Journals / Turkish Journal of Obstetrics and Gynecology / 2018 / Cilt: 15 - Sayı: 2

Incidence of suspicious axillary lymph node involvement in fluorine-18 fluoro-D-glucose positron emission tomography/ computed tomography in gynecologic cancers

Jinekolojik kanserlerde flor-18 floro-D-glukoz pozitron emisyon tomografisi-bilgisayarlı tomografide şüpheli aksiller lenf nodu tutulumunun insidansı

Pages
99–104
Publication Date
2022-11-05
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Therewere three (7.5%) metachronous cancers out of 40 gynecologic cancers; two patients were explained above, the third patient with endometriumcancer, who was not histopathologically evaluated although the axillary SUVmax was

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: There is scarce information about axillary lymph node involvement in gynecologic cancers.
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Key Findings & Data:We analyzed the incidence of suspicious axillarylymph nodes in gynecologic cancers.Materials and Methods: We retrospectively analyzed the positron emission tomography/computed tomography findings of 251 patients with endometrial,cervical, and ovarian cancer.
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Conclusion & Impact:Therewere three (7.5%) metachronous cancers out of 40 gynecologic cancers; two patients were explained above, the third patient with endometriumcancer, who was not histopathologically evaluated although the axillary SUVmax was
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: There is scarce information about axillary lymph node involvement in gynecologic cancers. We analyzed the incidence of suspicious axillarylymph nodes in gynecologic cancers.Materials and Methods: We retrospectively analyzed the positron emission tomography/computed tomography findings of 251 patients with endometrial,cervical, and ovarian cancer. There is no cut-off value documented for axillary metastases from gynecologic cancers; therefore we adopted the cut-offstandardized uptake values (SUVs) proclaimed in breast cancer.Results: A total of 251 patients records were available for analysis; 40 patients (15.9%) with suspicious axillary lymph nodes were includedin the study. Twenty-one and a half percent (n=20/93) of patients with endometrium cancer, 14.1% (n=14/99) of patients with ovarian cancer, and10% (n=6/59) of those with cervical cancer had suspicious axillary lymph nodes. Patients with an maximum SUV (SUVmax) uptake higher than3 underwent axillary lymph node biopsy. None of them was found to have axillary metastases of gynecologic cancers in the pathologic evaluation.In one patient with endometrial cancer, an obscure breast ductal carcinoma was diagnosed, another patient with endometrial cancer was foundto have follicular lymphoma. The third patient with endometrial cancer had no malignancy in axillary lymph node biopsy, but had Hurthle cellneoplasia in a thyroid biopsy; the patient did not accept any surgical or medical treatment for endometrial cancer and died 23 months later. Therewere three (7.5%) metachronous cancers out of 40 gynecologic cancers; two patients were explained above, the third patient with endometriumcancer, who was not histopathologically evaluated although the axillary SUVmax was

Özet

Amaç: Jinekolojik kanserlerde aksiller lenf nodu tutulumunun prognostik önemi ve tedavisi açısından kısıtlı bilgiler mevcuttur. Bu çalışmanın amacı, jinekolojik kanserlerde şüpheli aksiller lenf nodu insidansını değerlendirmektir. Gereç ve Yöntem: Kliniğimize başvuran toplam 251 endometrium, serviks veya over kanseri tanısı konulmuş hastaların pozitron emisyon tomografisibilgisayarlı tomografi bulgularını retrospektif olarak analiz ettik. Jinekolojik kanserler için aksiller metastazı açıdan belgelenen herhangi bir sınır değer belirlenmemiş olması nedeniyle çalışmamızda meme kanseri için belirlenen standart uptake değerini (SUV) sınır değer olarak kabul ettik. Bulgular: Analizler için toplam 251 hasta kaydı mevcuttu. Şüpheli aksiller lenf nodu olan 40 hasta (%15,9) çalışmaya dahil edildi. Endometrium kanseri olan hastaların %21,5’inde (n=20/93), over kanseri olan hastaların %14,1’inde (n=14/99) ve serviks kanseri olan hastaların %10’unda (n=6/59) şüpheli aksiller lenf nodu tespit edildi. Maksimum SUV (SUVmaks) değeri 3’ten yüksek bulunan 5 hastada aksiller lenf nodundan biyopsi alındı. Patolojik değerlendirmede hiçbir hastada primer jinekolojik kansere ait aksiller metastaz saptanmadı. Endometrium kanseri olan bir hastada invaziv meme karsinomu, endometrium kanseri olan başka bir hastada foliküler lenfoma tanısı konuldu. Endometrium kanseri olan üçüncü hastada aksiller lenf nodu biyopsisinde tümör tespit edilmedi ancak tiroid biyopsisinde Hurthle hücre neoplazisi saptandı, bu hasta endometrium kanseri için herhangi bir cerrahi veya medikal tedaviyi kabul etmedi ve 23 ay sonra hayatını kaybetmiştir. Çalışmamıza şüpheli aksiller lenf nodu ile dahil olan 40 hastanın 3’ünde (%7,5) metakron kanser izlendi; iki hasta yukarıdaki paragrafta açıklandı, üçüncü ve endometrium kanser tanısı olan hastada rektosigmoid kanseri ve glioblastoma metakron olarak izlendi, bu hastaya SUVmaks

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Cite This Article

ERDEMOĞLU, E., ÖZKAN, E. E., İŞCAN, S. C., ÇERÇİ, S. S., ERDEMOĞLU, E., RAOUFİ, J., HANEDAN, C. (2022). Incidence of suspicious axillary lymph node involvement in fluorine-18 fluoro-D-glucose positron emission tomography/ computed tomography in gynecologic cancers. Turkish Journal of Obstetrics and Gynecology, Cilt: 15 - Sayı: 2, 99–104. https://ajindex.com/articles/613032

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