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Journals / Türk Kardiyoloji Derneği Arşivi / 2012 / Cilt: 40 - Sayı: 7

Hipertansiyonlu hastalarda sol ventrikülün eş zamanlı kasılmasını etkileyen faktörler: Arteriyel katılık ve merkezi kan basıncı etkili mi?

Factors affecting left ventricular synchronicity in hypertensive patients: are arterial stiffness and central blood pressures influential?

Kayıhan KARAMAN
Merih KUTLU
Mürsel ŞAHİN
Ömer GEDİKLİ
Gülhanım KIRIŞ
Zeynep KAZAZ
Abdulkadir KIRIŞ
Şahin KAPLAN
Asım ÖREM
Pages
581–588
Publication Date
2022-11-05
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The standart deviation of Ts of 12 LV segments in patients with hypertension and the controls were 48.7±18.8 vs. 25.8±13.1, respectively (p

📌 3 Key Takeaways

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Objective & Hypothesis:Objectives: Left ventricular (LV) dyssynchrony is a common finding in patients with hypertension and is associated with LV hypertrophy.
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Key Findings & Data:Arterial stiffness (AS) and central (aortic) blood pressures play a significant role in end-organ damage such as LV hypertrophy caused by hypertension.
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Conclusion & Impact:The standart deviation of Ts of 12 LV segments in patients with hypertension and the controls were 48.7±18.8 vs. 25.8±13.1, respectively (p
🔬Design:Modeling & Simulation
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objectives: Left ventricular (LV) dyssynchrony is a common finding in patients with hypertension and is associated with LV hypertrophy. Arterial stiffness (AS) and central (aortic) blood pressures play a significant role in end-organ damage such as LV hypertrophy caused by hypertension. The objective of this study was to investigate the relationship between AS, central blood pressures (BP) and LV dyssynchrony. Study design: Thirty-five newly diagnosed hypertensive patients and 40 controls were enrolled in the study. The entire study population underwent a comprehensive echocardiographic study including tissue synchrony imaging. The 12 segmental model was used to measure the time to regional peak systolic tissue velocity (Ts) in the LV and two dyssynchrony indices were computed. Parameters of AS including pulse wave velocity (PWV), augmentation index (AIx@75), and central systolic and diastolic BP were evaluated by applanation tonometry. Results: The baseline clinical and echocardiographic parameters of both groups were similar except for their BPs. Dyssynchrony indices were prolonged in patients with hypertension as compared to the controls. The standart deviation of Ts of 12 LV segments in patients with hypertension and the controls were 48.7±18.8 vs. 25.8±13.1, respectively (p

Özet

Amaç: Sol ventrikül (SV) eş zamanlı kasılma bozukluğu hipertansiyonlu hastalarda sık rastlanılan bir bulgu olup SV hipertrofisi ile ilişkilidir. Arteriyel katılık (AK) ve merkezi (aortik) kan basıncı, SV hipertrofisi gibi hipertansiyon kaynaklı hedef organ hasarında önemli rol oynar. Bu çalışmada, AK, merkezi sistolik ve diyastolik kan basınçları (KB) ve SV senkronizasyon bozukluğu arasındaki ilişki incelendi. Çalışma planı: Yeni hipertansiyon tanısı konmuş 35 hasta ve 40 kontrol çalışmaya alındı. Tüm çalışma popülasyonuna doku senkronizasyon görüntülemesini (DSG) de içeren kapsamlı ekokardiyografik inceleme yapıldı. SVnin pik sistolik doku hız zamanı (Zs) 12 segment modeli ile ölçüldü ve iki eş zamanlı kasılma bozukluğu indeksi hesaplandı. Nabız dalga hızı (NDH) ve artış indeksini (AIx@75) içeren AK parametreleri ile merkezil sistolik ve diyastolik KB aplanasyon tonometresi ile değerlendirildi. Bulgular: Kan basınçları dışında her iki grubun temel klinik ve ekokardiyografik parametreleri benzerdi. Eş zamanlı kasılma bozukluğu indeksleri hipertansiyonlu hastalarda kontrol grubuna göre uzamıştı: 12 segmentin Zsnın standart sapması (48.7±18.8 ve 25.8±13.1, p

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Cite This Article

KARAMAN, K., KUTLU, M., ŞAHİN, M., GEDİKLİ, Ö., KIRIŞ, G., KAZAZ, Z., KIRIŞ, A., KAPLAN, Ş., ÖREM, A. (2022). Hipertansiyonlu hastalarda sol ventrikülün eş zamanlı kasılmasını etkileyen faktörler: Arteriyel katılık ve merkezi kan basıncı etkili mi?. Türk Kardiyoloji Derneği Arşivi, Cilt: 40 - Sayı: 7, 581–588. https://ajindex.com/articles/633011

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