Yüksek serum gama-glutamiltransferaz aktivitesi ile yavaş koroner akım arasındaki ilişki

Objective & Hypothesis:Objectives: We evaluated the relationship between coronary blood flow and serum gamma-glutamyltransferase(GGT) activity in patients with slow coronary flow (SCF).Study design: The study included 90 patients (47 men,43 women; mean age 50.8±9.4 years) with SCF and 88patients (45 men, 43 women; mean age 51.4±8.8 years)with coronary artery disease (CAD), whose diagnoses weremade by coronary angiography.

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Key Findings & Data:The resultswere compared with those of a control group consisting of86 age- and sex-matched patients who had normal coronaryarteries and normal coronary flow.

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Conclusion & Impact:The use of medi- cations was significantly more common in the CAD group(p

🔬Design:Research Article

📍Scope:Comprehensive Sample

⚙️Variables:Domain Parameters

Abstract

Objectives: We evaluated the relationship between coronary blood flow and serum gamma-glutamyltransferase(GGT) activity in patients with slow coronary flow (SCF).Study design: The study included 90 patients (47 men,43 women; mean age 50.8±9.4 years) with SCF and 88patients (45 men, 43 women; mean age 51.4±8.8 years)with coronary artery disease (CAD), whose diagnoses weremade by coronary angiography. Patients with CAD had nor- mal coronary flow. Coronary flow was quantified using thecorrected TIMI frame count (TFC) method and serum levelsof gamma-glutamyltransferase were measured. The resultswere compared with those of a control group consisting of86 age- and sex-matched patients who had normal coronaryarteries and normal coronary flow. Results: The three groups were similar with respect tobody mass index, presence of hypertension and diabetesmellitus, lipid profiles, and fasting glucose. The use of medi- cations was significantly more common in the CAD group(p

Özet

Amaç: Çalışmamızda yavaş koroner kan akımı (YKA) olan hastalarda serum gama-glutamiltransferaz (GGT) aktivitesi ile koroner kan akımı arasındaki ilişki araştırıldı. Çalışma planı: Çalışmaya YKA saptanan 90 hasta (47 erkek, 43 kadın; ort. yaş 50.8±9.4) ve koroner arter hastalığı (KAH) olan 88 hasta (45 erkek, 43 kadın; ort. yaş 50.8±9.4) alındı. Yavaş koroner kan akımı ve KAH tanıları koroner anjiyografi ile kondu. Koroner arter hastalığı olan grupta normal koroner akım vardı. Tüm hastalarda koroner akım düzeltilmiş TIMI kare sayısı ile değerlendirildi ve serum GGT düzeyleri ölçüldü. Sonuçlar, yaş ve cinsiyet uyumlu ve koroner arterleri ve koroner akımı normal bulunan 86 hastadan oluşan kontrol grubuyla karşılaştırıldı. Bulgular: Gruplar arasında beden kütle indeksi, hipertansiyon ve diyabet varlığı, lipit profili ve açlık kan şekeri açısından fark yoktu. Koroner arter hastalığı olan grupta ilaç kullanımı anlamlı derecede fazlaydı (p

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Cite This Article

MADEN, O., DEMİR, A. D., BAŞAR, N., ÖZLÜ, M. F., GÜNGÖR, Ö., MALÇOK, Ö., ERBAY, A. R., ÖZCAN, F., ŞEN, N., TURAK, O., ÇAĞLI, K. (2022). Yüksek serum gama-glutamiltransferaz aktivitesi ile yavaş koroner akım arasındaki ilişki. Türk Kardiyoloji Derneği Arşivi, Cilt: 37 - Sayı: 3, 168–173. https://ajindex.com/articles/633372

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