Journals / Türk Anestezi ve Reanimasyon Dergisi / 2004 / Cilt: 32 - Sayı: 2

Comparison of the fresh gas flows adjusted to the body weights in patients undergoing low flow anaesthesia either with isoflurane or desflurane

Düşük akımlı anestezide izofluran ve desfluran ile vücut ağırlığına göre uygulanan taze gaz akımlarının karşılaştırılması

Pages
91–99
Publication Date
2022-11-05
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Inspired and expired anesthetic concentrations were found to be decreased significantly in the 10 mL kg-1 min-1 flow groups when compared to the 20 and 30 mL kg-1 min-1 flow groups (p

📌 3 Key Takeaways

🎯
Objective & Hypothesis:In this study, we aimed to examine the effects of fresh gas flow (FGF) adjusted to the body weight (10-20-30 mL kg-1 min-1) in patients undergoing low flow anesthesia either with isoflurane or desflurane on hemodynamics, body temperature, concentration of oxygen and anesthetic gases.
📊
Key Findings & Data:Then these basic groups were randomly divided into 3 subgroups to receive 10, 20 or 30 mL kg-1 min-1 FGF.
💡
Conclusion & Impact:Inspired and expired anesthetic concentrations were found to be decreased significantly in the 10 mL kg-1 min-1 flow groups when compared to the 20 and 30 mL kg-1 min-1 flow groups (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

In this study, we aimed to examine the effects of fresh gas flow (FGF) adjusted to the body weight (10-20-30 mL kg-1 min-1) in patients undergoing low flow anesthesia either with isoflurane or desflurane on hemodynamics, body temperature, concentration of oxygen and anesthetic gases. Sixty ASA I-II adult patients undergoing elective surgical procedures were included into the study. Patients were randomly allocated into two basic groups to receive either isoflurane or desflurane. Then these basic groups were randomly divided into 3 subgroups to receive 10, 20 or 30 mL kg-1 min-1 FGF. After standard anesthetic induction and intubation, during the first 10 minutes, FGF was 4 L min-1 with isoflurane 1.5 % or desflurane 6 % in 50% oxygen and 50 % nitrous oxide. Then concentrations of isoflurane and desflurane were set as 2 % and 8 % respectively and FGF was adjusted according to the groups. Heart rate (HR), mean arterial pressure (MAP), SpO2, esophageal temperature, vaporizer settings, inspired and expired anesthe tic concentrations were recorded at regular intervals throughout the study. Inspired and expired anesthetic concentrations were found to be decreased significantly in the 10 mL kg-1 min-1 flow groups when compared to the 20 and 30 mL kg-1 min-1 flow groups (p

Özet

Çalışmamızda, vücut ağırlığına göre (10-20-30 mL kg-1 dk-1) hesaplanan taze gaz akımı ile uygulanan izofluran ve desfluranın hemodinami, vücut ısısı, oksijen ve kullanılan anestezik gaz konsantrasyonları üzerine etkisinin araştırılması amaçlandı. Etik kurul ve hasta onayı alındıktan sonra, elektif cerrahi geçirecek ASA I-II 60 erişkin olgu rasgele olarak izofluran ve desfluran uygulanan iki gruba ve bu iki grup da 10, 20 ve 30 mL kg-1 dk-1 taze gaz akımı uygulanan 10'ar olgu içeren 3 alt gruba ayrıldı. Standart anestezi indüksiyonundan ve entübasyondan sonra ilk 10 dk taze gaz akımı 4 L dk-1 (%50 O2:N2O) izofluran % 1.5 ve desfluran % 6 olarak uygulandı. Başlangıç fazı sonrasında izofluran % 2 ve desfluran % 8 konsantrasyona ve taze gaz akımı hızları ise gruplara göre ayarlandı. KAH, OAB, SpO2; ösefagus ısısı, vaporizör ayarı konsantrasyonu, inspire ve ekspire edilen oksijen ve gaz konsantrasyonu çalışma protokolüne göre belirli aralıklarla kaydedildi. İnspire ve ekspire edilen gaz konsantrasyonu 10 mL kg-1 dk-1 akım gruplarında diğer gruplara göre anlamlı azaldı (p

🔖

Cite This Article

ERSOY, M. Ö., KARAASLAN, K., KÖROĞLU, A., TOĞLA, T., AYAS, A., DEMİRBİLEK, S., GEDİK, E. (2022). Comparison of the fresh gas flows adjusted to the body weights in patients undergoing low flow anaesthesia either with isoflurane or desflurane. Türk Anestezi ve Reanimasyon Dergisi, Cilt: 32 - Sayı: 2, 91–99. https://ajindex.com/articles/620208

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (19)

  1. Baum JA, Nunn G. Low flow anaesthesia: The theory and practice of low flow, minimal flow and closed system anaesthesia. 2nd ed, Oxford: Butterworth-Heinemann; 2001. p241-245
  2. Baum J. Low flow anaesthesia with Drager machines. Lübeck; Dragerwerk AG 1993; 6-65
  3. Arkan A, Kuvaki B. Azaltılmış taze gaz akımlı anestezi yöntemleri. Anestezi Dergisi 2001; 9:1-18
  4. Baum J. Clinical applications of low flow and closed circuit anaesthesia. Acta Anaesthesiol Belg 1990; 41:239- 247
  5. Couto De Silva JM, Aldrete JA. A proposal for a new classification of anaesthetic gas flows. Acta Anaesthesiol Belg 1990; 41:253-258 6. Couto De Silva JM. Systolic arterial pressure as a monitor of depth of anaesthesia. Br J Anacsth 1991; 67:506
  6. Kleemann PP. The climatisation of anaesthetic gases under conditions of high flow to low flow. Acta Anaesthesiol Belg 1990; 41:189-200
  7. Eger II El. The pharmacology of isoflurane Br J Anaesth 1984; 56(suppl):7IS-99S
  8. Tomatır E, Sabuncu C, Şentürk Y. İnhalasyon anestezisinde güncel yöntem: kapalı devre. Anestezi Dergisi 1997; 5:95-100
  9. Baum JA. Low-flow anaesthesia: The sensible and judicious use of inhalation anaesthetics. Acta Anaesthesiol Scand 1997; 41(suppl):264-267
  10. Baum JA, Aitkenhead AR. Low-flow anaesthesia. Anaesthesia 1995; 50(suppl):37-44
  11. Lowe HJ, Viljoen JF. Nomogram for anaesthetic uptake. Anacsth Intens Care 1994; 22:374-375
  12. Baum J. Klinische anwendung der minimal-flow- anasthesie. In Jantzen JPAH and Kleeman PP, eds, Narkoscbeatmung. Low-flow, minimal-flow, geschlosse- nes system. Stutgard: Schattaucr; 1989. p 49-66
  13. Lin CY. Uptake of anaesthetic gases and vapours. Anaesth Intens Care 1994; 22:363-73
  14. Eger El II. Complexities overlooked: things may not be what the seem. Anesth Analg 1997; 84:239-240
  15. Baxter AD. Low and minimal flow inhalational anaesthesia. Can J Anaesth 1997; 44:643-653
  16. Baum JA. Low flow anaesthesia. Eur J Anaesthesiol 1996; 13:432-435
  17. Eger El II. Desflurane animal and human pharmacol ogy: aspects of kinetics, safety, and MAC. Anesth Analg 1992; 75:4(Suppl):S 3-7:S 8-9 19. Beatty PCW, Kay B, Healy TEJ. Measurement of the rates of nitrous oxide/oxygen anaesthesia uptake and nitrogen excretion in man. Br J Anaesth 1984; 56:223- 232
  18. Smith TC. Nitrous oxide and low flow inflow circle systems. Anesthesiology 1966; 27:266-271
  19. Baum JA. Düşük Akımlı Anestezi (Çev.Edit.Tomatır E.). Klinik uygulamada düşük akımlı anestezi, İstanbul: Nobel Tıp Kitabevi; 2