SavedAdd your journal

Journals / Türk Kardiyoloji Derneği Arşivi / 2016 / Cilt: 44 - Sayı: 4

Arter sertlik parametreleri kalp fonksiyonları normal olan hastalardavitamin D eksikliği ve tedavisi ile ilişkilidir

Arterial stiffness parameters associated with vitamin D deficiency and supplementation in patients with normal cardiac functions

Murat SÜNBÜL
Mehmet BOZBAY
Ekmel Burak ÖZŞENEL
Ceyhun MAMMADOV
Altuğ ÇİNÇİN
İbrahim SARI
Yelda BAŞARAN
Halil ATAŞ
Pages
281–288
Publication Date
2022-11-05
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Arterial stiffness parameters were evaluated using Mobil-O-Graph arteriograph system, which detected signals from the brachial artery before and after treatment.Results: Vitamin D levels significantly increased after treatment (9.0 [6.00] nmol/L vs 29.0 [11.50] nmol/L, p

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objective: Arterial stiffness parameters including pulse wave velocity (PWV) and augmentation index (AIx) are associated with increased risk of cardiovascular disease.
📊
Key Findings & Data:A close relationship has been demonstrated between vitamin D deficiency and cardiovascular disease.
💡
Conclusion & Impact:Arterial stiffness parameters were evaluated using Mobil-O-Graph arteriograph system, which detected signals from the brachial artery before and after treatment.Results: Vitamin D levels significantly increased after treatment (9.0 [6.00] nmol/L vs 29.0 [11.50] nmol/L, p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: Arterial stiffness parameters including pulse wave velocity (PWV) and augmentation index (AIx) are associated with increased risk of cardiovascular disease. A close relationship has been demonstrated between vitamin D deficiency and cardiovascular disease. The aim of the present study was to investigate effects of vitamin D deficiency and supplementation on arterial stiffness parameters in patients with normal cardiac functions.Methods: Study population consisted of 45 patients with vitamin D deficiency and normal cardiac functions. Median age (interquartile range) was 45.0 (12.00) years, and 33 patients were female. Patients were treated with oral administration of vitamin D3. Arterial stiffness parameters were evaluated using Mobil-O-Graph arteriograph system, which detected signals from the brachial artery before and after treatment.Results: Vitamin D levels significantly increased after treatment (9.0 [6.00] nmol/L vs 29.0 [11.50] nmol/L, p

Özet

Amaç: Arter sertlik parametrelerinden nabız dalga hızı (NDH) ve artırma indeksi (AIx) artmış kardiyovasküler risk ile ilişkilidir. Önceki çalışmalarda vitamin D eksikliği ve kardiyovasküler hastalık arasında yakın bir ilişki olduğu gösterilmiştir. Çalışmamızın amacı normal kalp fonksiyonları olan hastalarda vitamin D eksikliğinin ve tedavisinin arter sertlik parametreleri üzerine etkisini araştırmaktır.Yöntemler: Çalışma grubu, vitamin D eksikliği olan, kalp fonksiyonları normal 45 hastadan oluştu. Hastaların ortanca yaşı 45.0 (12.00) yıl idi ve 33'ü kadındı. Hastalar oral vitamin D3 ile tedavi edildi. Arter sertlik parametreleri hastaların tedavi öncesinde ve tedavi sonrasında brakiyal arter akımını saptayan Mobil-O-Graph cihazı kullanılarak değerlendirildi.Bulgular: Vitamin D seviyeleri hastaların tedavisi sonrasında anlamlı olarak arttı (9.0 [6.00] nmol/L, 29.0 [11.50] nmol/L, p

🔖

Cite This Article

SÜNBÜL, M., BOZBAY, M., ÖZŞENEL, E. B., MAMMADOV, C., ÇİNÇİN, A., SARI, İ., BAŞARAN, Y., ATAŞ, H. (2022). Arter sertlik parametreleri kalp fonksiyonları normal olan hastalardavitamin D eksikliği ve tedavisi ile ilişkilidir. Türk Kardiyoloji Derneği Arşivi, Cilt: 44 - Sayı: 4, 281–288. https://ajindex.com/articles/632577

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (10)

  1. Lips P. Worldwide status of vitamin D nutrition. J Steroid Bio- chem Mol Biol 2010;121:297-300.
  2. Bouillon R, Carmeliet G, Verlinden L, van Etten E, Verstuyf A, Luderer HF, et al. Vitamin D and human health: lessons from vitamin D receptor null mice. Endocr Rev 2008;29:726- 76. Holick MF, Matsuoka LY, Wortsman J. Age, vitamin D, and solar ultraviolet. Lancet 1989;2:1104-5.
  3. Wang L, Manson JE, Song Y, Sesso HD. Systematic review: Vitamin D and calcium supplementation in prevention of car- diovascular events. Ann Intern Med 2010;152:315-23.
  4. Burgaz A, Orsini N, Larsson SC, Wolk A. Blood 25-hy- droxyvitamin D concentration and hypertension: a meta-anal- ysis. J Hypertens 2011;29:636-45.
  5. Muscogiuri G, Sorice GP, Ajjan R, Mezza T, Pilz S, Prioletta A, et al. Can vitamin D deficiency cause diabetes and cardio- vascular diseases? Present evidence and future perspectives. Nutr Metab Cardiovasc Dis 2012;22:81-7.
  6. Beveridge LA, Witham MD. Vitamin D and the cardiovascu- lar system. Osteoporos Int 2013;24:2167-80. Vanlint S. Vitamin D and obesity. Nutrients 2013;5:949-56.
  7. Recio-Mayoral A, Banerjee D, Streather C, Kaski JC. En- dothelial dysfunction, inflammation and atherosclerosis in chronic kidney disease--a cross-sectional study of predialysis, dialysis and kidney-transplantation patients. Atherosclerosis 2011;216:446-51.
  8. Sunbul M, Agirbasli M, Durmus E, Kivrak T, Akin H, Aydin Y, et al. Arterial stiffness in patients with non-alcoholic fatty liver disease is related to fibrosis stage and epicardial adipose tissue thickness. Atherosclerosis 2014;237:490-3.
  9. Chitalia N, Recio-Mayoral A, Kaski JC, Banerjee D. Vi- tamin D deficiency and endothelial dysfunction in non- dialysis chronic kidney disease patients. Atherosclerosis 2012;220:265-8.
  10. Giallauria F, Milaneschi Y, Tanaka T, Maggio M, Canepa M, Elango P, et al. Arterial stiffness and vitamin D levels: the Baltimore longitudinal study of aging. J Clin Endocrinol Metab 2012;97:3717-23. 13. Ryu OH, Chung W, Lee S, Hong KS, Choi MG, Yoo HJ. The effect of high-dose vitamin D supplementation on insulin re-sistance and arterial stiffness in patients with type 2 diabetes. Korean J Intern Med 2014;29:620-9. 14. Chitalia N, Ismail T, Tooth L, Boa F, Hampson G, Goldsmith D, et al. Impact of vitamin D supplementation on arterial va-somotion, stiffness and endothelial biomarkers in chronic kid-ney disease patients. PLoS One 2014;9:e91363. 15. Holick MF, Binkley NC, Bischoff-Ferrari HA, Gordon CM, Hanley DA, Heaney RP, et al. Evaluati