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Journals / Türk Anestezi ve Reanimasyon Dergisi / 2005 / Cilt: 33 - Sayı: 2

Maternal and neonatal effects of remifentanil used for endotracheal intubation in caesarean section

Sezaryenlerde endotrakeal entübasyon için kullanılan remifentanilin anne ve yenidoğandaki etkileri

Nejat NARLI
Hakkı ÜNLÜGENÇ
Geylan IŞIK
Salih AĞAR
Mehmet ÖZALEVLİ
Murat GÜNDÜZ
Pages
163–170
Publication Date
2022-11-05
DOI
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⚡ TL;DR(Too Long; Didn't Read)

New-borns' performance were assessed using APGAR and neuro adaptive capacity scores (NACS).Results: Intubation conditions were significantly better in group R3 and S than in group R2 (p

📌 3 Key Takeaways

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Objective & Hypothesis:Aim: This prospective, randomised, double-blinded study was performed to compare intubating conditions, maternal and neonatal effects of remifentanil used for endotracheal intubation in caesarean section with succinylcholine.Materials and Methods: Following Faculty ethic committee approval and written informed consent of parturients, ninety-six parturient were assigned randomly to one of three groups.
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Key Findings & Data:After intravenous administration of atropine 0.5 mg, anaesthesia was induced with thiopental sodium (5 mg kg-1) followed by remifentanil 2,5 µg kg-1 (Group R2) (n=32), remifentanil 3 µg kg-1 (Group R3) (n=32) over 60 seconds or succinylcholine 1.5 mg kg-1 (Group S) (n=32).
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Conclusion & Impact:New-borns' performance were assessed using APGAR and neuro adaptive capacity scores (NACS).Results: Intubation conditions were significantly better in group R3 and S than in group R2 (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Aim: This prospective, randomised, double-blinded study was performed to compare intubating conditions, maternal and neonatal effects of remifentanil used for endotracheal intubation in caesarean section with succinylcholine.Materials and Methods: Following Faculty ethic committee approval and written informed consent of parturients, ninety-six parturient were assigned randomly to one of three groups. After intravenous administration of atropine 0.5 mg, anaesthesia was induced with thiopental sodium (5 mg kg-1) followed by remifentanil 2,5 µg kg-1 (Group R2) (n=32), remifentanil 3 µg kg-1 (Group R3) (n=32) over 60 seconds or succinylcholine 1.5 mg kg-1 (Group S) (n=32). Intubating conditions and haemodynamic parameters were recorded. Preoperatively and after umbilical cord clamping, maternal blood samples were taken to evaluate plasma renin, glucose, and cortisol, and neonatal umbilical cord blood samples were taken to evaluate blood gas values. New-borns' performance were assessed using APGAR and neuro adaptive capacity scores (NACS).Results: Intubation conditions were significantly better in group R3 and S than in group R2 (p

Özet

Amaç: Prospektif, randomize çift-kör çalışmamız; sezaryenlerde endotrakeal entübasyon için kullanılan remifentanil'in entübasyon kalitesi, anne ve yenidoğandaki etkilerini süksinilkolin ile karşılaştırmak amacıyla planlandı.Gereç ve Yöntem: Fakülte etik kurul ve anne adaylarının yazılı onayı alınarak doksan altı anne adayı rastgele 3 gruba ayrıldı. İntravenöz 0.5 mg atropin uygulamasını takiben, 5 mg kg-1 tiyopental sodyum ile anestezi indüksiyonu sağlandı. Birinci gruba remifentanil 2,5 µg kg-1 (Grup R2) (n=32), ikinci Gruba remifentanil 3 µg kg-1 (Grup R3) (n=32) ve üçüncü gruba süksinilkolin 1,5 mg kg-1 (Grup S) (n=32) uygulandı. Entübasyon kalitesi ve hemodinamik parametreler kaydedildi. Preoperatif ve göbek kordonu klemplenmesini takiben plazma renin, glikoz ve kortizol ölçümü için anneden, göbek kordonunun kan gazı ölçümü için ise yenidoğandan kan örnekleri alındı. Yenidoğanlar APGAR ve nöro-adaptif kapasite skoru (NAKS) ile değerlendirildi.Bulgular: Entübasyon kalitesi grup R3 ve S'de, grup R2'ye göre istatistiksel olarak daha iyi bulundu (p

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Cite This Article

NARLI, N., ÜNLÜGENÇ, H., IŞIK, G., AĞAR, S., ÖZALEVLİ, M., GÜNDÜZ, M. (2022). Maternal and neonatal effects of remifentanil used for endotracheal intubation in caesarean section. Türk Anestezi ve Reanimasyon Dergisi, Cilt: 33 - Sayı: 2, 163–170. https://ajindex.com/articles/620133

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