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Journals / Türk Anestezi ve Reanimasyon Dergisi / 2003 / Cilt: 31 - Sayı: 6

Comparison of the analgesic effect of morphine, tramadol, bupivacaine and various combination of these drugs in patient-controlled epidural analgesia

Morfin, tramadol, bupivakain ve kombinasyonlarının postoperatif analjezik etkinliklerinin epidural hasta kontrollü analjezi yöntemiyle karşılaştırılması

Nurcan DORUK
Şebnem ATICI
Handan ÇAMDEVİREN
Anış ARIBOĞAN
Pages
284–289
Publication Date
2022-11-05
DOI
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⚡ TL;DR(Too Long; Didn't Read)

Systolic and diastolic blood pressures were significantly lower during the first hour of bupivacain administration in groups III, IV and V compared to morphine and tramadol groups (p

📌 3 Key Takeaways

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Objective & Hypothesis:This study the analgesic effects of morphine, tramadol, bupivacain and various combination of these drugs were investigated using patient-controlled epidural analgesia technique for postoperative pain management after open urologic surgery.
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Key Findings & Data:Sixty-five patients (ASA I-II) included in the study and they were randomly divided in to 5 groups.
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Conclusion & Impact:Systolic and diastolic blood pressures were significantly lower during the first hour of bupivacain administration in groups III, IV and V compared to morphine and tramadol groups (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

This study the analgesic effects of morphine, tramadol, bupivacain and various combination of these drugs were investigated using patient-controlled epidural analgesia technique for postoperative pain management after open urologic surgery. Sixty-five patients (ASA I-II) included in the study and they were randomly divided in to 5 groups. Each group consisted 13 patients and morphine was used in group I, tramadol in group II, bupivakain in group III, bupivacain+tramadol in group IV and bupivacain+morphine in group V. Hearth rate, systolic and diastolic blood pressures, respiratory rate, SpO2, pain score (VAS) and sedation score were assesed at postoperative 5, 15 ,30 minutes and 1, 2, 4, 8, 12, 24 hours. There wasn't any significant difference between the groups by means of SpO2, heart and respiration rates (p>0.05). Systolic and diastolic blood pressures were significantly lower during the first hour of bupivacain administration in groups III, IV and V compared to morphine and tramadol groups (p

Özet

Çalışmamızda ürolojik açık cerrahi hastalarının postoperatif ağrı tedavisinde "Epidural Hasta Kontrollü Analjezi (EHKA)" yöntemi ile morfin, tramadol, bupivakain ve kombinasyonlarının etkilerini karşılaştırmalı olarak değerlendirilmesi planlanlandı. Çalışmaya 65 erişkin hasta (ASA I-II) dahil edildi. Rasgele 13'er kişilik 5 gruba ayrılan hastaların postoperatif ağrı tedavisinde morfin (I. grup), tramadol (II. grup), bupivakain (III. grup), bupivakain+tramadol (IV. grup), bupivakain+morfin (V. grup) kombinasyonları hazırlanan protokole göre EHKA yöntemi kullanılarak uygulandı. Tüm gruplarda; kalp atım hızı, noninvaziv kan basıncı, solunum sayısı, periferik oksijen satürasyonu, ağrı (VAS skoru) ve sedasyon skorları ekstübasyonu takiben 5, 15, 30. dk'larda ve 1, 2, 4, 8, 12, 24. st'lerde değerlendirildi. Gruplar arasında kalp atım hızı, solunum sayısı ve periferik oksijen saturasyonu açısından fark saptanmadı (p>0.05). Kan basıncı, ilk 1 saatlik takiplerde bupivakain ve kombinasyonlarının olduğu gruplarda, morfin ve tramadol gruplarına göre düşük bulundu (p

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Cite This Article

DORUK, N., ATICI, Ş., ÇAMDEVİREN, H., ARIBOĞAN, A. (2022). Comparison of the analgesic effect of morphine, tramadol, bupivacaine and various combination of these drugs in patient-controlled epidural analgesia. Türk Anestezi ve Reanimasyon Dergisi, Cilt: 31 - Sayı: 6, 284–289. https://ajindex.com/articles/620216

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