Journals / Türk Kardiyoloji Derneği Arşivi / 2012 / Cilt: 40 - Sayı: 7

A case of acute coronary syndrome following the use of parenteral penicillin: Kounis syndrome

Parenteral penisilin kullanımını takiben gelişen akut koroner sendrom olgusu: Kounis sendromu

Pages
615–619
Publication Date
2022-11-05
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

With this report, we remind clinicians to consider Kounis syndrome in patients who are subjected to allergenic substances and demonstrate acute chest pain.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Kounis syndrome refers to the concurrence of acute coronary events and allergic or hypersensitivity reactions.
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Key Findings & Data:A 52-year-old male patient had chest pain, hypotension and ST-elevation on leads DI and aVL of electrocardiography 30 minutes after intramuscular penicillin injection due to cryptic tonsillitis.
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Conclusion & Impact:With this report, we remind clinicians to consider Kounis syndrome in patients who are subjected to allergenic substances and demonstrate acute chest pain.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Kounis syndrome refers to the concurrence of acute coronary events and allergic or hypersensitivity reactions. In this report, we describe the case of a male patient, in whom acute ST-segment elevation and myocardial infarction developed immediately after injection of depot penicillin, and we discuss the Kounis syndrome. A 52-year-old male patient had chest pain, hypotension and ST-elevation on leads DI and aVL of electrocardiography 30 minutes after intramuscular penicillin injection due to cryptic tonsillitis. Kounis syndrome was considered as a possible diagnosis according to the presentation. Histamine and tryptase levels were not studied due to the delay on arrival to the emergency department. The patient promptly underwent coronary angiography, which revealed only diffuse plaques in all main coronary arteries without any obstructive lesion. We found only increased immunoglobulin (Ig) E, which is associated with the syndrome. With this report, we remind clinicians to consider Kounis syndrome in patients who are subjected to allergenic substances and demonstrate acute chest pain.

Özet

Kounis sendromu hipersensitive veya alerjik reaksiyonlarla birlikte görülen akut koroner olayları tanımlamaktadır. Bu yazıda, depo penisilin enjeksiyonundan hemen sonra akut ST-segment yükselmeli miyokart enfarktüsü gelişen bir olgu sunuldu ve Kounis sendromu tartışıldı. Elli iki yaşında bir erkek hastada kriptik tonsillit tanısı ile yapılan intramüsküler penisilin enjeksiyonundan 30 dakika sonra şiddetli retrosternal göğüs ağrısı, hipotansiyon ve elektrokardiyografide DI ve aVLde ST-segment yükselmesi saptandı. Hastada muhtemel tanı olarak Kounis sendromu düşünüldü. Acil servise geç başvuru nedeniyle histamin ve triptaz düzeyi bakılamamış, tanı testlerinden sadece immünglobülin (Ig) E antikor düzeyi yüksek bulunmuştu. Koroner anjiyografide yaygın, tıkayıcı olmayan koroner arter hastalığı tespit edildi. Alerji nedeni olabilecek etkenlerle karşı karşıya kalmanın ardından alerji reaksiyonu ile birlikte göğüs ağrısı gelişen olgularda Kounis sendromu da düşünülmelidir.

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Cite This Article

ŞENTÜRK, B., GÖLBAŞI, Z., TOK, D., ÖZCAN, F. (2022). A case of acute coronary syndrome following the use of parenteral penicillin: Kounis syndrome. Türk Kardiyoloji Derneği Arşivi, Cilt: 40 - Sayı: 7, 615–619. https://ajindex.com/articles/633031

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