Journals / Türk Kardiyoloji Derneği Arşivi / 2015 / Cilt: 43 - Sayı: 7

Kararlı koroner arter hastalarında kalp hızı türbülansı ile koroner arter hastalığının ciddiyeti arasındaki ilişki

Heart rate turbulence in patients with stable coronary artery disease and its relationship with the severity of the disease

Pages
594–598
Publication Date
2022-11-05
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

Conclusion: The study demonstrated that HRT variables areimpaired in patients with stable CAD when compared to thosein the control group, and that these variables also correlatewith severity of CAD.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: Heart rate turbulence (HRT) indicates the impair- ment of cardiac autonomic function.
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Key Findings & Data:Methods: The study included 58 patients (mean age:58.9±10.0 years; 25 male) with documented CAD anddemonstrating ventricular premature complexes on Holtermonitoring, and a control group of 52 patients (mean age:55.9±9.3 years; 36 male) with no history of CAD and dem- onstrating ventricular premature complexes.
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Conclusion & Impact:Conclusion: The study demonstrated that HRT variables areimpaired in patients with stable CAD when compared to thosein the control group, and that these variables also correlatewith severity of CAD.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: Heart rate turbulence (HRT) indicates the impair- ment of cardiac autonomic function. With the literature con- taining insufficient information on HRT in stable coronary ar- tery disease (CAD), this study aimed to investigate the role ofHRT in patients with stable CAD. Methods: The study included 58 patients (mean age:58.9±10.0 years; 25 male) with documented CAD anddemonstrating ventricular premature complexes on Holtermonitoring, and a control group of 52 patients (mean age:55.9±9.3 years; 36 male) with no history of CAD and dem- onstrating ventricular premature complexes. HRT param- eters such as turbulence onset (TO) and slope (TS) wereanalyzed. Angiographic Gensini score were used to evaluateCAD severity. Results: There was a significant difference in HRT param- eters between the 2 groups. TO: 0.47±1.52% vs. -1.61±2.0%(p=0.001) and TS: 4.7±3.0 vs. 6.4±3.7 ms/RR (p=0.009) in pa- tients with CAD and control group respectively. Given also thatTO ≥0% and TS ≤2.5 ms/ RR values are considered abnormal,there was significant difference between the two groups; TOabnormal: 27 patients (46.6%) vs. 7 patients (13.5%), p=0.001,and TS abnormal: 15 patients (25.9%) vs. 4 patients (7.7%),(p=0.004) in CAD patients and control group respectively. Apositive correlation was detected between TO and Gensiniscore (r=0.282, p=0.001) and a negative correlation detectedbetween TS and Gensini score (r=-0.287, p=0.001). Conclusion: The study demonstrated that HRT variables areimpaired in patients with stable CAD when compared to thosein the control group, and that these variables also correlatewith severity of CAD.

Özet

Amaç: Kalp hızı türbülansı (KHT) ventriküler erken atımlara(VEA) yanıt olarak sinüs ritmi siklüsündeki fizyolojik değişim- leri ifade eder ve anormal değerlerinin mortalite artışı ile iligiliolduğu saptanmıştır. Çalışmamızda koroner arter hastalığın- da (KAH) KHT parametrelerini ve KAHnin ciddiyeti ile arasın- daki ilişkiyi araştırmayı amaçladık. Yöntemler: Çalışmamıza Holter incelemesinde VEA saptan- mış, KAH olan 58 hasta (ortalama 58.9±10.0 yıl; 25 erkek) ile kontrol grubu olarak koroner anjiyografide normal koronerarterler saptanan 52 olgu (ortalama yaş: 55.9±9.3 yaş; 36 er- kek) alındı. Yirmi dört saatlik Holter kayıtlarından KHT para- metreleri olan türbülans başlangıcı (TB), türbülans eğimi (TE)hesaplandı. Koroner arter hastalığının ciddiyeti Gensini skoruile değerlendirildi. Bulgular: İki grup arasında KHT parametreleri arasındaanlamlı fark saptandı (sırasıyla, KAH ve kontrol grubu; TB:-%0.47±1.52 ve -%1.61±2.0, p=0.001; TE: 4.7±3.0 ve 6.4±3.7ms/RR, p=0.009 TB), ayrıca TB ≥%0 ve TE ≤2.5 ms/RR de- ğerleri patolojik olarak alındığında da KAH grubunda KHT pa- rametreleri anlamlı olarak patolojik saptandı (sırasıyla, KAHve kontrol grubu; TB anormal: 27 (%46.6) hasta ve 7 (%13.5)hasta, p=0.001; TE anormal: 15 (%25.9) hasta ve 4 (%7.7)hasta, p=0.004). Türbülans başlangıcı ile Gensini skoru ara- sında pozitif korelasyon (r=0.282, p=0.001) ve TE değerle- riyle Gensini skoru arasında negatif korelasyon (r=-0.287,p=0.001) saptandı. Sonuç: Çalışmamızda KHT parametreleri KAH grubunda,kontrol gurnuna göre anlamlı olarak patolojik saptandı. Ayrı- ca KHT parametreleriyle KAH ciddiyeti arasında korelasyonbulundu.

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Cite This Article

SİNAN, Ü. Y., OKTAY, V., COŞKUN, U., FIRATLI, İ., GÜRMEN, T., YILDIZ, A., ABACI, O., BAYDAR, O. (2022). Kararlı koroner arter hastalarında kalp hızı türbülansı ile koroner arter hastalığının ciddiyeti arasındaki ilişki. Türk Kardiyoloji Derneği Arşivi, Cilt: 43 - Sayı: 7, 594–598. https://ajindex.com/articles/632631

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