Journals / Türk Anestezi ve Reanimasyon Dergisi / 2006 / Cilt: 34 - Sayı: 2

Anesthesia with remifentanil combined with sevoflurane, desflurane or propofol: Comparison of recovery characteristics, complications and the cost of anesthetics

Remifentanil ile kombine edilen sevofluran, desfluran veya propofol anestezisi: Derlenme özellkilerinin, komplikasyonların ve anestezik ilaç maliyetlerinin karşılaştırılması

Pages
103–110
Publication Date
2022-11-05
DOI
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⚡ TL;DR(Too Long; Didn't Read)

Early recovery times (times to spontaneous breathing, eye opening, extubation, orientation and transfer to postanesthesia care unit), postanesthesia recovery scores (Modified Aldrete Scores) and anesthesia-related complications were evaluated during the immediate postoperative period.Results: Overall early recovery times were significantly shorter in Group D compared with the other two treatment groups (p value ranges: 0.05-0.001).

📌 3 Key Takeaways

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Objective & Hypothesis:Aim: In this study, we purposed to compare desflurane, sevoflurane, and propofol with respect to their effect on early recovery characteristics, anesthesia-related complications and the cost of anesthetics when combined with remifentanil for the maintenance of anesthesia.Materials and Methods: Sixty women undergoing abdominal hysterectomy were randomly assigned to one of the three treatment groups.
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Key Findings & Data:After standardized induction of anesthesia and tracheal intubation sequence, anesthesia was maintained with either sevoflurane 0.5-2 % (Group S), desfurane 2-6 % (Group D), or propofol 50-150 µg kg-1 min-1 (Group P) in combination with remifentanil 0.125-0.25 µgr kg-1 min-1 and nitrous oxide 60 % in oxygen.
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Conclusion & Impact:Early recovery times (times to spontaneous breathing, eye opening, extubation, orientation and transfer to postanesthesia care unit), postanesthesia recovery scores (Modified Aldrete Scores) and anesthesia-related complications were evaluated during the immediate postoperative period.Results: Overall early recovery times were significantly shorter in Group D compared with the other two treatment groups (p value ranges: 0.05-0.001).
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Aim: In this study, we purposed to compare desflurane, sevoflurane, and propofol with respect to their effect on early recovery characteristics, anesthesia-related complications and the cost of anesthetics when combined with remifentanil for the maintenance of anesthesia.Materials and Methods: Sixty women undergoing abdominal hysterectomy were randomly assigned to one of the three treatment groups. After standardized induction of anesthesia and tracheal intubation sequence, anesthesia was maintained with either sevoflurane 0.5-2 % (Group S), desfurane 2-6 % (Group D), or propofol 50-150 µg kg-1 min-1 (Group P) in combination with remifentanil 0.125-0.25 µgr kg-1 min-1 and nitrous oxide 60 % in oxygen. Early recovery times (times to spontaneous breathing, eye opening, extubation, orientation and transfer to postanesthesia care unit), postanesthesia recovery scores (Modified Aldrete Scores) and anesthesia-related complications were evaluated during the immediate postoperative period.Results: Overall early recovery times were significantly shorter in Group D compared with the other two treatment groups (p value ranges: 0.05-0.001). However, there were no significant differences between Group S and Group P regarding these recovery parameters. Total cost of the anesthetics was found to be similar in the three groups.Conclusion: Abdominal hysterectomy patients anesthetized with desflurane had shorter postanesthesia recovery times than that of sevoflurane and propofol. Further, anesthesia with desflurane may increase turnover of operating room and productivity due to its early recovery properties.

Özet

Amaç: Çalışmamızda; anestezi idamesinde remifentanil ile kombine edilen desfluran, sevofluran ve propofolün erken derlenme kriterleri, anesteziye bağlı komplikasyonlar ve anestezik ajan maliyetleri üzerine olan etkilerini karşılaştırmayı amaçladık.Gereç ve Yöntem: Abdominal histerektomi geçirecek 60 kadın olgu, 3 çalışma grubundan birine seçilecek şekilde randomize edildiler. Standart anestezi indüksiyonu ve trakeal entübasyonu takiben, anestezi idamesi; % 0.5-2 sevofluran (Group S), % 2-6 desfuran (Group D) veya 50-150 µg kg-1 dk-1 propofolden (Group P) herhangi birisinin 0.125-0.25 µg kg-1 dk-1 remifentanil ve oksijen içinde % 60 azot protoksit ile kombine edilmesiyle sağlandı. Olgular; erken derlenme zamanları (spontan solunum, göz açma, ekstübasyon, oryantasyon ve postoperatif derlenme ünitesine transport zamanları), anestezi sonrası derlenme skorları (Modifiye Aldrete Skoru) ve anesteziye bağlı komplikasyonlar açısından erken postoperatif dönemde değerlendirildiler.Bulgular: Diğer iki grup ile karşılaştırıldığında Grup D'de, tüm erken derlenme zamanları anlamlı olarak daha kısa bulundu (p değeri sınırları: 0.05-0.001). Postoperatif derlenme kriterleri açısından Grup S ile Grup P arasında herhangi bir anlamlı farklılık bulunmadı. Toplam anestezik ilaç maliyetleri açısından üç grup benzer olarak bulundu.Sonuç: Desfluran ile anestezi uygulanan abdominal histerektomi olguları, sevofluran ve propofol uygulanan olgulara göre daha kısa derlenme zamanlarına sahipti. Bununla birlikte, erken derlenme özelliklerinden dolayı desfluran kullanımı, ameliyathane sirkülasyonunu ve verimliliğini artırabilir.

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Cite This Article

TÜRKER, G., TÜFEK, A., ÖZCAN, B., BİLGİN, H. (2022). Anesthesia with remifentanil combined with sevoflurane, desflurane or propofol: Comparison of recovery characteristics, complications and the cost of anesthetics. Türk Anestezi ve Reanimasyon Dergisi, Cilt: 34 - Sayı: 2, 103–110. https://ajindex.com/articles/620050

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