Journals / Retina-Vitreus / 2016 / Cilt: 24 - Sayı: 4

Current Epidemiology, Pathophysiology, and Risk Factors in Retinopathy of Prematurity

Prematüre Retinopatisinde Güncel Epidemiyoloji, Patofizyoloji ve Risk Faktörleri

Pages
263–270
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In this review, the current epidemiology, pathophysiology, and risk factors of ROP have been evaluated to better understand underlying mechanisms of ROP.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Retinopathy of prematurity (ROP) is one of the leading cause of preventable childhood blindness associated with abnormal retinal fibrovascular proliferation taking place only in premature infants.
📊
Key Findings & Data:Low gestational age and birth weight are the main known risk factors for ROP.
💡
Conclusion & Impact:In this review, the current epidemiology, pathophysiology, and risk factors of ROP have been evaluated to better understand underlying mechanisms of ROP.
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Retinopathy of prematurity (ROP) is one of the leading cause of preventable childhood blindness associated with abnormal retinal fibrovascular proliferation taking place only in premature infants. Low gestational age and birth weight are the main known risk factors for ROP. Nowadays, the numbers of sight-threatening complications associated with ROP have been reduced by understanding pathophysiology of ROP, new screening tools, and novel treatment options. In this review, the current epidemiology, pathophysiology, and risk factors of ROP have been evaluated to better understand underlying mechanisms of ROP.

Özet

Prematüre retinopatisi (PR) sadece prematüre infantlarda, çocukluk çağında retina dokusunda anormal fibrovasküler çoğalma ile ortaya çıkan önlenebilir körlüğün en önemli nedenlerinden biridir. Düşük doğum haftası ve doğum ağırlığı PR için bilinen en önemli risk faktörleridir. Günümüzde PR ile ilişkili görmeyi tehdit eden komplikasyonların sayısı; PR patofizyolojisi, yeni tarama araçları ve yeni tedavi seçenekleri sayesinde düşürülmüştür. Bu yazıda, PR gelişiminde altta yatan mekanizmanın daha iyi anlaşılabilmesi için güncel epidemiyoloji, patofizyoloji ve risk faktörleri ele alınmıştır.

🔖

Cite This Article

ÖZCAN, P. Y., ÇITIRIK, M., ÖZÇALIŞKAN, Ş. (2016). Current Epidemiology, Pathophysiology, and Risk Factors in Retinopathy of Prematurity. Retina-Vitreus, Cilt: 24 - Sayı: 4, 263–270. https://ajindex.com/articles/306840

References (11)

  1. Terry TL. Extreme prematurity and fibroblastic overgrowth of persistent vascular sheath behind each crystalline lens: (1) preliminary report. Am J Ophthalmol 1942;25:203-4.
  2. Niranjan HS, Benakappa N, Reddy KR, et al. Retinopathy of PrematurityPromising Newer Modalities of Treatment. Indian Pediatrics. 2012;49:139-43. Patz A. The role of oxygen in retrolental fibroplasia. Trans Am Ophthalmol Soc. 1968;66:940-985.
  3. Ashton N, Ward B, Serpell G. Effect of oxygen on developing retinal vessels with particular reference to the problem of retrolental fibroplasia. Br J Ophthalmol.1954;38:397-432.
  4. Gergely K, Gerinec A. Retinopathy of prematurity--epidemics, incidence, prevalence, blindness. Bratisl Lek Listy. 2010;111:514-7. Fleck B. Opthalmology. In: Rennie JM, ed. Rennie and Robertson's Textbook of Neonatology. 5th ed. London: Churchill Livingstone Elsevier; 2012:837-848.
  5. Askin DF, Diehl-Jones W. Retinopathy of prematurity. Crit Care Nurs Clin North Am. 2009;21:213-33. Quimson SK. Retinopathy of Prematurity: Pathogenesis and Current Treatment Options. Neonatal Netw. 2015;34:284-7. Fierson WM; American Academy of Pediatrics Section on Ophthalmology; American Academy of Ophthalmology; American Association for Pediatric Ophthalmology and Strabismus; American Association of Certified Orthoptists. Screening examination of premature infants for retinopathy of prematurity. Pediatrics 2013;131:189-95.
  6. Lawn JE, Gravett MG, Nunes TM, et al. GAPPS Review Group. Global report on preterm birth and stillbirth (1 of 7): definitions, description of the burden and opportunities to improve data. BMC Pregnancy Childbirth. 2010;10:S1 Liu L, Johnson HL, Cousens S, et al. for the Child Health Epidemiology Reference Group of WHO, UNICEF. Global, regional, and national causes of child mortality: an updated systematic analysis for 2010 with time trends since 2000. Lancet. 2012;379:2151-61.
  7. Hellström A, Smith LE, Dammann O. Retinopathy of prematurity. Lancet. 2013;382:1445-57.
  8. Bas AY, Koc E, Dilmen U; ROP Neonatal Study Group. Incidence and severity of retinopathy of prematurity in Turkey. Br J Oph- thalmol 2015;99:1311-4.
  9. Ozcan PY, Con R, Celik HT. [Incidence, risk factors and treatment outcomes of retinopathy of prematurity in the southeastern Anatolian region province of Şanlıurfa in Turkey]. Turkiye Klinikleri J Med Sci 2015;35:240-7.
  10. Öner A, Özkırış A, Güneş T. [Retinopathy of prematurity: screening resluts for 2 years]. Erciyes Tıp Dergisi 2005;27:104-9.
  11. Özcan E, Yenice Ö, Kazokoğlu H,