Journals / Türk Kardiyoloji Derneği Arşivi / 2014 / Cilt: 42 - Sayı: 8

Koroner aterosklerozu yükü ile asimetrik dimetilarjinin, karotis intima medya kalınlığı ve endotel fonksiyonu arasındaki ilişki

The association between coronary atherosclerotic burden and asymmetric dimethylarginine, carotis intima media thickness and endothelial function

Pages
701–709
Publication Date
2022-11-05
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

Results: GSS was higher in ACS than SCA (75.4 vs 54.9;p

📌 3 Key Takeaways

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Objective & Hypothesis:Objectives: Detection of extent and severity of atherosclero- sis using easy, non-invasive methods is of great importance.Atherosclerotic burden may be evaluated with the Gen- sini scoring system (GSS).
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Key Findings & Data:Study design: Consecutive patients who had undergonecoronary angiography were evaluated. 50 patients with acutecoronary syndrome (ACS), 50 patients with stable coronaryartery disease (SCA), and 50 patients with normal coronaryarteries (NCA) were included.
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Conclusion & Impact:Results: GSS was higher in ACS than SCA (75.4 vs 54.9;p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objectives: Detection of extent and severity of atherosclero- sis using easy, non-invasive methods is of great importance.Atherosclerotic burden may be evaluated with the Gen- sini scoring system (GSS). Carotis intima media thickness(CIMT), plasma asymmetric dimethyl arginine (ADMA) level,and endothelial dysfunction are well known surrogate markersof atherosclerosis. The aim of this study was to evaluate therelationship between atherosclerotic burden determined bythe GSS, and ADMA, CIMT and endothelial function. Study design: Consecutive patients who had undergonecoronary angiography were evaluated. 50 patients with acutecoronary syndrome (ACS), 50 patients with stable coronaryartery disease (SCA), and 50 patients with normal coronaryarteries (NCA) were included. All subjects GSS, ADMA, CIMTand endothelial functions were evaluated and compared. Results: GSS was higher in ACS than SCA (75.4 vs 54.9;p

Özet

Amaç: Aterosklerozun şiddetinin ve yaygınlığının basit veinvaziv olmayan yöntemlerle tespiti oldukça önemlidir. Ate- roskleroz yükü Gensini skor sistemi (GSS) kullanılarak be- lirlenebilmektedir. Karotis intima medya kalınlığı (KİMK),plazma asimetrik dimetilarjinin (ADMA) seviyesi ve endotelfonksiyon bozukluğu aterosklerozun iyi bilinen belirteçleridir.Bu çalışmanın amacı GSS ile tespit edilen ateroskleroz yüküile ADMA, KİMK ve endotel fonksiyon bozukluğu arasındakiilişkiyi incelemektir.Çalışma planı: Koroner anjiyografi yapılmış olan ardışık has- talar değerlendirildi. Akut koroner sendromlu (AKS) 50 hasta,stabil koroner arter (SKA) hastalığı olan 50 ve koroner arter- leri normal (NKA) 50 olgu çalışmaya alındı. Çalışmaya alınantüm olguların GSS, ADMA, KİMK ve endotel fonksiyonları öl- çüldü ve karşılaştırıldı. Bulgular: GSS değerleri AKS grubunda SKA grubuna göredaha yüksekti (75.4 ve 54.9; p

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Cite This Article

GÖRMÜŞ, U., ACAR, Z., ŞAHİN, S., ÇİFTÇİ, Ç., CİVAN, M., ZİYREK, M., ERDEM, Ş., CAN, F. (2022). Koroner aterosklerozu yükü ile asimetrik dimetilarjinin, karotis intima medya kalınlığı ve endotel fonksiyonu arasındaki ilişki. Türk Kardiyoloji Derneği Arşivi, Cilt: 42 - Sayı: 8, 701–709. https://ajindex.com/articles/603057

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