Journals / Turkish Journal of Medical Sciences / 2019 / Cilt: 49 - Sayı: 5

Quantitative analysis of the optic nerve head parameters in patients with age-related macular degeneration

Pages
1518–1523
Publication Date
2022-11-04
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

Because AMDmanifests with progressive ocular damage, including the optic nerve head, examination of the cup shape may be important during thefollow-up of these patients.

📌 3 Key Takeaways

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Objective & Hypothesis:Background/aim: To evaluate the topographic parameters of the optic disc of patients with age-related macular degeneration (AMD)by performing confocal scanning laser ophthalmoscopy.Materials and methods: This prospective study included 41 eyes of 41 patients with neovascular AMD, 56 eyes of 56 patients withnonneovascular AMD, and 48 eyes of 48 healthy control subjects.
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Key Findings & Data:Images of the optic nerve head of all of the participants were obtainedusing Heidelberg retinal tomography III software 3.1.
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Conclusion & Impact:Because AMDmanifests with progressive ocular damage, including the optic nerve head, examination of the cup shape may be important during thefollow-up of these patients.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Background/aim: To evaluate the topographic parameters of the optic disc of patients with age-related macular degeneration (AMD)by performing confocal scanning laser ophthalmoscopy.Materials and methods: This prospective study included 41 eyes of 41 patients with neovascular AMD, 56 eyes of 56 patients withnonneovascular AMD, and 48 eyes of 48 healthy control subjects. Images of the optic nerve head of all of the participants were obtainedusing Heidelberg retinal tomography III software 3.1. The following stereometric parameters were measured for each participant: discarea, cup area, rim area, cup volume, rim volume, cup-to-disc ratio, mean cup depth, maximum cup depth, cup shape, and mean retinalnerve fiber layer thickness.Results: The cup shape values of the patients with neovascular and nonneovascular AMD were significantly different from those of thecontrol subjects (P = 0.002 and P 0.05). No significant differences were observed among the 3 groups with respect to the other optic discparameters (P > 0.05).Conclusion: These data showed that the deterioration of the cup shape was an important finding in patients with AMD. Because AMDmanifests with progressive ocular damage, including the optic nerve head, examination of the cup shape may be important during thefollow-up of these patients.

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Cite This Article

ÇITIRIK, M., ŞİMŞEK, T., ÖZATEŞ, S., ŞİMŞEK, M. (2022). Quantitative analysis of the optic nerve head parameters in patients with age-related macular degeneration. Turkish Journal of Medical Sciences, Cilt: 49 - Sayı: 5, 1518–1523. https://ajindex.com/articles/610152

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References (13)

  1. Mitchell P, Liew G, Gopinath B, Wong TY. Age-related macular degeneration. Lancet 2018
  2. 392 (10153): 1147-1159. doi: 10.1016/S0140-6736(18)31550-2 2. Lambert NG, ElShelmani H, Singh MK, Mansergh FC, Wride MA et al. Risk factors and biomarkers of age-related macular degeneration. Progress in Retinal and Eye Research 2016
  3. doi: 10.1016/j.preteyeres.2016.04.003 3. Gusek GC, Jonas JB, Naumann GO. Retinal vascular occlusions are independent of optic disk size. A morphometric study of 140 patients. Klinische Monatsblätter für Augenheilkunde 1990
  4. 197 (1): 14-17. doi: 10.1055/s-2008-1046236 4. Faschinger C, Mossböck G. Myopia and glaucoma. Wiener Medizinische Wochenschrift 2007
  5. 157 (7-8): 173-177. doi: 10.1007/s10354-007-0380-3 5. Mamikonyan VR, Galoyan NS, Sheremet NL, Kazaryan EE, Shmeleva-Demir OA et al. Tomography findings in optic nerve head and retina in differential diagnosis between normal-tension glaucoma and ischemic optic neuropathies. Vestnik Oftalmologii 2015
  6. 131 (4): 15-20. doi: 10.17116/ oftalma2015131415-20 6. Trick GL, Calotti FY, Skarf B. Advances in imaging of the optic disk and retinal nerve fiber layer. Journal of NeuroOphthalmology 2006
  7. 26 (4): 284-295. doi: 10.1097/01. wno.0000249327.65227.67 7. Law SK, Sohn YH, Hoffman D, Small K, Coleman AL et al. Optic disk appearance in advanced age-related macular degeneration. American Journal of Ophthalmology 2004
  8. 138 (1): 38-45. doi: 10.1016/j.ajo.2004.02.021 8. Hall ER, Klein BE, Knudtson MD, Meuer SM, Klein R. Age-related macular degeneration and optic disk cupping: the Beaver Dam Eye Study. American Journal of Ophthalmology 2006
  9. 141 (3): 494-497. doi: 10.1016/j.ajo.2005.10.049 9. The Eye Disease Case-Control Study Group. Risk factors for neovascular age-related macular degeneration. Archives of Ophthalmology 1992
  10. 110 (12): 1701-1708. doi: 10.1001/archopht.1992.01080240041025 10. Bressler NM, Bressler SB, Fine SL. Age-related macular degeneration. Survey of Ophthalmology 1988
  11. 32 (6): 375-413. doi: 10.1016/0039-6257(88)90052-5 11. Cohen SY, Dubois L, Grenet T, Nghiem-Buffet S, Jung C et al. Peripapillary retinal pigment epithelium changes in agerelated macular degeneration. Retina 2016
  12. 36 (3): 458-464. doi: 10.1097/IAE.0000000000000741 12. Sigler EJ, Mascarenhas KG, Tsai JC, Loewen NA. Clinicopathologic correlation of disc and peripapillary region using SD-OCT. Optometry and Vision Science 2013
  13. 90 (1): 84-93. doi: 10.1097/ OPX.0b013e318278fc15 13. Yenice E, Şengün A, Soyugel