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Journals / Türk Biyokimya Dergisi / 2021 / Cilt: 46 - Sayı: 2

A notable key for estimating the severity of COVID-19: 25-hydroxyvitamin D status

COVID-19’un şiddetini tahmin etmek için dikkate değer bir anahtar: 25-hidroksivitamin D durumu

Seval İZDEŞ
Özcan EREL
İhsan ATEŞ
İbrahim MUNGAN
Salim NEŞELİOĞLU
Merve ERGİN TUNCAY
Zübeyr Said AĞAÇ
Emin GEMCİOĞLU
Şerif GÖKBULUT BEKTAŞ
Ahmet Gökhan AKDAĞ
Bircan KAYAASLAN
İmran HASANOĞLU
Ayşe KAYA KALEM
Rahmet GÜNER
Fatma ESER
Adalet AYPAK
Pages
167–172
Publication Date
2022-11-06
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Results: In all COVID-19 groups 25(OH)D levels were low compared to controls (p

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Background: Vitamin D is recognized to be an immune regulator.
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Key Findings & Data:Objectives: To examine the 25-hydroxyvitamin D (25(OH) D) status for assessing the severity of COVID-19.
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Conclusion & Impact:Results: In all COVID-19 groups 25(OH)D levels were low compared to controls (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Background: Vitamin D is recognized to be an immune regulator. Also, it is known to have antiviral effects by several mechanisms, including reducing inflammatory cytokines. Objectives: To examine the 25-hydroxyvitamin D (25(OH) D) status for assessing the severity of COVID-19. Methods: This study consisted of 596 patients confirmed as SARS-CoV-2 infection and 59 healthy individuals. The cases separated into non-severe group, severe survival, and severe non-survival group. 25(OH)D and other labo ratory parameters were evaluated retrospectively. Results: In all COVID-19 groups 25(OH)D levels were low compared to controls (p

Özet

Amaç: D vitamini bir bağışıklık düzenleyici olarak kabul edilir ve ayrıca inflamatuar sitokinlerin azaltılması da dahil olmak üzere çeşitli mekanizmalarla antiviral etkilere sahip olduğu bilinmektedir. Çalışmanın amacı COVID-19’un şiddetini değerlendirmek için 25-hidroksivitamin D (25 (OH) D) durumunu incelemekti. Gereç ve yöntem: Bu çalışma, SARS-CoV-2 enfeksiyonu olarak doğrulanan 596 hasta ve 59 sağlıklı kişiden oluştu. Vakalar şiddetli olmayan grup, şiddetli sağ kalan ve şiddetli sağ olmayan grup olarak ayrıldı. 25 (OH) D ve diğer labo ratuvar parametreleri geriye dönük olarak değerlendirildi. Bulgular: Tüm COVID-19 gruplarında 25 (OH) D seviyeleri kontrollere kıyasla düşüktü (p

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Cite This Article

İZDEŞ, S., EREL, Ö., ATEŞ, İ., MUNGAN, İ., NEŞELİOĞLU, S., TUNCAY, M. E., AĞAÇ, Z. S., GEMCİOĞLU, E., BEKTAŞ, Ş. G., AKDAĞ, A. G., KAYAASLAN, B., HASANOĞLU, İ., KALEM, A. K., GÜNER, R., ESER, F., AYPAK, A. (2022). A notable key for estimating the severity of COVID-19: 25-hydroxyvitamin D status. Türk Biyokimya Dergisi, Cilt: 46 - Sayı: 2, 167–172. https://ajindex.com/articles/620692

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