Journals / Türk Kardiyoloji Derneği Arşivi / 2014 / Cilt: 42 - Sayı: 5

Mekanik triküspit protez kapak trombozunun seri floroskopi klavuzluğunda düşük doz doku plazminojen aktivatörünün çok yavaş infüzyonu ile tedavisi

A serial fluoroscopy-guided thrombolytic therapy of a mechanical tricuspid prosthetic valve thrombosis with low-dose and ultra-slow infusion of tissue-type plasminogen activator

Pages
478–481
Publication Date
2022-11-05
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Herein, we report a case of tricuspid valve thrombosis who was managed with low-dose (25 mg) and ultra-slow (25 hours) infusion of tissue-type plasminogen activator under the guidance of serial fluoroscopy.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Prosthetic valve thrombosis is a life-threatening complication that is seen most commonly in patients with left-sided prosthetic valves.
📊
Key Findings & Data:However, mechanical tricuspid valves carry the highest risk of thrombosis of any cardiac valve.
💡
Conclusion & Impact:Herein, we report a case of tricuspid valve thrombosis who was managed with low-dose (25 mg) and ultra-slow (25 hours) infusion of tissue-type plasminogen activator under the guidance of serial fluoroscopy.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Prosthetic valve thrombosis is a life-threatening complication that is seen most commonly in patients with left-sided prosthetic valves. However, mechanical tricuspid valves carry the highest risk of thrombosis of any cardiac valve. Thrombolysis has been performed successfully in right-sided prosthetic valve thrombosis and has been rec- ommended as the first-line treatment in these patients. Al- though two-dimensional and real-time three-dimensional transesophageal echocardiography are the gold standard imaging modalities for the diagnosis of prosthetic valve thrombosis, right-sided prosthetic valves may not be evalu- ated precisely. This is a serious problem during the follow- up of patients who receive thrombolytic therapy for tricuspid valve thrombosis. Fluoroscopy is an alternative noninvasive imaging method that provides valuable information about leaflet motion and may be used for such cases with re- stricted leaflets. Herein, we report a case of tricuspid valve thrombosis who was managed with low-dose (25 mg) and ultra-slow (25 hours) infusion of tissue-type plasminogen activator under the guidance of serial fluoroscopy.

Özet

Protez kapak trombozu daha çok sol taraf protez kapağı olan hastalarda gözlenen hayatı tehdit edici bir komplikasyondur. Halbuki mekanik triküspit kapaklar diğer kapaklara göre daha yüksek tromboz riski taşımaktadır. Trombolitik tedavi sağ taraf protez kapak trombozlarının tedavisinde başarılı olarak uygulanmakta ve bu hastalar için ilk tercih tedavi yöntemi olarak önerilmektedir. İki boyutlu ve gerçek zamanlı üç boyutlu transözofajiyal ekokardiyografi protez kapak trombozu tanısında altın standart olmasına rağmen, sağ taraf protez kapakları yeterli derecede görüntülenemeyebilir. Bu durum triküspit kapak trombozu nedeniyle trombolitik tedavi uygulanan hastaların takibinde ciddi bir sorun oluşturur. Floroskopi kapak hareketleri hakkında değerli bilgiler sunan alternatif bir non-invaziv görüntüleme yöntemidir ve kapak kısıtlılığı bulunan bu tür hastalarda kullanılabilir. Bu yazıda, seri floroskopi klavuzluğunda düşük doz (25 mg) doku plazminojen aktivatörünün çok yavaş (25 saat) infüzyonu ile tedavi edilen triküspit kapak trombozlu olgu sunuldu.

🔖

Cite This Article

ASTARCIOĞLU, M. A., ÖZKAN, M., KALÇIK, M., GÜRSOY, O. M. (2022). Mekanik triküspit protez kapak trombozunun seri floroskopi klavuzluğunda düşük doz doku plazminojen aktivatörünün çok yavaş infüzyonu ile tedavisi. Türk Kardiyoloji Derneği Arşivi, Cilt: 42 - Sayı: 5, 478–481. https://ajindex.com/articles/632817

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (11)

  1. Özkan M, Çakal B, Karakoyun S, Gürsoy OM, Çevik C, Kalçık M, et al. Thrombolytic therapy for the treatment of prosthetic heart valve thrombosis in pregnancy with lowdose, slow infusion of tissue-type plasminogen activator. Circulation 2013
  2. CrossRef 2. Özkan M, Gündüz S, Biteker M, Astarcioglu MA, Çevik C, Kaynak E, et al. Comparison of different TEE-guided thrombolytic regimens for prosthetic valve thrombosis: the TROIA trial. JACC Cardiovasc Imaging 2013
  3. CrossRef 3. Shapira Y, Sagie A, Jortner R, Adler Y, Hirsch R. Thrombosis of bileaflet tricuspid valve prosthesis: clinical spectrum and the role of nonsurgical treatment. Am Heart J 1999
  4. CrossRef 4. Montorsi P, Arena V, Muratori M, Lavarra F, Cavoretto D, Repossini A, et al. Fluoroscopic functional evaluation of bileaflet prostheses: effect of different intraoperative valve orientation. Am J Card Imaging 1996
  5. Montorsi P, De Bernardi F, Muratori M, Cavoretto D, Pepi M. Role of cine-fluoroscopy, transthoracic, and transesophageal echocardiography in patients with suspected prosthetic heart valve thrombosis. Am J Cardiol 2000
  6. CrossRef 6. Luluaga IT, Carrera D, D’Oliveira J, Cantaluppi CG, Santin H, Molteni L, et al. Successful thrombolytic therapy after acute tricuspid-valve obstruction. Lancet 1971
  7. CrossRef 7. Thorburn CW, Morgan JJ, Shanahan MX, Chang VP. Longterm results of tricuspid valve replacement and the problem of prosthetic valve thrombosis. Am J Cardiol 1983
  8. Montorsi P, Cavoretto D, Ballerini G. Thrombosis of mechanical heart valve prostheses: revisiting the role of fluoroscopy. Br J Radiol 2000
  9. CrossRef 9. Muratori M, Montorsi P, Maffessanti F, Teruzzi G, Zoghbi WA, Gripari P, et al. Dysfunction of bileaflet aortic prosthesis: accuracy of echocardiography versus fluoroscopy. JACC Cardiovasc Imaging 2013
  10. CrossRef 10. Montorsi P, Cavoretto D, Alimento M, Muratori M, Pepi M. Prosthetic mitral valve thrombosis: can fluoroscopy predict the efficacy of thrombolytic treatment? Circulation 2003
  11. 108 Suppl 1:II79-84. CrossRef