Journals / Türk Kardiyoloji Derneği Arşivi / 2010 / Cilt: 38 - Sayı: 2

Güneydoğu Anadolu Bölgesi'nde üçüncü basamak bir hastanede enfektif endokarditin epidemiyolojik, klinik ve mikrobiyolojik özellikleri

Epidemiological, clinical and microbiological profile of infective endocarditis in a tertiary hospital in the South-East Anatolia Region

Pages
107–111
Publication Date
2022-11-05
DOI
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Conclusion: Our data reflect epidemiological, clinical, and microbiological profile of IE in a tertiary hospital located in the Southeastern Anatolia.

📌 3 Key Takeaways

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Objective & Hypothesis:Objectives: We aimed to evaluate epidemiological, clinical, and microbiological features of infective endocarditis (IE) in a tertiary university hospital.
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Key Findings & Data:Study design: The study included 72 patients (31 women, 41 men; mean age 45±16 years; range 18 to 80 years) who were diagnosed as having definite IE, according to the modified Duke criteria, between 2004 and 2007.
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Conclusion & Impact:Conclusion: Our data reflect epidemiological, clinical, and microbiological profile of IE in a tertiary hospital located in the Southeastern Anatolia.
🔬Design:Review & Systematic Survey
📍Scope:2004 Verileri
⚙️Variables:Domain Parameters

Abstract

Objectives: We aimed to evaluate epidemiological, clinical, and microbiological features of infective endocarditis (IE) in a tertiary university hospital. Study design: The study included 72 patients (31 women, 41 men; mean age 45±16 years; range 18 to 80 years) who were diagnosed as having definite IE, according to the modified Duke criteria, between 2004 and 2007. Data were reviewed on age, sex, underlying heart disease, predisposing conditions for bacteremia, echocardiographic and microbiological findings, treatment, complications, and mortality. Results: Infective endocarditis developed on a native valve in 47 (65.3%), a mechanical prosthetic valve in 21 (29.2%), and a pacemaker in two cases. The location of IE could not be determined in two cases (2.8%). Rheumatic heart disease (36.1%) was the most common preexisting valvular abnormality. The mitral valve was the most commonly affected valve in both native valves (43.1%) and prosthetic valves (13.9%). The most frequent symptom was fever (n=60, 83.3%). Electrocardiography showed abnormal findings in 24 cases (33.3%). Transthoracic and/or transesophageal echocardiography showed a vegetation in 63 cases (87.5%), moderate or severe mitral regurgitation in 41 cases (56.9%), aortic regurgitation in 21 cases (29.2%), and tricuspid regurgitation in 29 cases (40.3%). Staphylococci (26.4%) and streptococci (22.2%) were the most common causative agents. Cultures were negative in 26 cases (36.1%). Twenty patients (27.8%) underwent surgical treatment. Congestive heart failure (n=23, 31.9%) and cerebrovascular accidents (n=10, 13.9%) were the major complications. In-hospital mortality occurred in 11 cases (15.3%). Conclusion: Our data reflect epidemiological, clinical, and microbiological profile of IE in a tertiary hospital located in the Southeastern Anatolia.

Özet

Amaç: Üçüncü basamak üniversite hastanemizde enfektif endokarditin (EE) epidemiyolojik, klinik ve mikrobiyolojik özelliklerinin belirlenmesi amaçlandı. Çalışma planı: Çalışmada, 2004-2007 yılları arasında, modifiye Duke ölçütlerine göre kesin EE tanısı konan 72 hasta (31 kadın, 41 erkek; ort. yaş 45±16; dağılım 18-80) incelendi. Hastaların, yaş, cinsiyet, altta yatan kalp hastalığı, bakteremiye zemin hazırlayan etkenler, ekokardiyografik ve mikrobiyolojik bulgular, tedavi, komplikasyon ve mortalite ile ilgili bilgileri değerlendirildi. Bulgular: Enfektif endokardit 47 hastada (%65.3) doğal kapakta, 21 hastada (%29.2) mekanik protez kapakta, iki hastada (%2.8) kalp pili üzerinde saptandı. İki hastada (%2.8) enfeksiyonun yeri belirlenemedi. Romatizmal kalp hastalığı (%36.1) en yaygın kapak patolojisiydi. Hem doğal kapaklarda (%43.1) hem de prostatik kapaklarda (%13.9) en sık etkilenen kapak mitral kapak idi. En yaygın semptom ateş (n=60, %83.3) idi. Yirmi dört hastanın (%33.3) elektrokardiyografisinde anormal bulguya rastlandı. Transtorasik ve/veya transözofageal ekokardiyografide 63 olguda (%87.5) vejetasyon, 41 olguda (%56.9) orta-ciddi derecede mitral yetersizliği, 21 olguda (%29.2) aort yetersizliği, 29 olguda (%40.3) triküspit yetersizliği saptandı. Kültürlerde etken mikroorganizma olarak en sık stafilokok (%26.4) ve streptokok (%22.2) üredi; 26 olgunun kültürlerinde (%36.1) üreme olmadı. Yirmi hastaya (%27.8) cerrahi tedavi uygulandı. Ana komplikasyon olarak en sık konjestif kalp yetersizliği (n=23, %31.9) ve serebrovasküler olay (n=10, %13.9) görüldü. Hastane içi ölüm 11 olguda (%15.3) meydana geldi. Sonuç: Bulgularımız Güneydoğu Anadolu Bölgesi’nde üçüncü basamak bir hastanede EE’nin epidemiyolojik, klinik ve mikrobiyolojik özelliklerini yansıtmaktadır.

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Cite This Article

SUCU, M., AKSOY, M., DAVUTOĞLU, V., ÖZER, O. (2022). Güneydoğu Anadolu Bölgesi'nde üçüncü basamak bir hastanede enfektif endokarditin epidemiyolojik, klinik ve mikrobiyolojik özellikleri. Türk Kardiyoloji Derneği Arşivi, Cilt: 38 - Sayı: 2, 107–111. https://ajindex.com/articles/633254

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