Propofol Versus Thiopental for Rapid-Sequence Induction in Isolated Systolic Hypertensive Patients: A Factorial Randomized Double-Blind Clinical Trial
Hızlı Seri Anestezi İndüksiyonu Uygulanan İzole Sistolik Hipertansiyonlu Hastalarda Propofol ve Tiopentalin Karşılaştırılması: Faktöriyel Randomize Çift Kör Klinik Araştırma
Objective: We investigated the effects of four different anaesthesiainduction protocols on the haemodynamic response to laryngoscopyand tracheal intubation during rapid-sequence induction(RSI) in systolic hypertensive patients.Methods: One hundred and twenty hypertensive adult patients(systolic pressure >140 mmHg and diastolic pressure 20% were considered to be significant.Results: Patients receiving remifentanil+propofol had a reductionin the systolic and mean blood pressure >20% when comparedto patients receiving remifentanil and thiopental: systolic valueswere 125±27 mmHg in the remifentanil+propofol group versus153±35 mmHg in the remifentanil+thiopental group 1 minuteafter intubation (p
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Objective & Hypothesis:Objective: We investigated the effects of four different anaesthesiainduction protocols on the haemodynamic response to laryngoscopyand tracheal intubation during rapid-sequence induction(RSI) in systolic hypertensive patients.Methods: One hundred and twenty hypertensive adult patients(systolic pressure >140 mmHg and diastolic pressure 20% were considered to be significant.Results: Patients receiving remifentanil+propofol had a reductionin the systolic and mean blood pressure >20% when comparedto patients receiving remifentanil and thiopental: systolic valueswere 125±27 mmHg in the remifentanil+propofol group versus153±35 mmHg in the remifentanil+thiopental group 1 minuteafter intubation (p
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Key Findings & Data:Objective: We investigated the effects of four different anaesthesiainduction protocols on the haemodynamic response to laryngoscopyand tracheal intubation during rapid-sequence induction(RSI) in systolic hypertensive patients.Methods: One hundred and twenty hypertensive adult patients(systolic pressure >140 mmHg and diastolic pressure 20% were considered to be significant.Results: Patients receiving remifentanil+propofol had a reductionin the systolic and mean blood pressure >20% when comparedto patients receiving remifentanil and thiopental: systolic valueswere 125±27 mmHg in the remifentanil+propofol group versus153±35 mmHg in the remifentanil+thiopental group 1 minuteafter intubation (p
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Conclusion & Impact:Objective: We investigated the effects of four different anaesthesiainduction protocols on the haemodynamic response to laryngoscopyand tracheal intubation during rapid-sequence induction(RSI) in systolic hypertensive patients.Methods: One hundred and twenty hypertensive adult patients(systolic pressure >140 mmHg and diastolic pressure 20% were considered to be significant.Results: Patients receiving remifentanil+propofol had a reductionin the systolic and mean blood pressure >20% when comparedto patients receiving remifentanil and thiopental: systolic valueswere 125±27 mmHg in the remifentanil+propofol group versus153±35 mmHg in the remifentanil+thiopental group 1 minuteafter intubation (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters
Abstract
Objective: We investigated the effects of four different anaesthesiainduction protocols on the haemodynamic response to laryngoscopyand tracheal intubation during rapid-sequence induction(RSI) in systolic hypertensive patients.Methods: One hundred and twenty hypertensive adult patients(systolic pressure >140 mmHg and diastolic pressure 20% were considered to be significant.Results: Patients receiving remifentanil+propofol had a reductionin the systolic and mean blood pressure >20% when comparedto patients receiving remifentanil and thiopental: systolic valueswere 125±27 mmHg in the remifentanil+propofol group versus153±35 mmHg in the remifentanil+thiopental group 1 minuteafter intubation (p
Özet
Amaç: Bu çalışmada izole sistolik hipertansiyonu olan hastalarda hızlı - seri anestezi indüksiyonu sırasında dört farklı protokolde ilaç uygulamasının, laringoskopi ve entübasyonda hemodinamik cevap üzerine olan etkileri karşılaştırıldı. Yöntemler: Çalışmaya, izole sistolik hipertansiyonu olan (sistolik kan basıncı >140 mmHg, diastolik kan basıncı
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Cite This Article
YILMAZ, A. A., VURAL, Ç., ALANOĞLU, Z., ASLAN, N. A. (2022). Propofol Versus Thiopental for Rapid-Sequence Induction in Isolated Systolic Hypertensive Patients: A Factorial Randomized Double-Blind Clinical Trial. Turkish Journal of Anaesthesiology and Reanimation, Cilt: 46 - Sayı: 5, 367–372. https://ajindex.com/articles/600035
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