Journals / Türk Anestezi ve Reanimasyon Dergisi / 2005 / Cilt: 33 - Sayı: 6

Bupivacaine related toxic reaction: Convulsion and permanent coma

Bupivakaine bağlı toksik reaksiyon: Konvülziyon ve kalıcı şuur kaybı

Pages
490–493
Publication Date
2022-11-05
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

This case is reported, as we could not find a study informing a patient who stayed unconscious and progressed such a convulsion, which was repetitive in a long time period due to intravenous bupivacaine administration.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Bupivacaine is a long-acting local anaesthetic frequently used for long rocedures or those associated with significant postprocedure pain.
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Key Findings & Data:The patient remained unconscious for 150 days in the intensive care unit.
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Conclusion & Impact:This case is reported, as we could not find a study informing a patient who stayed unconscious and progressed such a convulsion, which was repetitive in a long time period due to intravenous bupivacaine administration.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Bupivacaine is a long-acting local anaesthetic frequently used for long rocedures or those associated with significant postprocedure pain. The central nervous and cardiovascular system side effects of bupivacaine are well described. In this report we descreibe a patient who devolped generalized convulsions during accidental intravascular bupivacaine administration for the purpose of brachial plexus blockade. The patient remained unconscious for 150 days in the intensive care unit. This case is reported, as we could not find a study informing a patient who stayed unconscious and progressed such a convulsion, which was repetitive in a long time period due to intravenous bupivacaine administration.

Özet

Bupivakain etki süresinin uzun olması nedeniyle belirgin postoperatif ağrı ile birlikte uzun süreli operasyonlarda tercih edilen bir lokal anestetiktir. Santral sinir sistemi ve kardiyovasküler sistem toksisitesi çok iyi tarif edilmiştir. Bu yazıda, brakiyal pleksus blokajı sırasında bupivakainin yanlışlıkla intravasküler yolla verilmesine bağlı olarak jeneralize konvülziyon gelişen ve yoğun bakımda yattığı 150 gün boyunca şuuru kapalı olarak takip edilen bir olgu sunulmuştur. Literatürde lokal anestezik toksisitesi nedeniyle uzun süre tekrarlayan konvülziyon atakları geçiren ve şuuru açılmayan bir olguya rastlamadığımız için bu olguyu sunmaktayız.

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Cite This Article

DORA, B., YILMAZ, M., HADİMİOĞLU, N., DÖŞEMECİ, L., CENGİZ, M., YEĞİN, A., RAMAZANOĞLU, A. (2022). Bupivacaine related toxic reaction: Convulsion and permanent coma. Türk Anestezi ve Reanimasyon Dergisi, Cilt: 33 - Sayı: 6, 490–493. https://ajindex.com/articles/620161

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