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Journals / Türk Kardiyoloji Derneği Arşivi / 2015 / Cilt: 43 - Sayı: 8

Yeni tanı konmuş hipertansiyonlu hastalarda epikardiyal yağ kalınlığının sol ventrikül miyokart performansı ile ilişkisi

Epicardial fat thickness as associated with left ventricular myocardial performance in patients with newly diagnosed hypertension

Zafer ELBASAN
Ayşe UÇAR KALYONCU
Hazar HARBALIOĞLU
Mustafa GÜR
Murat ÇAYLI
Hakan UÇAR
Taner ŞEKER
Abdurrezzak BÖREKÇİ
Ahmet Oytun BAYKAN
Pages
705–713
Publication Date
2022-11-05
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Results: EFth values of the TD-MPIhigh group were higherthan those of the TD-MPIlow group (p

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objective: Epicardial fat thickness (EFth) is associated withboth left ventricular hypertrophy (LVH) and diastolic dysfunc- tion.
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Key Findings & Data:However, the effect of EFth on myocardial performanceis not known.
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Conclusion & Impact:Results: EFth values of the TD-MPIhigh group were higherthan those of the TD-MPIlow group (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: Epicardial fat thickness (EFth) is associated withboth left ventricular hypertrophy (LVH) and diastolic dysfunc- tion. However, the effect of EFth on myocardial performanceis not known. The aim of this study was to investigate the re- lationship between EFth and tissue Doppler myocardial per- formance index (TD-MPI), which incorporates both systolicand diastolic left ventricular (LV) function, in newly diagnosedhypertension (HT) patients. Methods: A total of 314 consecutive, newly diagnosed HT pa- tients were prospectively included (mean age: 51.9±1.7 years).EFth was measured perpendicularly on the free wall of the rightventricle at the end of the systole in 2 echocardiographic views(parasternal short and long axis). Myocardial performance in- dex (MPI) was calculated using tissue Doppler (TD) echocar- diography. Patients were divided into 2 groups according tomedian TD-MPI levels (TD-MPIlow and TD-MPIhigh). Results: EFth values of the TD-MPIhigh group were higherthan those of the TD-MPIlow group (p

Özet

Amaç: Epikardiyal yağ kalınlığının (EYK) sol ventrikül hipert- rofisi ve diyastolik fonksiyon bozukluğu ile ilişkisi bilinmekte- dir. Ancak, epikardiyal yağ dokusunun miyokart performansıüzerine etkisi bilinmemektedir. Bu çalışmada yeni tanı kon- muş hipertansiyonlu hastalarda EYK ile sol ventrikülün hemsistolik hem de diyastolik fonksiyonunu içeren doku Dopplermiyokart performans indeksi (MPI) arasındaki ilişkiyi araştır- mayı amaçladık. Yöntemler: Bu çalışmaya, ileriye dönük olarak (ortalama yaş:51.9±1.7 yıl) olan 314 ardışık yeni tanı konmuş hipertansi- yonlu hasta dahil edildi. EYK iki ekokardiyografik görüntüde(parasternal uzun ve kısa aks) sistol sonunda sağ ventrikülserbest duvarına dik olarak ölçüldü. MPI doku Doppler (tD)ekokardiyografi kullanılarak hesaplandı. Hastalar ortalamatD-MPI değerlerine göre iki gruba ayrıldı (tD-MPIdüşük ve tD- MPIyüksek grup). Bulgular: Doku Doppler MPI yüksek grubun EYK değerle- ri tD-MPIdüşük gruptan yüksek bulundu (p

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Cite This Article

ELBASAN, Z., KALYONCU, A. U., HARBALIOĞLU, H., GÜR, M., ÇAYLI, M., UÇAR, H., ŞEKER, T., BÖREKÇİ, A., BAYKAN, A. O. (2022). Yeni tanı konmuş hipertansiyonlu hastalarda epikardiyal yağ kalınlığının sol ventrikül miyokart performansı ile ilişkisi. Türk Kardiyoloji Derneği Arşivi, Cilt: 43 - Sayı: 8, 705–713. https://ajindex.com/articles/632599

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References (13)

  1. Bays HE. Adiposopathy is “sick fat” a cardiovascular dis- ease? J Am Coll Cardiol 2011;57:2461–73
  2. Bays HE, González-Campoy JM, Bray GA, Kitabchi AE, Bergman DA, Schorr AB, et al. Pathogenic potential of adi- pose tissue and metabolic consequences of adipocyte hyper- trophy and increased visceral adiposity. Expert Rev Cardio- vasc Ther 2008;6:343–68
  3. Tok D, Kadife I, Turak O, Ozcan F, Başar N, Cağlı K, et al. Increased epicardial fat thickness is associated with low grade systemic inflammation in metabolic syndrome. Turk Kardiyol Dern Ars 2012;40:690–5
  4. Mazurek T, Zhang L, Zalewski A, Mannion JD, Diehl JT, Ara- fat H, et al. Human epicardial adipose tissue is a source of inflammatory mediators. Circulation 2003;108:2460–6
  5. Iacobellis G, Leonetti F. Epicardial adipose tissue and in- sulin resistance in obese subjects. J Clin Endocrinol Metab 2005;90:6300–2
  6. Gorter PM, van Lindert AS, de Vos AM, Meijs MF, van der Graaf Y, Doevendans PA, et al. Quantification of epicardial and peri-coronary fat using cardiac computed tomography; reproducibility and relation with obesity and metabolic syn- drome in patients suspected of coronary artery disease. Ath- erosclerosis 2008;197:896–903
  7. Iacobellis G, Gao YJ, Sharma AM. Do cardiac and perivas- cular adipose tissue play a role in atherosclerosis? Curr Diab Rep 2008;8:20–4
  8. Ahn SG, Lim HS, Joe DY, Kang SJ, Choi BJ, Choi SY, et al. Relationship of epicardial adipose tissue by echocardiography to coronary artery disease. Heart 2008;94:7
  9. Teijeira-Fernandez E, Eiras S, Grigorian-Shamagian L, Fer- nandez A, Adrio B, Gonzalez-Juanatey JR. Epicardial adipose tissue expression of adiponectin is lower in patients with hy- pertension. J Hum Hypertens 2008;22:856–63
  10. Iacobellis G, Ribaudo MC, Zappaterreno A, Iannucci CV, Le- onetti F. Relation between epicardial adipose tissue and left ventricular mass. Am J Cardiol 2004;94:1084–7
  11. Turak O, Özcan F, Canpolat U, Işleyen A, Cebeci M, Öksüz F, et al. Increased echocardiographic epicardial fat thickness and high-sensitivity CRP level indicate diastolic dysfunction in patients with newly diagnosed essential hypertension. Blood Press Monit 2013;18:259–64
  12. Kuroda T, Seward JB, Rumberger JA, Yanagi H, Tajik AJ. Left ventricular volume and mass: Comparative study of two-dimensional echocardiography and ultrafast computed tomography. Echocardiography 1994;11:1–9
  13. Tei C, Ling LH, Hodge DO, Bailey KR, Oh JK, Rodeheffer RJ, et al. New index of combi