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Journals / Türk Anestezi ve Reanimasyon Dergisi / 2005 / Cilt: 33 - Sayı: 1

Comparison of effects of sevoflurane and high-dose fentanyl anesthesia on hemodynamic profile and postoperative recovery in coronary artery surgery

Koroner arter cerrahisinde, sevofluran ve yüksek doz fentanil anestezilerinin, hemodinami ve postoperatif derlenme üzerine etkilerinin karşılaştırılması

Nesrin TURAN
Cavidan ARAR
Veli YORULMAZ
Zafer PAMUKÇU
Pages
61–68
Publication Date
2022-11-05
DOI
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Time of spontaneous eye opening, orientation, extubation and the length of intensive care unit stay were recorded as recovery criteria.Results: In Group I heart rate increased after intubation, left ventricle stroke work and index decreased at all measurements (p

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Objective & Hypothesis:Aim: Hemodynamic and recovery characteristics of two anesthetic techniques were compared in patients undergoing CABG.Materials and Methods: After the approval of Ethics Committee, 55 patients were randomized in: Group I (n=28) to receive intravenous diazepam 0.2 mg kg-1, pancuronium 0.1 mg kg-1 and fentanyl 10 µg kg-1, and Group II (n=27) to receive diazepam 0.2 mg kg-1, pancuronium 0.1 mg kg-1 and fentanyl 50 µg kg-1 for induction.
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Key Findings & Data:Anesthesia was maintained with 2 % end-tidal sevoflurane and fentanyl 5 µg kg-1 in Group I; with fentanyl 15 µg kg-1 in Group II.
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Conclusion & Impact:Time of spontaneous eye opening, orientation, extubation and the length of intensive care unit stay were recorded as recovery criteria.Results: In Group I heart rate increased after intubation, left ventricle stroke work and index decreased at all measurements (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Aim: Hemodynamic and recovery characteristics of two anesthetic techniques were compared in patients undergoing CABG.Materials and Methods: After the approval of Ethics Committee, 55 patients were randomized in: Group I (n=28) to receive intravenous diazepam 0.2 mg kg-1, pancuronium 0.1 mg kg-1 and fentanyl 10 µg kg-1, and Group II (n=27) to receive diazepam 0.2 mg kg-1, pancuronium 0.1 mg kg-1 and fentanyl 50 µg kg-1 for induction. Anesthesia was maintained with 2 % end-tidal sevoflurane and fentanyl 5 µg kg-1 in Group I; with fentanyl 15 µg kg-1 in Group II. Hemodynamic measurements were recorded before and after induction and intubation, after incision and sternotomy, before aortic cannulation, 15 minutes after removal from pump, at the end of surgery, at 2nd hour postoperatively. Time of spontaneous eye opening, orientation, extubation and the length of intensive care unit stay were recorded as recovery criteria.Results: In Group I heart rate increased after intubation, left ventricle stroke work and index decreased at all measurements (p

Özet

Amaç: Çalışmamızda koroner arter cerrahisi geçirecek olgularda iki anestezi tekniğinin, hemodinami ve postoperatif derlenme üzerine etkileri karşılaştırıldı.Gereç ve Yöntem: Etik kurul onayı sonrası, 55 olgu rasgele iki gruba ayrıldı. Grup I'e (n=28) indüksiyonda 0.2 mg kg-1 diazepam, 0.1 mg kg-1 pankuronyum, 10 µg kg-1 fentanil iv; Grup II'ye (n=27) 0.2 mg kg-1 diazepam, 0.1 mg kg-1 pankuronyum, 50 µg kg-1 fentanil 4-5 dakikada iv uygulandı. İdamede Grup I'de end tidal % 2 sevofluran ve 5 µg kg-1 fentanil iv; Grup II'de 15 µg kg-1 fentanil iv uygulandı. Hemodinamik parametreler indüksiyondan önce ve sonra, entübasyondan, insizyondan ve sternotomiden sonra, aort kanülasyonundan önce, pompa çıkışı 15. dk., cerrahi bitimi ve postoperatif 2. saatte kaydedildi. Postoperatif derlenme kriterleri olarak; spontan göz açma, oriyantasyon, ekstübasyon ve yoğun bakım ünitesinde kalış zamanları kaydedildi.Bulgular: Kalp tepe atımı entübasyon sonrasında Grup I'de anlamlı olarak yükseldi, sol ventrikül atım işi ve sol ventrikül atım iş indeksi tüm ölçümlerde başlangıçtakinden düşük bulundu (p

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Cite This Article

TURAN, N., ARAR, C., YORULMAZ, V., PAMUKÇU, Z. (2022). Comparison of effects of sevoflurane and high-dose fentanyl anesthesia on hemodynamic profile and postoperative recovery in coronary artery surgery. Türk Anestezi ve Reanimasyon Dergisi, Cilt: 33 - Sayı: 1, 61–68. https://ajindex.com/articles/620127

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