Journals / Türk Jinekoloji ve Obstetrik Derneği Dergisi / 2011 / Cilt: 8 - Sayı: 2

Retropective analysis of 25 cases with borderline ovarian tumors

Borderline over tümörlü 25 olgunun retrospektif analizi

Pages
107–112
Publication Date
2022-11-04
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Cystectomy might be chosen in young patients with fertilty desire, however, patients should be warned for high recurrence rates.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: To determine the borderline ovarian tumors according to clinical features, treatment methods, recurrence and survival rates.
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Key Findings & Data:Data were analyzed with SPSS 13.0.
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Conclusion & Impact:Cystectomy might be chosen in young patients with fertilty desire, however, patients should be warned for high recurrence rates.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: To determine the borderline ovarian tumors according to clinical features, treatment methods, recurrence and survival rates. Material and methods: Twenty-five cases were included to this study. Demographic and clinical findings, surgical methods, stage of disease, recurrences and survivals were revealed from hospital records. Data were analyzed with SPSS 13.0. Results: Mean age were 42.7±17.9. Most of the patients were in premenopausal (n=19, 76%). Mean tumor size were 13.44±9.37 cm (range 4-30 cm) and 16 of the patients had serous and 9 of them had musinous histologic type. Mean tumor size of serous and mucinous tumors were 9.44±6.78 cm, 20.56±9.4 cm, respectively and the difference was statisticallly significant (p=0.007). Tumor markers were elevated in 17 of the patients (68%) before the surgery. Twenty-two patients had frozen section (88%), accuracy rate of the frozen section was 90%. during surgery. Most of the patients were treated with total abdominal hysterectomy bilateral salpingo-oophorectomy (TAH-BSO) (n=12), 6 of the patients were treated with cystectomy and the others were treated with unilateral oophorectomy (USO) (n=7). Most of the cases were stage I (n=23, 92%). Recurrence of the disease was detected in 4 patients (16%) and 2 of them were treated with cystectomy and the others were treated with USO. No recurrence was detected in TAH-BSO group. Conclusions: Borderline tumors have perfect prognosis and most of the cases are premenopausal. The suggested treatment is surgical staging with TAH-BSO. Cystectomy might be chosen in young patients with fertilty desire, however, patients should be warned for high recurrence rates.

Özet

Amaç: Borderline over tümörlü vakaların klinik özellikleri ile birlikte uygulanan tedavi yöntemleri, rekürrens ve sağkalım oranlarının ortaya konulmasıdır. Gereç ve yöntemler: Bu çalışmaya 25 borderline over tümörü olgusu dahil edildi. Retrospektif olarak olguların dosya kayıtlarından demografik ve klinik bulguları, yapılan cerrahinin türü, hastalığın evresi, rekürrens durumu ve sağkalım sürelerine ulaşıldı. Bulgular SPSS 13.0 ile analiz edildi. Bulgular: Ortalama yaş 42,7±17,9 idi. Hastaların çoğunluğu premenopozal (n=19, %76) idi. Ortalama tümör çapı 13,44±9,37 cm (4-30 cm aralığında), histolojik açıdan %64 (16/25) seröz, %36 (9/25) müsinöz olarak belirlendi. Seröz tümörlerde ortalama tümör çapı 9,44±6,78 cm iken, müsinözlerde 20,56±9,4 cm ve iki grup arasında istatiksel olarak anlamlı fark saptandı (p= 0,007). Cerrahi öncesinde tümör belirteçleri 17 hastada yüksek saptandı (%68). Yirmiiki hastada frozen kesit uygulandı (%88), frozen doğruluk oranı %90 olarak belirlendi. Olguların 12’si total abdominal histerektomi bilateral salpingoooferektomi (TAH-BSO), 6 olgu kistektomi, 7 olgu unilateral salpingoooferektomi (USO) ile tedavi edildi. Olguların çoğunluğu evre 1 (n=23, %92) idi. Rekürrens 4 olguda saptandı (16%) ve 2’si sadece kistektomi ile diğer 2’si ise unilateral ooferektomi ile tedavi edilen olgulardı. TAH-BSO ile tedavi edilen olgularda rekürrens görülmedi. Sonuç: Borderline tümörler sıklıkla premenopozal dönemde görülen, çok iyi prognoza sahip lezyonlardır. Önerilen tedavi TAH-BSO, cerrahi evrelemedir. Kistektomi, fertilite isteği olan genç olgularda seçilebilir ancak hasta yüksek rekürrens oranları açısından uyarılmalıdır.

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Cite This Article

GÖKSEDEF, Ç. B. P., BARAN, Ş. Y., GÖRGEN, H., ÇETİN, A. (2022). Retropective analysis of 25 cases with borderline ovarian tumors. Türk Jinekoloji ve Obstetrik Derneği Dergisi, Cilt: 8 - Sayı: 2, 107–112. https://ajindex.com/articles/631596

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