Journals / Turkish Journal of Pharmaceutical Sciences / 2016 / Cilt: 13 - Sayı: 3

Antioxidant and Anticholinesterase Activities of Essential Oil of Alseodaphne peduncularis Meisn

Alseodaphne peduncularis Meisn. Uçucu Yağının Antioksidan ve Antikolinesteraz Aktivitesi

Pages
347–350
Publication Date
2022-11-05
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The essential oil showed weak activity in the DPPH radical scavenging(IC50 of 253.2 µg/mL) and phenolic content (32.5 mg GA/g), while moderate inhibition activity against AChE (I: 45.2%) and BChE (I: 48.6%).

📌 3 Key Takeaways

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Objective & Hypothesis:This study was designed to investigate the antioxidant and anticholinesterase activities of the essential oils from Alseodaphne peduncularisMeisn.
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Key Findings & Data:GC and GC/MS analysis of the leaves oil showed thirty one components representing 72.6% of the oil.
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Conclusion & Impact:The essential oil showed weak activity in the DPPH radical scavenging(IC50 of 253.2 µg/mL) and phenolic content (32.5 mg GA/g), while moderate inhibition activity against AChE (I: 45.2%) and BChE (I: 48.6%).
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

This study was designed to investigate the antioxidant and anticholinesterase activities of the essential oils from Alseodaphne peduncularisMeisn. GC and GC/MS analysis of the leaves oil showed thirty one components representing 72.6% of the oil. The most abundant componentswere β-caryophyllene (24.0%), δ-cadinene (15.9%) and germacrene B (12.2%). The antioxidant activity was determined by DPPH (1,1-diphenyl2-picrylhydrazyl) radical scavenging and total phenolic content assays, while anticholinesterase activity assessed by measuring inhibition ofacetylcholinesterase (AChE) and butyrylcholinesterase (BChE) enzymes. The essential oil showed weak activity in the DPPH radical scavenging(IC50 of 253.2 µg/mL) and phenolic content (32.5 mg GA/g), while moderate inhibition activity against AChE (I: 45.2%) and BChE (I: 48.6%).

Özet

Bu çalışma Alseodaphne peduncularis Meisn. uçucu yağının antioksidan ve antikolinesteraz aktivitelerini araştırmak için tasarlanmıştır. GC ve GC/MS analizleri yaprak yağında %72,6 oranında otuz bir bileşen bulunduğunu göstermiştir. En çok bulunan bileşenler β-karyofilen (%24,0), δ-kadinen (15,9) ve germakren B (%12,2) dir. Antioksidan aktivite DPPH (1,1- difenil-2-pikrilhidrazil) radikal süpürme ve toplam fenolik içerik yöntemleriyle değerlendirilirken, antikolinesteraz aktivite asetilkolinesteraz (AChE) ve bütirilkolinesteraz (BChE) enzim inhibisyonu ölçülerek değerlendirilmiştir. Uçucu yağ, zayıf DPPH radikal süpürme aktivitesi (IC50 değeri 253,2 mg/mL) ve fenolik içerik (32,5 mg GA/g) gösterirken, AChE (I: %45,2) ve BChE (I: %48,6) inhibisyon aktivitesi orta düzeydedir.

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Cite This Article

SALLEH, W. M. N. H. W., AHMAD, F. (2022). Antioxidant and Anticholinesterase Activities of Essential Oil of Alseodaphne peduncularis Meisn. Turkish Journal of Pharmaceutical Sciences, Cilt: 13 - Sayı: 3, 347–350. https://ajindex.com/articles/613879

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References (1)

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