SavedAdd your journal

Journals / Türk Biyokimya Dergisi / 2015 / Cilt: 40 - Sayı: 5

İkili Tarama Testi medyan değerleri bölgesel midir?

Is median value of Double Screening Test regional?

Ramazan KOCABAŞ
Abdulkerim BEDİR
Tülay ÖZDEMİR
Hacı Kemal ERDEMLİ
Pages
431–437
Publication Date
2022-11-05
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Results were given as median (minimum-maximum) values.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objective: The median values of double test which is commonly used for Down Syndrome screening show diversity between countries.
📊
Key Findings & Data:In this study, we aimed to investigate the possible differences in corrected multiplies of median (MoM) values of individiuals between the two cities of the same geographic region.Methods: Blood samples for double test analysis, sent from Çorum and Samsun, were studied in the same laboratory.
💡
Conclusion & Impact:Results were given as median (minimum-maximum) values.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: The median values of double test which is commonly used for Down Syndrome screening show diversity between countries. In this study, we aimed to investigate the possible differences in corrected multiplies of median (MoM) values of individiuals between the two cities of the same geographic region.Methods: Blood samples for double test analysis, sent from Çorum and Samsun, were studied in the same laboratory. Results of double test analyses were retrospectively evaluated. Mann-Whitney U test was used for comparison of corrected MoM values of free human chorionic gonadotropin (f-? hCG) and pregnancy-specific plasma protein-A (PAPP-A) according to gestational age. Results were given as median (minimum-maximum) values. The p

Özet

Amaç: Down Sendromu taramasında sıklıkla kullanılan ikili test medyan değerleri ülkeler arasında farklılık göstermektedir. Bu çalışmamızda aynı coğrafi bölgede bulunan iki ildeki bireylerin düzeltilmiş multiplies of median (MoM) değerleri arasında farklılık olup olmadığının araştırılması amaçlandı.Metod: Çorum ve Samsun illerinden aynı laboratuvara numune gönderilerek çalışılan ikili test sonuçları retrospektif olarak değerlendirildi. Serbest beta insan koryonik gonadotropin (s-? hCG) ve gebeliğe özgü plazma protein-A (PAPP-A) testleri için gebelik haftalarına göre elde edilen düzeltilmiş MoM değerleri Mann-Whitney-U testi ile değerlendirildi. Sonuçlar medyan (minimum-maksimum) olarak verildi. p

🔖

Cite This Article

KOCABAŞ, R., BEDİR, A., ÖZDEMİR, T., ERDEMLİ, H. K. (2022). İkili Tarama Testi medyan değerleri bölgesel midir?. Türk Biyokimya Dergisi, Cilt: 40 - Sayı: 5, 431–437. https://ajindex.com/articles/621107

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (11)

  1. Çınar Kuşkucu A. Fetal Kromozom Anomalisi Tarama Testleri. JOPP Derg 2010; 2(2):55-60.
  2. Guedj F, Bianchi DW. Noninvasive prenatal testing creates an opportunity for antenatal treatment of Down syndrome. Prenat Diagn 2013; 33(6):614-8.
  3. Lamson sH, Hook EB. A simple function for maternal-age- specific rates of Down syndrome in the 20-to-49-year age range and its biological implications. Am J Hum Genet 1980; 32(5):743-53.
  4. Fuchs KM, Peipert JF. First trimester Down syndrome screening: public health implications. semin Perinatol 2005; 29(4):267-71.
  5. Özalp Yüreğir Ö, Büyükkurt s, Koç F, Pazarbaşı A. Prenatal (Doğum Öncesi) Tanı Arşiv Kaynak Tarama Dergisi (Archives Medical Review Journal) 2012; 21(1):80-94. spencer K, Macri JN, Aitken DA, Connor JM. Free beta-hCG as first-trimester marker for fetal trisomy. Lancet 1992; 339(8807):1480. Wald N, stone R, Cuckle Hs, Grudzinskas JG, Barkai G, et al. First trimester concentrations of pregnancy associated plasma protein A and placental protein 14 in Down's syndrome. BMJ 1992; 305(6844):28. Kafkaslı A. Gebelikte Down sendromu Tanısı için Tarama Testleri ve Güvenilirlikleri. TJD Uzmanlık sonrası Eğitim Dergisi 2004; 6:30-5.
  6. Peuhkurinen s, Laitinen P, Honkasalo T, Ryynanen M, Marttala J. Comparison of combined, biochemical and nuchal translucency screening for Down syndrome in first trimester in Northern Finland. Acta Obstet Gynecol scand 2013; 92(7):769-74.
  7. Yu DY, Wang F, Liu Q, Jiang N, Zhao W, et al. Establishment and application of median serum markers for second trimester screening in Qingdao region. [Article in Chinese] Zhonghua Yi Xue Yi Chuan Xue Za Zhi 2012; 29(5):587-91. [Abstract] Cavalli P. False-negative results in Down's syndrome screening. Lancet 1996; 347(9006):965-6.
  8. Atak PG, Arpacı A, seydal G. Determination of the median levels of double and triple prenatal screening parameters in Adıyaman region. Türk Biyokimya Dergisi [Turkish Journal of Biochemistry-Turk J Biochem] 2014; 39(2);231-7.
  9. Wald NJ, Hackshaw AK. Combining ultrasound and biochemistry in first-trimester screening for Down's syndrome. Prenat Diagn 1997; 17(9):821-9.
  10. Malone FD, Canick JA, Ball RH, Nyberg DA, Comstock CH, et al. First-trimester or second-trimester screening, or both, for Down's syndrome. N Engl J Med 2005; 353(19):2001-11. spencer K, Aitken D. Factors affecting women's preference for type of prenatal screening test for chromosomal anomalies. Ultrasound Obstet Gynecol 2004; 24(7):735-9.
  11. Öztürk Ö, Karaşahin E, Alanbay İ, serdar M, Ö