Journals / Türk Anestezi ve Reanimasyon Dergisi / 2005 / Cilt: 33 - Sayı: 1

Metoclopramide-induced akathisia (Case report)

Metoklopramide bağlı akatizi

Pages
82–85
Publication Date
2022-11-05
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In this article we reported a case of akathisia after administration of intravenous metoclopramide for antiemetic therapy.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Metoclopramide, a dopamine-2 receptor antagonist, may cause or exacerbate a variety of extrapyramidal movement disorders such as akathisia.
📊
Key Findings & Data:Akathisia is a psychoneuromotor phenomena that is defined as an inner feeling of restlessness, an inability to sit still, and a compulsion to move about.
💡
Conclusion & Impact:In this article we reported a case of akathisia after administration of intravenous metoclopramide for antiemetic therapy.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Metoclopramide, a dopamine-2 receptor antagonist, may cause or exacerbate a variety of extrapyramidal movement disorders such as akathisia. Akathisia is a psychoneuromotor phenomena that is defined as an inner feeling of restlessness, an inability to sit still, and a compulsion to move about. The clinical phenomena, which may be is underdiagnosed or underappreciated by clinicians may progress and become life-threateaning. In this article we reported a case of akathisia after administration of intravenous metoclopramide for antiemetic therapy.

Özet

Dopamin-2 reseptör antagonisti olan metoklopramid, akatizi gibi çeşitli ekstrapiramidal sistem bozukluklarına yol açabilir. Akatizi, bunaltıcı bir hareket etme zorunluluğu hissi ve oturmama ya da hep ayakta olma şeklinde tanımlanan bir psikonöromotor fenomendir. Sonu bazen suisitle sonuçlanabilecek kadar ciddi seyredebilen, klinisyenlerce çoğu zaman atlanan veya ciddiye alınmayan bu klinik tablonun, bir olgu nedeniyle vurgulanması amaçlanmıştır. Bu makalede antiemetik amaçla yapılan intravenöz metoklopramid sonrası gelişen bir akatizi vakası sunulmuştur.

🔖

Cite This Article

DİKMEN, B., CEYHAN, A., UYSAL, Y. H., TAKMAZ, A. S., ÖZEN, M. (2022). Metoclopramide-induced akathisia (Case report). Türk Anestezi ve Reanimasyon Dergisi, Cilt: 33 - Sayı: 1, 82–85. https://ajindex.com/articles/620140

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (17)

  1. Yamamoto M, Ujike H, Ogawa N. Metoclopramide-induced parkinsonisms. Clin Neuropharmacol 1987; 10:287-289
  2. LaGorio J, Thompson V A, Sternberg D, Dorje P. Akathisia and Anesthesia: Refusal of Surgery After The Administration of Metoclopramide. Anesth Analg 1998; 87:224-227
  3. Hyser CL, Drake ME Jr. Myoclonus induced by metoclopramide therapy. Arch Intern Med 1983; 143:2201-2202
  4. Hales R, Yudofsky S, Talbott J (eds). Textbook of psychiatry. 3rd edition. Washington DC, American Psychi¬atric press; 1999; 1069
  5. Yüksel N. Psikofarmakoloji. 2. basım. ANKARA:Çizgi Tıp Yayınevi 2003; 111-115
  6. Blaisdel GD. Akathisia:a comprehensive review and treatment summary. Pharmacopsychiatry 1994; 27:139-146
  7. Physician's Desk Reference. 56th Ed Montvale, New Jersy: Medical Economics co, Inc; 2002; 2935-2943
  8. Borenstein P, Bles G. Effects cliniques et electroencep-halographiques du metoclopramide en psychiatrie. Thera-pie 1965; 29:975-995
  9. Miller RG, Jankovic J. Metoclopramide-induced mo¬vements disorders. Clinical findings with a review of the literature. Arch Int Med 1989; 149:2486-2492
  10. Jungman E, Schoffling K. Akathisia and metoclopra¬mide. Lancet 1982; 11:221
  11. Fleishman SB, Lavin MR, Sattler M, Szarka H. An-tiemetic-induced akathisia in cancer patients receiving che¬motherapy. Am J Psychiat 1994; 151:763-765
  12. Drake RE, Ehrlih J. Suicide attempts associated with akathisia. Am J Psychiatry 1985; 142:499-501
  13. Chow LY, Chung D, Leung V, Leung TF, Leung CM. Suicide attempt due to metoclopramide-induced akathisia. Int J Clin Pract 1997; 51:330-331
  14. Batemen DN, Kahn C, Davies DS. Concentration ef¬fect studies with oral metoclopramide. Br J Clin Pharmacol 1979; 8:179-182
  15. Strum SB, Mc Dermed JE, Op fell RW, Riech LP. Intravenous metoclopramide. An effective antiemetic in cancer chemotherapy. JAMA 1982; 21:247:2683-2689
  16. Beightol RW, Coupal JJ, Shih W-J. Prevention of metoclopramide-induced akathisia during gastric emptying imaging. J Nucl Med 1991; 32:1644-1649
  17. Yüksel N. Psikofarmakoloji. 2. basım. ANKARA Çizgi Tıp Yayınevi 2003; 173-178.