Journals / Türk Jinekoloji ve Obstetrik Derneği Dergisi / 2013 / Cilt: 10 - Sayı: 2

Cerebral venosus sınus thrombosıs ın a healthy women takıng oral contraceptıve: a case report and revıew of lıterature

Oral kontraseptif kullanan sa⁄lıklı kadında serebral venöz sinus trombozu: vaka sunumu ve literatürün gözden geçirilmesi

Pages
110–113
Publication Date
2022-11-05
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Herein we present a 33-years old previously healthy women with CVST who taking OC.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Cerebral venous sinus thrombosis (CVST) is rare than arterial thrombosis.
📊
Key Findings & Data:The use of oral contraceptive (OC) increases the risk of cerebral sinus thrombosis.
💡
Conclusion & Impact:Herein we present a 33-years old previously healthy women with CVST who taking OC.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Cerebral venous sinus thrombosis (CVST) is rare than arterial thrombosis. It can affect all age groups but is seen mostly in young women. The diagnosis of CVST is not easy because of variability of clinical symptoms and signs. The patients can present with headache, papilledema, focal deficit, seizures and coma. The most frequent symptom is severe headache. The most common causes of CVST are pregnancy, puerperium, systemic inşammatory diseases, inherited and acquired coagulation disorders, trauma, lumbar puncture, drugs and infection. The use of oral contraceptive (OC) increases the risk of cerebral sinus thrombosis. If there is an additional hereditary prothrombotic factor, the risk of CVST is more. CVST affects superior sagittal sinus and the lateral sinuses more frequently. More than one sinus is affected in one-third of cases. Computed tomografi helps to exclude other intracranial condition but diagnostic value of CT in CVST is limited. Combination of magnetic resonance imaging (MRI) and magnetic resonance venography (MRV) have replaced cerebral angiography Oral kontraseptif kullanan sağlıklı kadında serebral venz sinus trombozu for diagnosis of CVST. The treatment of CVST contain supportive (hydration, antibiotheraphy, anticonvulsant) and anticoagulan treatment. Heparin is effective and safety for the treatment of CVST because of this, it is the first-line treatment. The safety of heparin treatment also has been shown in those patients who had hemorrhagic infarcts. Outcomes of CVST is variable from death to complete improvement, but in general it is favorable. Recurrence of CVT is not common. Herein we present a 33-years old previously healthy women with CVST who taking OC.

Özet

Serebral venöz sinüs tromboz (SVST) arteriyel trombozdan daha nadirdir. Tüm yaş gruplarını etkileyebilir ancak daha çok genç kadınlarda görülür. Klinik semptom ve bulguların çeşitliliği nedeni ile SVST tanısı kolay değildir. Hastalar baş ağrısı, papilödem, fokal defisit, kasılmalar ve koma gibi bulgularla gelebilir. En sık semptom şiddetli baş ağrısıdır. En sık nedenler gebelik, lohusalık, sistemik inşamatuar hastalıklar, kalıtımsal ve edinilmiş pıhtılaşma bozuklukları, travma, lomber ponksiyon, ilaçlar ve enfeksiyondur. Oral kontraseptif (OK) kullanımı serebral sinüs trombozu riskini arttırır. Eğer ek kalıtsal protrombotik faktör var ise, sinüs ven trombozu riski daha fazladır. SVST en çok superior sagittal sinüs ve lateral sinüslerde görülür. Vakaların üçte birinde, birden fazla sinüs etkilenmiştir. Bilgisayarlı tomografinin SVST'daki tanısal değeri sınırlıdır ancak diğer intrakranial durumların dışlanmasında yardımcı olur. Manyetik rezonans görüntüleme (MRG) ve manyetik rezonans venografinin kombinasyonu SVST tanısında serebral anjiografinin yerini almıştır. SVST tedavisi destek tedavisi (hidrasyon, antibioterapi, antikonvulzan) ve antikoagulan tedavilerini içerir. Heparin tedavisi, SVST tedavisi için etkili ve güvenilirdir. Bu nedenle ilk basamak tedavi olarak bildirilmektedir. Heparin tedavisinin hemorajik infarktı olan hastalarda bile güvenli olduğu gösterilmiştir. SVST sonuçları ölümden tamamen iyileşmeye kadar değişkendir, ancak genel olarak olumludur. SVST rekürrensi sık değildir. Biz 33 yaşında daha öncesinde sağlıklı olup, OK kullanan ve SVST gelişen bir bayan hasta sunmak istedik.

🔖

Cite This Article

GÖKSEDEF, B. P., SUMAN, K. K., KOÇ, B. (2022). Cerebral venosus sınus thrombosıs ın a healthy women takıng oral contraceptıve: a case report and revıew of lıterature. Türk Jinekoloji ve Obstetrik Derneği Dergisi, Cilt: 10 - Sayı: 2, 110–113. https://ajindex.com/articles/631524

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (1)

  1. Renowden S. Cerebral venous sinus thrombosis. Eur Radiol 2004; 14: 215- 26. Ehtisham A, Stern BJ. Cerebral venous thrombosis- a review. Neurologist 2006; 12: 32- 8. Bousser MG, Chiras J, Bories J: Cerebral venous thrombus - a review of 38 cases. Stroke 1985; 16: 199- 213. Dzialo AF, Black-Schaffer RM: Cerebral venous thrombosis in young adults: 2 case reports. Arch Phys Med Rehabil 2001; 82: 683- 8. Holger A, Richard J: Cerebral venous sinus thrombosis. Postgraduate Medical Journal 2000; 76: 891- 903. Lanska DJ, Kryscio RJ: Stroke and intracranial venous thrombosis during pregnancy and puerperium. Neurolgy 1998; 51: 1622- 8. Lanska JD, RJ Kryscio. Risk factors for peripartum and postpartum stroke and intracranial venous thrombosis. Stroke 2000; 31(6): 1274- 82. World Health Organization Collaborative Study of Cardiovascular Disease and Steroid Hormone Contraception. Venous thromboembolic disease and combined oral contraceptives: results of international multi centre casecontrol study. Lancet 1995; 346: 157582. Bertina RM, Rosendaal FR. Venous thrombosis-the interaction of genes and the environment. N Engl J Med 1998; 338: 18401. Stam J. Current concepts: Thrombosis of the cerebral veins and sinuses. N Engl J Med 2005; 352: 1791- 8. Zhang Z, Long J, Li W: Cerebral venous thrombosis: a clinical study of 23 cases. Chinese Medical Journal 2000;113 (11): 1043- 45. Buchanan DS, Brazinsky JH. Dural sinus and cerebral venous thrombosis: incidence in young women receiving oral contraceptives. Arch Neurol 1970; 22: 440- 4. Mancia D, Buccino G, Scoditti U, Pini M, Taqliqfem AR. Low-oestrogen oral contraceptives as a major risk factor for cerebral venous and sinus thrombosis: evidence from a clinical series. Ital J Neurol Sci 1999; 20: 231- 5. Martinelli I, Landi G, Merati G, Cella R, Tosetto A, Mannucci PM. Factor V gene mutation is a risk factor for cerebral venous thrombosis. Thromb Haemost 1996; 75: 3934. Martinelli I, Rosendaal FR, Vandenbroucke JP, Mannucci PM. Oral contraceptives are a risk factor for cerebral vein thrombosis [letter]. Thromb Haemost 1996; 76: 4778. Vandenbroucke JP, Rosing J, Bloemenkamp KW, Middeldorp S, Helmerhorst FM, Bouma BN, et al. Oral contraceptives and the risk of venous thrombosis. The N Engl J Med 2001; 344: 1527- 35. De Brujin SF, Stam J, Koopman MM, Vendenbroucke JP. Case-control study of risk of cerebral sinus thrombosis in oral contraceptive users who are carriers of hereditary prothrombotic conditions. BMJ 1998; 316: 589- 92. M