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Journals / Türk Kardiyoloji Derneği Arşivi / 2019 / Cilt: 47 - Sayı: 1

Is the use of low molecular weight heparin a rational choice during pregnancy in patients with a mechanical heart valve: a report of three cases

Mekanik kalp kapaklı hastalarda gebelik sırasında düşük molekül ağırlıklı heparin kullanımı akılcı seçim mi?: Üç olgu sunumu

Sabahattin Gündüz
Emrah Bayam
Mehmet Özkan
Ahmet Güner
Semih Kalkan
Pages
63–68
Publication Date
2022-11-05
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Presentlydescribed are 3 cases of therapy with LMWH during pregnancy.Despite frequent anti-factor Xa monitoring, not surprisingly,all of them developed prosthetic valve thrombosis.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Pregnancy is associated with an increased riskof valve thrombosis in patients with a mechanical prostheticheart valve.
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Key Findings & Data:The administration of low molecular weight heparin(LMWH) with regular anti-factor Xa assessment is a recommendedtreatment modality for these patients.
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Conclusion & Impact:Presentlydescribed are 3 cases of therapy with LMWH during pregnancy.Despite frequent anti-factor Xa monitoring, not surprisingly,all of them developed prosthetic valve thrombosis.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Pregnancy is associated with an increased riskof valve thrombosis in patients with a mechanical prostheticheart valve. The administration of low molecular weight heparin(LMWH) with regular anti-factor Xa assessment is a recommendedtreatment modality for these patients. Presentlydescribed are 3 cases of therapy with LMWH during pregnancy.Despite frequent anti-factor Xa monitoring, not surprisingly,all of them developed prosthetic valve thrombosis.

Özet

Gebelik, mekanik protez kalp kapak trombozu riski ile ilişkilidir. Düşük molekül ağırlıklı heparin (LMWH) kullanan hastalar için düzenli anti-faktör Xa değerlendirmesi önerilmektedir. Burada, gebelik sırasında LMWH ile tedavide üç olgu sunmaktayız. Düzenli anti-faktör Xa monitörizasyonu altında şaşırtıcı olmayan bir şekilde hepsinde protez kapak trombozu gelişti.

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Cite This Article

Gündüz, S., Bayam, E., Özkan, M., Güner, A., Kalkan, S. (2022). Is the use of low molecular weight heparin a rational choice during pregnancy in patients with a mechanical heart valve: a report of three cases. Türk Kardiyoloji Derneği Arşivi, Cilt: 47 - Sayı: 1, 63–68. https://ajindex.com/articles/625972

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