Journals / Türk Anestezi ve Reanimasyon Dergisi / 2007 / Cilt: 35 - Sayı: 3

Anaphylactic reaction to lansoprazole

Lansoprazole karşı anaflaktik reaksiyon

Pages
209–211
Publication Date
2022-11-05
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Since anaphylaxis is a potentially serious reaction, more precise information is needed regarding its frequency, and healthcare professionals need to be aware of this possibility when prescribing these agents.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Lansoprazole is a substituted benzimidazole that has gained widespread use in the treatment of acidic and peptic ulcer disease.
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Key Findings & Data:Skin inflammation, urticaria, pruritus, alopecia, and dry skin have been reported in 0.5- 1.5 % of patients.
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Conclusion & Impact:Since anaphylaxis is a potentially serious reaction, more precise information is needed regarding its frequency, and healthcare professionals need to be aware of this possibility when prescribing these agents.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Lansoprazole is a substituted benzimidazole that has gained widespread use in the treatment of acidic and peptic ulcer disease. Adverse events with the drug are rare and involve mainly the gastrointestinal and central nervous systems. Skin inflammation, urticaria, pruritus, alopecia, and dry skin have been reported in 0.5- 1.5 % of patients. We report a case of a 56-ycar-old man with peptic ulcers who developed periorbital edema, edema of the skin, generalized pruritis and urticaria, a swollen tonque, increase sweating and loss of conciousness. These findings suggest that the chemically related lansoprazole can, as a group, cause anaphylactic reactions; however, the rate is comparatively low. Since anaphylaxis is a potentially serious reaction, more precise information is needed regarding its frequency, and healthcare professionals need to be aware of this possibility when prescribing these agents.

Özet

Benzimidazol içeren lansoprazolun, pcptik ülser ve gastrik asit hastalıklarının tedavisinde kullanımı artmaktadır. İlaç ile yan etki ender olup, çoğunlukla gastrointestinal ve santral sinir sistemini kapsar. Deri inflamasyonu, ürtiker, kaşıntı, saç dökülmesi, deride kuruma gibi yan etkiler hastalarda % 0.5-1.5 olarak rapor edilmiştir. Bu olgu sunumumuzda, 56 yaşında peptik ülseri olan erkek hastada oral lansoprazol alımı ile gelişen periorbital ödem, deride ödem, yaygın kaşıntı ve ürtiker, dilde şişme, aşırı terleme ve bilinç kaybını bildirdik. Lansoprazole bağlı gelişen anaflaktik reaksiyon, düşük oranda olsa da anaflaksi ciddi bir reaksiyondur. Hekimler ilacı reçete ederken, lansoprazol kullanımında anaflaksi gelişme olasılığı olduğunu farkında olmaları gerekmektedir.

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Cite This Article

HEKİMOĞLU, S., YANDIM, T., VATAN, İ., KARAÇAYIR, Y., MEMİŞ, D. (2022). Anaphylactic reaction to lansoprazole. Türk Anestezi ve Reanimasyon Dergisi, Cilt: 35 - Sayı: 3, 209–211. https://ajindex.com/articles/620023

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