🔬Design:Modeling & Simulation
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objectives: The aim of this study was to investigate the asso- ciation between coronary flow reserve (CFR) and left ventricle (LV) geometric patterns in patients with newly-diagnosed dia- betes mellitus (DM). Study design: We studied 116 patients with newly-diagnosed DM and 31 healthy control subjects. Echocardiographic ex- amination was performed on all subjects. Four different geo- metric patterns were identified in diabetic patients, according to LV mass index (LVMI) and relative wall thickness (RWT) [NG: Normal geometry; CR: Concentric remodeling; EH: Ec- centric hypertrophy; CH: Concentric hypertrophy]. CFR was calculated as the hyperemic to resting coronary diastolic peak velocities ratio. Results: Compared with controls, CFR was decreased in dia- betic patients (p

Özet

Amaç Bu çalışmamızda yeni diabetes mellitus tanısı konmuş hastalarda sol ventrikül geometrik paternleri ile koroner akım rezervi (KAR) arasındaki ilişkiyi değerlendirmeyi amaçladık.Çalışma planı Çalışmamıza yeni diabetes mellitus tanısı konmuş 116 hasta ile sağlıklı 31 olguluk kontrol grubu dahil edildi. Tüm hastalara ekokardiyografik değerlendirme yapıldı. Diyabetli hastalar sol ventrikül kitle indeksi ve göreceli duvar kalınlığına göre dört gruba ayrıldı (NG: Normal geometri; KR: Konsantrik remodelling; EH: Ekzantrik hipertrofi; KH: Konsantrik hipertrofi). KAR koroner hiperemik diyastolik en yüksek hızının istirahatteki en yüksek hıza oranı olarak hesaplandı.Bulgular Kontrol grubu ile kıyaslandığında diyabetli hasta grubunda KAR azalmış bulundu (p

🔖

Cite This Article

EKŞİ, F. H., OYTUN, A. B., ELBASAN, Z., ŞEN, Ö., KIRIM, S., ŞAHİN, D. Y., KULOĞLU, O., YÜKSEL, G. K., GÜR, M., ÇAYLI, M., UÇAR, H., ŞEKER, T. (2022). Sol ventrikül geometrisi diyabetli hastalarda koroner akım rezervini etkiler. Türk Kardiyoloji Derneği Arşivi, Cilt: 43 - Sayı: 1, 49–57. https://ajindex.com/articles/633512

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (13)

  1. Consensus development conference on the diagnosis of coronary heart disease in people with diabetes: 10-11 February 1998, Miami, Florida. American Diabetes Association. Diabetes Care 1998;21:1551-9
  2. Levy D, Garrison RJ, Savage DD, Kannel WB, Castelli WP. Prognostic implications of echocardiographically determined left ventricular mass in the Framingham Heart Study. N Engl J Med 1990;322:1561-6
  3. Gosse P. Left ventricular hypertrophy as a predictor of cardiovascular risk. J Hypertens Suppl 2005;23:27-33
  4. Fang ZY, Prins JB, Marwick TH. Diabetic cardiomyopathy: evidence, mechanisms, and therapeutic implications. Endocr Rev 2004;25:543-67
  5. Palmieri V, Tracy RP, Roman MJ, Liu JE, Best LG, Bella JN, et al. Relation of left ventricular hypertrophy to inflammation and albuminuria in adults with type 2 diabetes: the strong heart study. Diabetes Care 2003;26:2764-9
  6. Boudina S, Abel ED. Diabetic cardiomyopathy revisited. Circulation 2007;115:3213-23
  7. Dimitrow PP, Galderisi M, Rigo F. The non-invasive documentation of coronary microcirculation impairment: role of transthoracic echocardiography. Cardiovasc Ultrasound 2005;3:18
  8. Eroğlu S, Sade LE, Bozbaş H, Müderrisoğlu H. Decreased coronary flow reserve in obese women. Turk Kardiyol Dern Ars 2009;37:391-6
  9. Galderisi M, Capaldo B, Sidiropulos M, D’Errico A, Ferrara L, Turco A, et al. Determinants of reduction of coronary flow reserve in patients with type 2 diabetes mellitus or arterial hypertension without angiographically determined epicardial coronary stenosis. Am J Hypertens 2007;20:1283-90
  10. American Diabetes Association: Diagnosis and classification of diabetes mellitus. Diabetes Care 2011;34:62-9
  11. World Medical Association: Declaration of Helsinki—Ethical principles for medical research involving human subjects. 2011. Availableat: http: //www.wma.net/ en/30publications/ 10policies/ b3/index.html
  12. Lang RM, Bierig M, Devereux RB, Flachskampf FA, Foster E, Pellikka PA, et al. American Society of Echocardiography’s Nomenclature and Standards Committee; Task Force on Chamber Quantification; American College of Cardiology Echocardiography Committee; American Heart Association; European Association of Echocardiography, European Society of Cardiology. Recommendations for chamber quantification. Eur J Echocardiogr 2006;7:79-108
  13. European Society of Hypertension-European Society of Cardiology Guidelines Committee. 2003 European Society of Hypertension-European Society of Cardiology