Journals / Türk Kardiyoloji Derneği Arşivi / 2018 / Cilt: 46 - Sayı: 2

Heparin-induced thrombocytopenia after MitraClip: A case report

MitraClip sonrası heparinin tetiklediği trombositopeni: Olgu sunumu

Pages
136–139
Publication Date
2022-11-05
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The decision about continuation or cessationof heparin therapy is an important cornerstone for hospitalized patients with HIT.

📌 3 Key Takeaways

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Objective & Hypothesis:Heparin-induced thrombocytopenia (HIT) andheparin-induced thrombocytopenia and thrombosis are potentially fatal adverse reactions to heparin therapy causedby the formation of polyclonal antibodies against the plateletfactor 4-heparin complex.
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Key Findings & Data:Fatal limb and organ damage ordeath may occur as a result of this immunological drug reaction.
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Conclusion & Impact:The decision about continuation or cessationof heparin therapy is an important cornerstone for hospitalized patients with HIT.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Heparin-induced thrombocytopenia (HIT) andheparin-induced thrombocytopenia and thrombosis are potentially fatal adverse reactions to heparin therapy causedby the formation of polyclonal antibodies against the plateletfactor 4-heparin complex. Fatal limb and organ damage ordeath may occur as a result of this immunological drug reaction. Described in this case report is the management of apatient who developed HIT after undergoing a MitraClip transcatheter mitral valve repair. The aim was to encourage clinicians to pay special attention to a frail patient who receivesheparin therapy and to advise clinicians that clinical scoresand laboratory tests should be used as a complement for certain diagnosis. The decision about continuation or cessationof heparin therapy is an important cornerstone for hospitalized patients with HIT.

Özet

Heparinin tetiklediği trombositopeni (HTT) ve tromboz (HTTT), platelet faktör 4 (PF4)-heparin komplekslerine karşı oluşan antikorların oluşumu ile tetiklenen ölümcül bir heparin yan etkisidir. Bu immünolojik ilaç reaksiyonu hayatı tehdit eden ekstremite ve organ hasarları ile ölüme neden olabilir. Bu olgu sunumu ile MitraClip transkateter mitral kapak tamiri sonrası heparinin tetiklediği trombositopeni gelişen bir hastanın yönetimini sunmaktayız. Olgu sunumumuz ile klinikçilere, düşkün hastalarda heparin tedavisi kullanırken dikkatli olmalarını ve hastanede yatan hastaların tedavisinde önemli bir köşe taşı olan heparinin kesilmesi ya da devam edilmesi kararı verilirken klinik skorlama sistemleri ve laboratuvar testlerini tamamlayıcı olarak kullanmalarını hatırlatmayı amaçladık.

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Cite This Article

ÇELİKER, C., ÇETİNARSLAN, Ö., ÖKÇÜN, E. B., GÜLTEKİN, N. N., SİNAN, Ü. Y. (2022). Heparin-induced thrombocytopenia after MitraClip: A case report. Türk Kardiyoloji Derneği Arşivi, Cilt: 46 - Sayı: 2, 136–139. https://ajindex.com/articles/632126

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