Journals / Türk Anestezi ve Reanimasyon Dergisi / 2011 / Cilt: 39 - Sayı: 6

The use of sugammadex in a patient with myasthenia gravis

Miyastenia gravisli bir olguda sugammadeks kullanımı

Pages
341–345
Publication Date
2022-11-04
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

This article reports the use of 4 mg kg-1 Sugammadex to reverse neuromuscular blockade in a myasthenia gravis case, where 0.6 mg kg-1 rocuronium was used as a neuromuscular blocking agent.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Myasthenia gravis is an autoimmune disease characterized by antibody formation against postsynaptic acetylcholine receptors.
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Key Findings & Data:Patients demonstrate increased sensitivity to nondepolarizing muscle relaxants.
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Conclusion & Impact:This article reports the use of 4 mg kg-1 Sugammadex to reverse neuromuscular blockade in a myasthenia gravis case, where 0.6 mg kg-1 rocuronium was used as a neuromuscular blocking agent.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Myasthenia gravis is an autoimmune disease characterized by antibody formation against postsynaptic acetylcholine receptors. Patients demonstrate increased sensitivity to nondepolarizing muscle relaxants. Sugammadex is a new selective nondepolarizing muscle relaxant-binding agent designed to reverse the effect of steroidal muscle relaxants like rocuronium and vecuronium. This article reports the use of 4 mg kg-1 Sugammadex to reverse neuromuscular blockade in a myasthenia gravis case, where 0.6 mg kg-1 rocuronium was used as a neuromuscular blocking agent.

Özet

Miyastenia gravis, postsinaptik asetilkolin reseptörlerine karşı antikor gelişimiyle karakterize otoimmün bir hastalıktır. Hastalarda nondepolarizan kas gevşeticilere karşı duyarlılık artmıştır. Sugammadeks, roküronyum ve veküronyum gibi steroid yapılı nondepolarizan kas gevşeticileri seçici şekilde bağlayarak, etkilerini kaldırmak üzere tasarlanmış yeni bir ilaçtır. Bu makalede kas gevşetici olarak 0.6 mg kg-1 roküronyum kullanılan miyastenia gravisli bir olguda, kas gücünün geri dönüşünü sağlamada 4 mg kg-1 sugammadeks kullanımı sunulmuştur.

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Cite This Article

KAZDAL, H., TOMAK, Y., BOSTAN, H. (2022). The use of sugammadex in a patient with myasthenia gravis. Türk Anestezi ve Reanimasyon Dergisi, Cilt: 39 - Sayı: 6, 341–345. https://ajindex.com/articles/619851

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References (3)

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