Journals / Türk Anestezi ve Reanimasyon Dergisi / 2007 / Cilt: 35 - Sayı: 3

Esmolol,remifentanly and esmolol+remifentanyl combinations effects on hemodynamic changes caused by laryngoscopy and tracheal intubation

Laringoskopi ve trakeal entübasyona bağlı hemodinamik değişiklikler üzerine esmolol,remifentanil ve esmolol+remifentanil kombinasyonunun etkileri

Pages
163–168
Publication Date
2022-11-05
DOI
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⚡ TL;DR(Too Long; Didn't Read)

In the remifentanil group measurements showed a signific ant increase in HR at the 1 minute after intubation when compared to baseline and preinduction, measurements RPP was higher at the 1 minute after intubati on in all groups when compared with preintubation Va lues, whif the SAP, DAP, and MAP values significantly increased only in esmolol and remifentanil, groups (p

📌 3 Key Takeaways

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Objective & Hypothesis:Aim: The efficacy of esmolol. umıfentanıl and esmo lol+remifentanil on changes in heart rate (HR) and arterial blood pressure (ABP) after laryngoscopy and tracheal intubation were compared.
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Key Findings & Data:Materials and Methods: Sixty patients (ASAI-II) were included in this study Before induction HR systolie and diastolic arterial pressure (SAP and DAP), mean arterial pressure (MAP) and Rate-Pressure, Product (RPP HRxSAP) values were measured three times with 1 minute intervals and the mean value of these mcasu rements was accepted as baseline.
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Conclusion & Impact:In the remifentanil group measurements showed a signific ant increase in HR at the 1 minute after intubation when compared to baseline and preinduction, measurements RPP was higher at the 1 minute after intubati on in all groups when compared with preintubation Va lues, whif the SAP, DAP, and MAP values significantly increased only in esmolol and remifentanil, groups (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Aim: The efficacy of esmolol. umıfentanıl and esmo lol+remifentanil on changes in heart rate (HR) and arterial blood pressure (ABP) after laryngoscopy and tracheal intubation were compared. Materials and Methods: Sixty patients (ASAI-II) were included in this study Before induction HR systolie and diastolic arterial pressure (SAP and DAP), mean arterial pressure (MAP) and Rate-Pressure, Product (RPP HRxSAP) values were measured three times with 1 minute intervals and the mean value of these mcasu rements was accepted as baseline. Patients were divided into three groups, Group ESM (esmolol group)reccived 2mg kg-1 esmolol IV Group REM (remifentanil group)1 ug kg-1 remifentanil IV while Group ESM+REM(esmolol +remifentanil group)reccived the mombination of 1mg kg-1 esmolol +0.5 ug kg-1 remifentanil IV.Before induction and intubation and through the 1. to 10. minute after intubation HR, SAP, DAP,MAP was recorded with 1 minute intervals and RPP was calculated according to this data.Results: There was no difference between the groups when demographic data HR, SAP, DAP, MAP and RPP values were compared but in all groups the HR values were significantly higher at the I. minute after intubation in comparison with preintubation values. In the remifentanil group measurements showed a signific ant increase in HR at the 1 minute after intubation when compared to baseline and preinduction, measurements RPP was higher at the 1 minute after intubati on in all groups when compared with preintubation Va lues, whif the SAP, DAP, and MAP values significantly increased only in esmolol and remifentanil, groups (p

Özet

Laringoskopı ve trakeal entübasyon sonucu kalp atmanızı (KAH) ve artçı kan basıncında meydana gelebilecek değişikliklerde esmolol,remifentanil ve esmolol+ remifentanilin etkilerini, karşılaştırmayı amaçladık. Gereç ye Yöntem: Çalışmaya 60 hasta (ASA I-II) dahil edildi. İndüksiyon öncesi 1'er dk arayla 3 kez bakılan KAH, sistolik arter basıncı (SAB), diyastolik arter basıncı (DAB) ortalama arter basıncı (OAB) ve hız basınç ürünü (HBÜ KAH x SAB) ölçümlerinin ortalaması bazal değer olarak alındı Grup ESM'e (esmolol grubu) 2 mg kg esmolol, Grup REM'e (remifentanil grubu) 1 ug kg remifentanil, Grup ESM+REM'e (esmolol+ remifentanil grubu) 1 mg kg ] esmolol + 0 5 ue kg ] remifentanil kombinasyonu intravenöz uygulandı İndüksiyon ve entübasyon öncesi ile entübasyon sonrası 10 dakikaya kadar olan KAH, SAB, DAB, OAB değerleri 1'er dk aralıkla ölçülerek bunlara bağlı HBÜ değerleri hesaplandı.Bulgular:Demografik veriler, KAH, SAB, DAB, OAB yo HBÜ açısından gruplar arasında anlamlı bir fark saptanmazken, grup içi değerlendirmede üç grupta da entübasyon öncesi KAH ile entübasyon sonrası 1. dk arasında anlamlı artış mevcuttu Remifentanil grubunda, bazal ve indüksiyon öncesi KAH değerlerine göre entübasyon sonrası 1 dk 'da artış görüldü Entübas yon oncesine göre entübasyon sonrası 1 dk 'da HBÜ değeri üç grupta da yüksek bulunurken, SAB, DAB ve OAB değerleri açısından yalnızca esmolol ve remifentanil grubundaki artış anlamlıydı (p

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Cite This Article

KARAMAN, S., FIRAT, V., ALTUNIŞIK, U., GÜNÜŞEN, İ. (2022). Esmolol,remifentanly and esmolol+remifentanyl combinations effects on hemodynamic changes caused by laryngoscopy and tracheal intubation. Türk Anestezi ve Reanimasyon Dergisi, Cilt: 35 - Sayı: 3, 163–168. https://ajindex.com/articles/618972

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