Journals / Türk Anestezi ve Reanimasyon Dergisi / 2003 / Cilt: 31 - Sayı: 6

The immune responses in anesthesiologists

Anesteziyologlarda immün yanıtlar

Pages
279–283
Publication Date
2022-11-05
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

It was found that only serum IgM concentration was statistically significant high in 3rd-5th year anesthesia resident group among anesthesiologist groups.

📌 3 Key Takeaways

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Objective & Hypothesis:There are contradictory reports about immunological responses in anesthetic personnel chronically exposure inhalational anesthetic agents.
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Key Findings & Data:So we aimed to determine immune responses in 30 anesthesiologists and 30 healthy control subjects.
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Conclusion & Impact:It was found that only serum IgM concentration was statistically significant high in 3rd-5th year anesthesia resident group among anesthesiologist groups.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

There are contradictory reports about immunological responses in anesthetic personnel chronically exposure inhalational anesthetic agents. So we aimed to determine immune responses in 30 anesthesiologists and 30 healthy control subjects. Anesthesiologists were subdivided into three groups according to the anaesthetists-practicing-period as short (less than 3 years), moderate (for 3 to 5 years) and long period practisers (for more than 5 years). Hemoglobin concentration, red blood cell count, white blood cell count, plathelet count, neutrophil count, lymphocyte count, percentage of lymphocyte subpopülations (CD3, CD4, CD8, CD16, CD19), serum Immunoglobulin (Ig) A, E, G, M concentrations, purified protein derivative of tuberculin (PPD) test and plasma cortisol level were studied in 30 physician anesthesiologists and 30 healthy control subjects. It was found that only serum IgM concentration was statistically significant high in 3rd-5th year anesthesia resident group among anesthesiologist groups. But there was no statistically significant difference in comparing with control group. We concluded that immune responses in anesthesiologists were not different from control group.

Özet

İnhalasyonel anestezik ajanlara kronik olarak maruz kalan anestezi personelinde immünolojik yanıtlar hakkında çelişkili raporlar vardır. Bu nedenle biz 30 anestezi doktorunda ve kontrol grubu olarak 30 sağlıklı erişkinde immün yanıtları değerlendirmeyi amaçladık. Anesteziyologlar, 0-2.yıl anestezi asistanı (n=7), 3.-5. yıl anestezi asistanı (n=13) ve 6-14 yıllık anesteziyolog (n=10) olmak üzere üç gruba ayrıldı. Tüm olgularda; hemoglobin konsantrasyonu, kırmızı ve beyaz küre sayımı, trombosit, nötrofil ve lenfosit sayımı, lenfosit subpopülasyonlarının (CD3, CD4, CD8, CD16, CD19) yüzdesi, serum immünoglobulin (İg) A, E, G, M konsantrasyonları, tüberkülinin saflaştırılmış protein derivesi (PPD) testi ve plazma kortizol düzeyi çalışıldı. Gruplar arasında, 3.-5. yıl anestezi asistanı grubunda serum İgM konsantrasyonu diğer gruplara göre istatistiksel olarak anlamlı şekilde yüksekti. Ancak kontrol grubu ile karşılaştırıldığında istatistiksel olarak anlamlı bir farklılık yoktu. Sonuç olarak anesteziyologlarda immün yanıtları ve plazma kortizol düzeyini kontrol grubundan farksız bulduk.

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Cite This Article

TOSUN, Z., PATIROĞLU, T., MADENOĞLU, H., BOYACI, A. (2022). The immune responses in anesthesiologists. Türk Anestezi ve Reanimasyon Dergisi, Cilt: 31 - Sayı: 6, 279–283. https://ajindex.com/articles/620255

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