Journals / Türk Anestezi ve Reanimasyon Dergisi / 2003 / Cilt: 31 - Sayı: 5

The effects of sevoflurane and propofol on induction, maintenance and recovery in elderly patients

Yaşlı olgularda sevofluran ve propofolün indüksiyon, idame ve derlenmeye etkisi

Pages
224–230
Publication Date
2022-11-05
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

The only difference is that induction time was shorter significantly in the group P (p

📌 3 Key Takeaways

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Objective & Hypothesis:In this study, we aimed to compare the effects of sevoflurane and propofol on induction, maintenance and recovery in elderly patients.
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Key Findings & Data:Forty patients, ASA class I-II, more than 60 years of age, undergoing elective surgery that last between 2-4 hours were taken into the study.
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Conclusion & Impact:The only difference is that induction time was shorter significantly in the group P (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

In this study, we aimed to compare the effects of sevoflurane and propofol on induction, maintenance and recovery in elderly patients. Forty patients, ASA class I-II, more than 60 years of age, undergoing elective surgery that last between 2-4 hours were taken into the study. Anaesthesia was induced with 66 % N2O and 7 % sevoflurane in the group S (n=20) and 1-2 mg kg-1 propofol approximately within 30 seconds in the group P (n=20). In the two groups; loss of consciousness, loss of eyelid reflex, time to intubation, adverse effects during induction, heart rate (HR) and mean arterial pressure (MAP) after first, third and fifth minutes of induction were recorded. Maintenance of anaesthesia was provided with 66 % N2O and 1-4 % sevoflurane in group S, 2-10 mg kg -1 h-1 propofol and 66 % N2O in group P. HR and MAP values were determined after first minutes of intubation until the end of the operation. At the end of operation after discontinuation of anaesthetic agents, times to extubation, eye opening, verbal response, orientation and Aldrete score >8 were recorded. The only difference is that induction time was shorter significantly in the group P (p

Özet

Bu çalışmada 60 yaş üzerindeki olgularda sevofluran ve propofolün indüksiyon, idame ve derlenme üzerine etkilerini karşılaştırmayı amaçladık. ASA I-II sınıfı, 60 yaş üzerinde, elektif cerrahi uygulanacak ve ameliyatı 2-4 saat sürmesi beklenen 40 olgu çalışmaya alındı. Sevofluran grubunda (Grup S, n=20); anestezi indüksiyonu % 66 N2O içinde % 7 sevofluran ile sağlanırken, propofol grubunda (Grup P, n=20) İV 1-2 mg kg-1 propofol ile yaklaşık 30 sn de gerçekleştirildi. Her iki grupta da; bilinç kaybı, kirpik refleksi kaybı ve entübasyon süreleri, indüksiyon sırasında karşılaşılan yan etkiler ve indüksiyondan sonraki bir, üç ve beşinci dakikalardaki kalp atım hızı (KAH) ve ortalama arter basıncı (OAB) değerleri kaydedildi. Anestezi idamesi Grup S'de % 1-4 sevofluran ve % 66 N2O, Grup P'de ise 2-10 mg kg-1 st-1 propofol ve % 66 N2O ile sağlandı. Entübasyon sonrası birinci dakikadan itibaren ameliyat bitimine kadar her 30 dk'da bir NS ve OAB değerleri kaydeldi. Cerrahi bitiminde, anestezik ajanlar kesildikten sonra ekstübasyon, göz açma, sözlü uyaranlara yanıt, oryantasyon ve Aldrete skoru>8 olma süreleri saptandı. Grupların; indüksiyon süreleri, indüksiyon ve intraoperatif dönemdeki OAB değerleri propofol grubunda daha düşük bulundu (p

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Cite This Article

BUT, A. K., TOĞAL, T., YÜCEL, A., ERSOY, M. Ö., DURMUŞ, M., GEDİK, E. (2022). The effects of sevoflurane and propofol on induction, maintenance and recovery in elderly patients. Türk Anestezi ve Reanimasyon Dergisi, Cilt: 31 - Sayı: 5, 224–230. https://ajindex.com/articles/620218

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References (17)

  1. Philip BK: What are the best agents for ambulatory general anesthesia, and are they cost effective. Anesth Clin North Am 1996; 14:695-706
  2. Walpole R, Logan M: Effect of sevoflurane concentration on inhalation induction of anaesthesia in the elderly. Br J Anaesth 1999; 82:20-4
  3. Hobbhahn J, Funk W: Sevoflurane in paediatric anesthesia. Anaesthesist 1996; 45:22-7
  4. Hall JE, Stewart JIM, Harmer M: Single-breath inhalation induction of sevoflurane anaesthesia with and without nitrous oxide: a feasibility study in adults and comparison with an intravenous bolus of propofol. Anaesthesia 1997; 52:410-15
  5. Schrum SF, Hannallah RS,.Verghese PM, et al: Comparison of propofol and tiopental for rapid anesthesia induction in infants. Anesth Analg 1994; 78:482-5
  6. Kırkpatrick T, Cockshott ID, Douglas EJ, Nimmo WS: Pharmacokinetics of propofol in elderly patients. Br J Anaesth 1988; 60:146-50
  7. Aldrete JA, Krulik D: A postanesthetic recovery score. Anesth Analg 1970; 49:924-34
  8. Sielenkamper AW, Bnoke M: Anaesthesia and the elderly. Curr Opin Anaesthesiol 2001; 14:679-84
  9. Sloan MH, Conard PF, Karsunky PK, Gross JB: Sevoflurane versus isoflunine: Induction and recovery characteristics with single-breath inhaled induction of anesthesia. Anesth Anals 1996; 82:528-32
  10. Muzi M, Colinco MD, Robinson BJ, Ebert TJ: The effects of premadication on inhaled induction of anesthesia with sevoflurane. Anesth Analg 1997; 85:1143-8
  11. Thwaites A, Edmends S, Smith I: Inhalation induction with sevoflurane: a double-blind comparison with propofol. Br J Anaesth 1997; 78:356-61
  12. Peacock.IE, Lewis RP, Reilly CS, Nimmo S: Effect of different rates of infusion of propofol for induction of anaesthesia in elderly patients. Br J Anaesth 1990; 65:346-52
  13. Dundee JW, Robinson FP, McCollum JSC, Patterson CC: Sensivity to propofol in the elderly. Anaesthesia 1986; 41:482-85
  14. Sukhani R, Vazquez J, Pappas AL: Recovery after propofol with and wilhout uitraoperative fentanyl İn patients undergoing ambulatory gynaecologic laparoscopy. Anesth Analg 1996; 83:975-81
  15. Marshall CA, Jones RM, Bajorck PK, Cashmun JN:Recovery characleristic using isoflurane or propofol for maintenance of anaesthesia: a double-blind controlled trial. Anaesthesia 1992:47:461-6
  16. Jellish WS, Lien CA, Fontenot H.I, Hall R: The comparative effects of sevoflurane versus propofol in the induction and maintenance of anesthesia in adult patients. Anesth Analg 1996; 82:479-85
  17. Pregler J, Ste