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Journals / Türk Biyokimya Dergisi / 2018 / Cilt: 43 - Sayı: 1

Evaluation of serum 25-hidroxy vitamin D and zinc levels in asthmatic patients

Astımlı hastalarda serum 25 hidroksi vitamin D ve çinko düzeylerinin değerlendirilmesi

Murat ELEVLİ
Hatice Nilgün DURU
Mahmut ÇİVİLİBAL
Ayşe Ergül BOZACI
Barış Belgin AKTAŞ
Kamil ŞAHİN
Pages
49–56
Publication Date
2022-11-05
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

As the level of vitamin D increased, a decrease inseverity of asthma was seen (p = 0.04).Conclusion: Though larger series are needed to arrive atdefinitive conclusions, we think that vitamin D deficiencyrather than zinc deficiency, might convey importance inthe emergence, and exacerbation of asthma.

📌 3 Key Takeaways

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Objective & Hypothesis:Introduction: We aimed to investigate the impact of serumzinc, and vitamin D levels on the development of asthma,and its clinical characteristics.Methods: In our cross-sectional study; 50 patients whowere diagnosed as atopic asthma and 70 healthy childrenconsisted the control group.
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Key Findings & Data:In both groups levels ofvitamin D, and zinc were analyzed.Results: A statistically significant intergroup differencewas not detected as for age, gender, body height (percentile),and weight (percentile) of the patients (p > 0.05).Mean vitamin D levels in the asthmatic patient, and controlgroups were 32.61 ± 9.48 nmol/L, and 42.55 ± 15.42 nmol/L,respectively.
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Conclusion & Impact:As the level of vitamin D increased, a decrease inseverity of asthma was seen (p = 0.04).Conclusion: Though larger series are needed to arrive atdefinitive conclusions, we think that vitamin D deficiencyrather than zinc deficiency, might convey importance inthe emergence, and exacerbation of asthma.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Introduction: We aimed to investigate the impact of serumzinc, and vitamin D levels on the development of asthma,and its clinical characteristics.Methods: In our cross-sectional study; 50 patients whowere diagnosed as atopic asthma and 70 healthy childrenconsisted the control group. In both groups levels ofvitamin D, and zinc were analyzed.Results: A statistically significant intergroup differencewas not detected as for age, gender, body height (percentile),and weight (percentile) of the patients (p > 0.05).Mean vitamin D levels in the asthmatic patient, and controlgroups were 32.61 ± 9.48 nmol/L, and 42.55 ± 15.42 nmol/L,respectively. Between two groups a statistically significantdifference was found (p = 0.001). Zinc levels were higherin the control group without any statistically significantdifference between groups (p = 0.25). A statistically significantnegative correlation (−0.635) was found betweenvitamin D levels, and severity of asthma in the patientgroup. As the level of vitamin D increased, a decrease inseverity of asthma was seen (p = 0.04).Conclusion: Though larger series are needed to arrive atdefinitive conclusions, we think that vitamin D deficiencyrather than zinc deficiency, might convey importance inthe emergence, and exacerbation of asthma.

Özet

Giriş: Biz, serum çinko ve vitamin D düzeylerinin astım gelişimi ve klinik özellikleri üzerine olan etkisinin araştırılmasını amaçladık. Yöntemler: Kesitsel çalışmamız, atopik astım tanısı konulan 50 hasta ve kontrol grubunu oluşturan 70 hastadan oluşmaktaydı. Her iki grubun D vitamini ve çinko düzeyleri analiz edildi. Bulgular: Gruplar arasında yaş, cinsiyet, boy (percentil) ve kilo (percentil) açısından yapılan karşılaştırmada istatistiksel anlamlı farklılık tespit edilmedi (p > 0,05). Gruplar arasında D vitamini ortalamaları astımlı hastalarda ve kontrol grubunda sırasıyla 32,61 ± 9,48 nmol/L ve 42,55 ± 15,42 nmol/L bulundu. İki grup arasında, istatistiksel anlamlı farklılık bulundu (p = 0,001). Çinko düzeyleri, iki grup arasında istatistiksel anlamlı fark olmadan, kontrol grubunda daha yüksekti (p = 0,25). Hasta grubunda D-Vitamini ile astım şiddeti arasında, istatistiksel olarak anlamlı negatif bir korelasyon (−0,635) bulundu. Sonuç: Daha geniş serilere ihtiyaç olmakla birlikte, astımın ortaya çıkması ve şiddetlenmesinde D vitamini düşüklüğünün önemli olabileceğini, çinkonun ise etkisi olmadığını düşünmekteyiz.

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Cite This Article

ELEVLİ, M., DURU, H. N., ÇİVİLİBAL, M., BOZACI, A. E., AKTAŞ, B. B., ŞAHİN, K. (2022). Evaluation of serum 25-hidroxy vitamin D and zinc levels in asthmatic patients. Türk Biyokimya Dergisi, Cilt: 43 - Sayı: 1, 49–56. https://ajindex.com/articles/620973

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