Journals / Türk Anestezi ve Reanimasyon Dergisi / 2007 / Cilt: 35 - Sayı: 3

Localized urticarial reaction to intravenous meperidine

İntravenöz meperidin ile gelişen lokalize ürtikeryal reaksiyon

Pages
212–215
Publication Date
2022-11-05
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In this case, possible allergy mechanisms and treatment steps of synthetic opioid meperidine were discussed in which acute localized urticarial reactions were observed with meperidine administration due to postoperative shivering.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Despite the histamine releasing effects of opioid, allergic reactions were rare.
📊
Key Findings & Data:Meperidine, a synthetic opioid, is widely used for prcmedication in preoperativc period and for analgesia in postoperative period.
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Conclusion & Impact:In this case, possible allergy mechanisms and treatment steps of synthetic opioid meperidine were discussed in which acute localized urticarial reactions were observed with meperidine administration due to postoperative shivering.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Despite the histamine releasing effects of opioid, allergic reactions were rare. Meperidine, a synthetic opioid, is widely used for prcmedication in preoperativc period and for analgesia in postoperative period. Meperidine could cause direct dcgranulation in mast cells without specific IgE antibodies. Allergic reactions from local urticarial reactions to anaphylaxis could be seen. In this case, possible allergy mechanisms and treatment steps of synthetic opioid meperidine were discussed in which acute localized urticarial reactions were observed with meperidine administration due to postoperative shivering.

Özet

Opioidlerin histamin salıcı etkilerine rağmen, alerjik reaksiyonları enderdir. Meperidin hem preopreratif dönemde premedikasyon amacı ile hem de postoperatif dönemde analjezi sağlamak amacı ile yaygın olarak kullanılmaktadır. Sentetik bir opioid olan meperidin spesifik IgE antikorları olmadan da mast hücrelerinde doğrudan degranülasyona neden olabilmektedir. Mcperidine bağlı lokalize ürtikeryal reaksiyonlardan anaflaksiye kadar alerjik reaksiyonlar gelişebilir. Bu olgu ile önceden bilinen bir alerji öyküsü olmayan bir hastada postoperatif titreme nedeni ile meperidin uygulaması ile akut gelişen lokalize ürtikeryal reaksiyon olası alerji mekanizmaları ve tedavi basamakları tartışıldı.

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Cite This Article

YILMAZ, A. A., SERDAROĞLU, H., DURU, B., YALÇIN, Ş., AŞIK, İ. (2022). Localized urticarial reaction to intravenous meperidine. Türk Anestezi ve Reanimasyon Dergisi, Cilt: 35 - Sayı: 3, 212–215. https://ajindex.com/articles/620046

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