Journals / Ankara Üniversitesi Tıp Fakültesi Mecmuası / 2021 / Cilt: 74 - Sayı: 1

The Relationship Between Monocyte/HDL Cholesterol Ratio and Clinical Outcomes in Acute Myocarditis Patients

Akut Miyokardit Hastalarında Monosit/HDL Kolestrol Oranı ile Klinik Sonlanımlar Arasındaki İlişki

Pages
76–82
Publication Date
2022-10-10
DOI
—
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

Results: High C-reactive protein level, low high density lipoprotein cholesterol and glucose levels, and low ejection fraction were found in patients with clinical endpoints. (p

📌 3 Key Takeaways

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Objective & Hypothesis:Objectives: Myocarditis is an inflammatory disease of the heart muscle.
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Key Findings & Data:Materials and Methods: Between March 2009 and March 2017, 156 consecutive patients who underwent cardiac magnetic resonance with the diagnosis of acute myocarditis were included in the study.
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Conclusion & Impact:Results: High C-reactive protein level, low high density lipoprotein cholesterol and glucose levels, and low ejection fraction were found in patients with clinical endpoints. (p
🔬Design:Research Article
📍Scope:2009 Verileri
⚙️Variables:Domain Parameters

Abstract

Objectives: Myocarditis is an inflammatory disease of the heart muscle. Inflammation and oxidative stress are known to play an important role in myocarditis pathogenesis. The aim of this study is to evaluate the relationship between clinical endpoints and monocyte/high-density lipoprotein (HDL) ratio in acute myocarditis patients. Materials and Methods: Between March 2009 and March 2017, 156 consecutive patients who underwent cardiac magnetic resonance with the diagnosis of acute myocarditis were included in the study. The patients were divided into two groups according to clinical endpoints. The clinical endpoint was defined as malignant arrhythmia, cardiovascular death during follow-up, and new-onset heart failure. Results: High C-reactive protein level, low high density lipoprotein cholesterol and glucose levels, and low ejection fraction were found in patients with clinical endpoints. (p

Özet

Amaç: Miyokardit, kalp kasının enflamatuvar bir hastalığıdır. Enflamasyon ve oksidatif stresin miyokardit patogenezinde önemli bir rol oynadığı bilinmektedir. Bu çalışmanın amacı akut miyokardit hastalarında klinik sonlanım noktaları ile monosit/yüksek yoğunluklu lipoprotein (HDL) oranı arasında ilişkininin değerlendirilmesidir. Gereç ve Yöntem: Mart 2009-Mart 2017 yılları arasında, akut miyokardit tanısı ile kardiyak manyetik rezonans çekilen ardışık 156 hasta çalışmaya alındı. Hastalar klinik sonlanım noktalarına göre ikiye ayrıldı. Klinik sonlanım noktası malign aritmi, takip süresince kardiyovasküler ölüm gerçekleşmesi ve yeni başlangıçlı kalp yetmezliği olarak tanımlandı. Bulgular: Klinik sonlanım izlenen hastalarda yüksek C-reaktif protein seviyesi, düşük yüksek yoğunluklu lipoprotein kolesterol ve glukoz değerleri, azalmış ejeksiyon fraksiyonu izlendi (hepsi için p

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Cite This Article

KARAASLAN, Ö. Ç., EKİZLER, F. A., ÖZİLHAN, M. O., ÇOTELİ, C., ÜNAL, S., MADEN, O. (2022). The Relationship Between Monocyte/HDL Cholesterol Ratio and Clinical Outcomes in Acute Myocarditis Patients. Ankara Üniversitesi Tıp Fakültesi Mecmuası, Cilt: 74 - Sayı: 1, 76–82. https://ajindex.com/articles/443476

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