Journals / Türk Anestezi ve Reanimasyon Dergisi / 2004 / Cilt: 32 - Sayı: 6

Hashimoto's encephalopathy with psychiatric symptome requiring intensive care therapy

Psikiyatrik bulgularla seyreden ve yoğun bakım takibi gerektiren bir haşimoto ensefalopatisi

Pages
479–483
Publication Date
2022-11-05
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

No complication was seen during intra- and postoperative periods.In conclusion, we think that spinal anaesthesia is a safe and effective anaesthetic technique for patients treated with bleomycin.

📌 3 Key Takeaways

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Objective & Hypothesis:It has been reported that high oxygen concentration during anaesthesia can increase pulmonary toxicity in patients treated with bleomycine.
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Key Findings & Data:We report the succesful spinal anaesthetic management of a patient who had been treated with bleomycin.A 30 year-old man with a history of mixed germ cell testicular carcinoma post resectıon received seven courses of bleomycin therapy.
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Conclusion & Impact:No complication was seen during intra- and postoperative periods.In conclusion, we think that spinal anaesthesia is a safe and effective anaesthetic technique for patients treated with bleomycin.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

It has been reported that high oxygen concentration during anaesthesia can increase pulmonary toxicity in patients treated with bleomycine. We report the succesful spinal anaesthetic management of a patient who had been treated with bleomycin.A 30 year-old man with a history of mixed germ cell testicular carcinoma post resectıon received seven courses of bleomycin therapy. Following bleomycin therapy, local recurrence developed in his scrotum and the patient required a second operation. Spinal anaesthesia was preferred over general anesthesia and 500 mL Ringer Lactate was infused before anaesthesia. With the patient in lateral decubitis position, a 25 gauge spinal needle was inserted through the L3-4 intervertebral space. After correct placement of the spinal needle, 15 mg of 0.5 % hyperbaric bupivacaine was administered. Hemodynamic and respiratory parameters were recorded during the operation. Nasal-oxygen was not used during intra- and postoperative periods because of bleomycin induced pulmonary toxicity. No complication was seen during intra- and postoperative periods.In conclusion, we think that spinal anaesthesia is a safe and effective anaesthetic technique for patients treated with bleomycin.

Özet

Haşimoto ensefalopatisi, klinik olarak konfüzyon, konvülsiyonlar, bilinçte değişiklikler, "stroke" benzeri epizodlar, miyoklonus ve tremor ile karakterizedir. Patogenez bilinmemekte fakat otoimmün bir serebral disfonksiyon olarak değerlendirilmektedir. Tiroid disfonksiyonu her olguda görülmeyebilir. Biz, çocuklarının doğumunu takiben depresyon gelişmiş, 38 yaşında kadın bir olguyu sunuyoruz. Hasta, ikinci depresyonu takiben amnezi, paranoid psikoz, ardından somnolans gelişen jeneralize konvülsiyonlar, ajitasyon ve deliryum ile psikiyatri kliniği'ne yatırıldı. Daha sonra hasta, jeneralize konvülsiyonlarının yeterince kontrol edilememesi nedeniyle Nöroşirürji Yoğun Bakım Ünitesi'ne alındı. EEG'de diffüz biyoelektriksel aktivite gecikmesi gözlendi ve kranial MR normaldi. Tanısal araştırmalarda infeksiyöz nedenler ekarte edildi. Plazma Anti-tiroid peroksidaz ve Anti-tiroglobulinde yükselme ile tiroid hormon düzeylerinin normal olması, Haşimoto ensefalopatisi için pozitif bulgular olarak değerlendirildi. Günde 120 mg prednisolon tedavisine başlandı ve dozu giderek azaltılarak onuncu günde 40 mg'a inildi. Hasta, klinik durumda belirgin iyileşme ile plazma Anti-tiroid peroksidaz ve Anti-tiroglobulin düzeylerinde azalma olması üzerine servise çıkarıldı. Hasta on gün sonra nörolojik defisitsiz taburcu edildi.

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Cite This Article

YALÇINKAYA, C., TÜRECİ, E., KAYAALP, L., YENTÜR, E. (2022). Hashimoto's encephalopathy with psychiatric symptome requiring intensive care therapy. Türk Anestezi ve Reanimasyon Dergisi, Cilt: 32 - Sayı: 6, 479–483. https://ajindex.com/articles/620164

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